163 related articles for article (PubMed ID: 21850236)
1. Regulation of cathepsin G reduces the activation of proinsulin-reactive T cells from type 1 diabetes patients.
Zou F; Schäfer N; Palesch D; Brücken R; Beck A; Sienczyk M; Kalbacher H; Sun Z; Boehm BO; Burster T
PLoS One; 2011; 6(8):e22815. PubMed ID: 21850236
[TBL] [Abstract][Full Text] [Related]
2. Invariant chain processing is independent of cathepsin variation between primary human B cells/dendritic cells and B-lymphoblastoid cells.
Reich M; Zou F; Sieńczyk M; Oleksyszyn J; Boehm BO; Burster T
Cell Immunol; 2011; 269(2):96-103. PubMed ID: 21543057
[TBL] [Abstract][Full Text] [Related]
3. Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells.
Reich M; Lesner A; Legowska A; Sieńczyk M; Oleksyszyn J; Boehm BO; Burster T
Mol Immunol; 2009 Sep; 46(15):2994-9. PubMed ID: 19615749
[TBL] [Abstract][Full Text] [Related]
4. Processing and presentation of (pro)-insulin in the MHC class II pathway: the generation of antigen-based immunomodulators in the context of type 1 diabetes mellitus.
Burster T; Boehm BO
Diabetes Metab Res Rev; 2010 May; 26(4):227-38. PubMed ID: 20503254
[TBL] [Abstract][Full Text] [Related]
5. Downregulation of cathepsin G reduces the activation of CD4+ T cells in murine autoimmune diabetes.
Zou F; Lai X; Li J; Lei S; Hu L
Am J Transl Res; 2017; 9(11):5127-5137. PubMed ID: 29218110
[TBL] [Abstract][Full Text] [Related]
6. Cathepsin G: roles in antigen presentation and beyond.
Burster T; Macmillan H; Hou T; Boehm BO; Mellins ED
Mol Immunol; 2010 Jan; 47(4):658-65. PubMed ID: 19910052
[TBL] [Abstract][Full Text] [Related]
7. A proinsulin 74-90-derived protease-resistant, altered peptide ligand increases TGF-beta 1 secretion in PBMC from patients with type 1 diabetes mellitus.
van Aalst D; Kalbacher H; Palesch D; Zou F; Spyrantis A; Rosinger S; Boehm BO; Burster T
J Leukoc Biol; 2010 May; 87(5):943-8. PubMed ID: 20110445
[TBL] [Abstract][Full Text] [Related]
8. Recognition of Ii-Key/MHC class II epitope hybrids derived from proinsulin and GAD peptides by T cells in type 1 diabetes.
Vadacca M; Valorani MG; von Hofe E; Kallinteris NL; Buzzetti R; Pozzilli P
Horm Metab Res; 2011 Jun; 43(7):483-8. PubMed ID: 21512962
[TBL] [Abstract][Full Text] [Related]
9. A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Matsumoto Y; Kishida K; Matsumoto M; Matsuoka S; Kohyama M; Suenaga T; Arase H
Biochem Biophys Res Commun; 2021 Jan; 534():680-686. PubMed ID: 33208230
[TBL] [Abstract][Full Text] [Related]
10. Proinsulin C-peptide is an autoantigen in people with type 1 diabetes.
So M; Elso CM; Tresoldi E; Pakusch M; Pathiraja V; Wentworth JM; Harrison LC; Krishnamurthy B; Thomas HE; Rodda C; Cameron FJ; McMahon J; Kay TWH; Mannering SI
Proc Natl Acad Sci U S A; 2018 Oct; 115(42):10732-10737. PubMed ID: 30275329
[TBL] [Abstract][Full Text] [Related]
11. Application of a novel highly sensitive activity-based probe for detection of cathepsin G.
Zou F; Schmon M; Sienczyk M; Grzywa R; Palesch D; Boehm BO; Sun ZL; Watts C; Schirmbeck R; Burster T
Anal Biochem; 2012 Feb; 421(2):667-72. PubMed ID: 22178917
[TBL] [Abstract][Full Text] [Related]
12. Cathepsin G is differentially expressed in primary human antigen-presenting cells.
Stoeckle C; Sommandas V; Adamopoulou E; Belisle K; Schiekofer S; Melms A; Weber E; Driessen C; Boehm BO; Tolosa E; Burster T
Cell Immunol; 2009; 255(1-2):41-5. PubMed ID: 19036358
[TBL] [Abstract][Full Text] [Related]
13. Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.
Roep BO; Solvason N; Gottlieb PA; Abreu JRF; Harrison LC; Eisenbarth GS; Yu L; Leviten M; Hagopian WA; Buse JB; von Herrath M; Quan J; King RS; Robinson WH; Utz PJ; Garren H; ; Steinman L
Sci Transl Med; 2013 Jun; 5(191):191ra82. PubMed ID: 23803704
[TBL] [Abstract][Full Text] [Related]
14. Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin.
Griffin AC; Zhao W; Wegmann KW; Hickley WF
Am J Pathol; 1995 Sep; 147(3):845-57. PubMed ID: 7545875
[TBL] [Abstract][Full Text] [Related]
15. Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.
Hoelen H; Zaldumbide A; van Leeuwen WF; Torfs EC; Engelse MA; Hassan C; Lebbink RJ; de Koning EJ; Resssing ME; de Ru AH; van Veelen PA; Hoeben RC; Roep BO; Wiertz EJ
PLoS One; 2015; 10(6):e0128206. PubMed ID: 26107514
[TBL] [Abstract][Full Text] [Related]
16. GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.
Oling V; Marttila J; Ilonen J; Kwok WW; Nepom G; Knip M; Simell O; Reijonen H
J Autoimmun; 2005 Nov; 25(3):235-43. PubMed ID: 16263242
[TBL] [Abstract][Full Text] [Related]
17. T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin.
Congia M; Patel S; Cope AP; De Virgiliis S; Sønderstrup G
Proc Natl Acad Sci U S A; 1998 Mar; 95(7):3833-8. PubMed ID: 9520453
[TBL] [Abstract][Full Text] [Related]
18. Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes.
Toma A; Laïka T; Haddouk S; Luce S; Briand JP; Camoin L; Connan F; Lambert M; Caillat-Zucman S; Carel JC; Muller S; Choppin J; Lemonnier F; Boitard C
Diabetes; 2009 Feb; 58(2):394-402. PubMed ID: 19011169
[TBL] [Abstract][Full Text] [Related]
19. Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain.
Mizuochi T; Yee ST; Kasai M; Kakiuchi T; Muno D; Kominami E
Immunol Lett; 1994 Dec; 43(3):189-93. PubMed ID: 7721331
[TBL] [Abstract][Full Text] [Related]
20. Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.
Blahnik G; Uchtenhagen H; Chow IT; Speake C; Greenbaum C; Kwok WW; James EA
Cell Immunol; 2019 Jan; 335():68-75. PubMed ID: 30428974
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
