BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 21850438)

  • 1. Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay.
    Tallarida C; Song K; Raffa RB; Rawls SM
    Amino Acids; 2012 Jun; 42(6):2521-4. PubMed ID: 21850438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glutamate carboxypeptidase II (GCPII) inhibitor 2-PMPA reduces rewarding effects of the synthetic cathinone MDPV in rats: a role for N-acetylaspartylglutamate (NAAG).
    Hicks C; Gregg RA; Nayak SU; Cannella LA; Schena GJ; Tallarida CS; Reitz AB; Smith GR; Rawls SM
    Psychopharmacology (Berl); 2017 Jun; 234(11):1671-1681. PubMed ID: 28251297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
    Ha D; Bing SJ; Ahn G; Kim J; Cho J; Kim A; Herath KH; Yu HS; Jo SA; Cho IH; Jee Y
    FEBS J; 2016 Sep; 283(18):3438-56. PubMed ID: 27444540
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester Prodrugs.
    Nedelcovych M; Dash RP; Tenora L; Zimmermann SC; Gadiano AJ; Garrett C; Alt J; Hollinger KR; Pommier E; Jančařík A; Rojas C; Thomas AG; Wu Y; Wozniak K; Majer P; Slusher BS; Rais R
    Mol Pharm; 2017 Oct; 14(10):3248-3257. PubMed ID: 28763226
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neuroprotection produced by the NAALADase inhibitor 2-PMPA in rat cerebellar neurons.
    Tortella FC; Lin Y; Ved H; Slusher BS; Dave JR
    Eur J Pharmacol; 2000 Aug; 402(1-2):31-7. PubMed ID: 10940354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Local enema treatment to inhibit FOLH1/GCPII as a novel therapy for inflammatory bowel disease.
    Date AA; Rais R; Babu T; Ortiz J; Kanvinde P; Thomas AG; Zimmermann SC; Gadiano AJ; Halpert G; Slusher BS; Ensign LM
    J Control Release; 2017 Oct; 263():132-138. PubMed ID: 28159515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Binding of the glutamate carboxypeptidase II (NAALADase) inhibitor 2-PMPA to rat brain membranes.
    Tiffany CW; Cai NS; Rojas C; Slusher BS
    Eur J Pharmacol; 2001 Sep; 427(2):91-6. PubMed ID: 11557259
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Riluzole attenuates the effects of chemoconvulsants acting on glutamatergic and GABAergic neurotransmission in the planarian Dugesia tigrina.
    Ramakrishnan L; Dalhoff Z; Fettig SL; Eggerichs MR; Nelson BE; Shrestha B; Elshikh AH; Karki P
    Eur J Pharmacol; 2013 Oct; 718(1-3):493-501. PubMed ID: 23872399
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice.
    Luszczki JJ; Mohamed M; Czuczwar SJ
    Eur J Pharmacol; 2006 Feb; 531(1-3):66-73. PubMed ID: 16403497
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Still NAAG'ing After All These Years: The Continuing Pursuit of GCPII Inhibitors.
    Vornov JJ; Hollinger KR; Jackson PF; Wozniak KM; Farah MH; Majer P; Rais R; Slusher BS
    Adv Pharmacol; 2016; 76():215-55. PubMed ID: 27288079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA).
    Rais R; Rojas C; Wozniak K; Wu Y; Zhao M; Tsukamoto T; Rudek MA; Slusher BS
    J Pharm Biomed Anal; 2014 Jan; 88():162-9. PubMed ID: 24055700
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NAALADase inhibition protects motor neurons against chronic glutamate toxicity.
    Thomas AG; Corse AM; Coccia CF; Bilak MM; Rothstein JD; Slusher BS
    Eur J Pharmacol; 2003 Jun; 471(3):177-84. PubMed ID: 12826236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of glutamate carboxypeptidase II (NAALADase) protects against dynorphin A-induced ischemic spinal cord injury in rats.
    Long JB; Yourick DL; Slusher BS; Robinson MB; Meyerhoff JL
    Eur J Pharmacol; 2005 Jan; 508(1-3):115-22. PubMed ID: 15680261
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA.
    Nonaka T; Yamada T; Ishimura T; Zuo D; Moffett JR; Neale JH; Yamamoto T
    Mol Pain; 2017 Jan; 13():1744806917697008. PubMed ID: 28326936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors.
    Rong SB; Zhang J; Neale JH; Wroblewski JT; Wang S; Kozikowski AP
    J Med Chem; 2002 Sep; 45(19):4140-52. PubMed ID: 12213057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. S1 pocket of glutamate carboxypeptidase II: a new binding site for amyloid-β degradation.
    Lee SK; Kim H; Cheong YH; Kim MJ; Jo SA; Youn HS; Park SI
    Biochem Biophys Res Commun; 2013 Sep; 438(4):765-71. PubMed ID: 23891752
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human glutamate carboxypeptidase II inhibition: structures of GCPII in complex with two potent inhibitors, quisqualate and 2-PMPA.
    Mesters JR; Henning K; Hilgenfeld R
    Acta Crystallogr D Biol Crystallogr; 2007 Apr; 63(Pt 4):508-13. PubMed ID: 17372356
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glutamate carboxypeptidase II: an amyloid peptide-degrading enzyme with physiological function in the brain.
    Kim MJ; Chae SS; Koh YH; Lee SK; Jo SA
    FASEB J; 2010 Nov; 24(11):4491-502. PubMed ID: 20624932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NAALADase (GCP II) inhibition prevents cocaine-kindled seizures.
    Witkin JM; Gasior M; Schad C; Zapata A; Shippenberg T; Hartman T; Slusher BS
    Neuropharmacology; 2002 Sep; 43(3):348-56. PubMed ID: 12243764
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of glutamate carboxypeptidase II hydrolysis of N-acetylaspartylglutamate (NAAG) in crayfish nervous tissue is mediated by glial glutamate and acetylcholine receptors.
    Urazaev AK; Grossfeld RM; Lieberman EM
    J Neurochem; 2005 May; 93(3):605-10. PubMed ID: 15836619
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.