BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 21853155)

  • 1. Let-7a is a direct EWS-FLI-1 target implicated in Ewing's sarcoma development.
    De Vito C; Riggi N; Suvà ML; Janiszewska M; Horlbeck J; Baumer K; Provero P; Stamenkovic I
    PLoS One; 2011; 6(8):e23592. PubMed ID: 21853155
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.
    Tirado OM; Mateo-Lozano S; Villar J; Dettin LE; Llort A; Gallego S; Ban J; Kovar H; Notario V
    Cancer Res; 2006 Oct; 66(20):9937-47. PubMed ID: 17047056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells.
    Riggi N; Suvà ML; De Vito C; Provero P; Stehle JC; Baumer K; Cironi L; Janiszewska M; Petricevic T; Suvà D; Tercier S; Joseph JM; Guillou L; Stamenkovic I
    Genes Dev; 2010 May; 24(9):916-32. PubMed ID: 20382729
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.
    Leacock SW; Basse AN; Chandler GL; Kirk AM; Rakheja D; Amatruda JF
    Dis Model Mech; 2012 Jan; 5(1):95-106. PubMed ID: 21979944
    [TBL] [Abstract][Full Text] [Related]  

  • 5. EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.
    Riggi N; Suvà ML; Suvà D; Cironi L; Provero P; Tercier S; Joseph JM; Stehle JC; Baumer K; Kindler V; Stamenkovic I
    Cancer Res; 2008 Apr; 68(7):2176-85. PubMed ID: 18381423
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A molecular function map of Ewing's sarcoma.
    Kauer M; Ban J; Kofler R; Walker B; Davis S; Meltzer P; Kovar H
    PLoS One; 2009; 4(4):e5415. PubMed ID: 19404404
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.
    Kinsey M; Smith R; Iyer AK; McCabe ER; Lessnick SL
    Cancer Res; 2009 Dec; 69(23):9047-55. PubMed ID: 19920188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IGF1 is a common target gene of Ewing's sarcoma fusion proteins in mesenchymal progenitor cells.
    Cironi L; Riggi N; Provero P; Wolf N; Suvà ML; Suvà D; Kindler V; Stamenkovic I
    PLoS One; 2008 Jul; 3(7):e2634. PubMed ID: 18648544
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma.
    Sankar S; Bell R; Stephens B; Zhuo R; Sharma S; Bearss DJ; Lessnick SL
    Oncogene; 2013 Oct; 32(42):5089-100. PubMed ID: 23178492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PRAS40 is a functionally critical target for EWS repression in Ewing sarcoma.
    Huang L; Nakai Y; Kuwahara I; Matsumoto K
    Cancer Res; 2012 Mar; 72(5):1260-9. PubMed ID: 22241085
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.
    Boro A; Prêtre K; Rechfeld F; Thalhammer V; Oesch S; Wachtel M; Schäfer BW; Niggli FK
    Int J Cancer; 2012 Nov; 131(9):2153-64. PubMed ID: 22323082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.
    Kinsey M; Smith R; Lessnick SL
    Mol Cancer Res; 2006 Nov; 4(11):851-9. PubMed ID: 17114343
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma.
    Owen LA; Kowalewski AA; Lessnick SL
    PLoS One; 2008 Apr; 3(4):e1965. PubMed ID: 18414662
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro.
    Jully B; Vijayalakshmi R; Gopal G; Sabitha K; Rajkumar T
    BMC Cancer; 2012 Nov; 12():513. PubMed ID: 23145994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro.
    Aryee DN; Niedan S; Kauer M; Schwentner R; Bennani-Baiti IM; Ban J; Muehlbacher K; Kreppel M; Walker RL; Meltzer P; Poremba C; Kofler R; Kovar H
    Cancer Res; 2010 May; 70(10):4015-23. PubMed ID: 20442286
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growth.
    Hameiri-Grossman M; Porat-Klein A; Yaniv I; Ash S; Cohen IJ; Kodman Y; Haklai R; Elad-Sfadia G; Kloog Y; Chepurko E; Feinmesser M; Issakov J; Sher O; Luria D; Kollender Y; Weizman A; Avigad S
    Oncotarget; 2015 Oct; 6(32):33834-48. PubMed ID: 26393682
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Promiscuous partnerships in Ewing's sarcoma.
    Sankar S; Lessnick SL
    Cancer Genet; 2011 Jul; 204(7):351-65. PubMed ID: 21872822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature.
    Hancock JD; Lessnick SL
    Cell Cycle; 2008 Jan; 7(2):250-6. PubMed ID: 18256529
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model.
    González I; Vicent S; de Alava E; Lecanda F
    J Mol Med (Berl); 2007 Sep; 85(9):1015-29. PubMed ID: 17453169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma.
    Smith R; Owen LA; Trem DJ; Wong JS; Whangbo JS; Golub TR; Lessnick SL
    Cancer Cell; 2006 May; 9(5):405-16. PubMed ID: 16697960
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.