BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 2186027)

  • 1. Sensitive, soluble chromogenic substrates for HIV-1 proteinase.
    Richards AD; Phylip LH; Farmerie WG; Scarborough PE; Alvarez A; Dunn BM; Hirel PH; Konvalinka J; Strop P; Pavlickova L
    J Biol Chem; 1990 May; 265(14):7733-6. PubMed ID: 2186027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sub-site preferences of the aspartic proteinase from the human immunodeficiency virus, HIV-1.
    Konvalinka J; Strop P; Velek J; Cerna V; Kostka V; Phylip LH; Richards AD; Dunn BM; Kay J
    FEBS Lett; 1990 Jul; 268(1):35-8. PubMed ID: 2200711
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases.
    Phylip LH; Richards AD; Kay J; Kovalinka J; Strop P; Blaha I; Velek J; Kostka V; Ritchie AJ; Broadhurst AV
    Biochem Biophys Res Commun; 1990 Aug; 171(1):439-44. PubMed ID: 2203349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2.
    Tomasselli AG; Hui JO; Sawyer TK; Staples DJ; Bannow C; Reardon IM; Howe WJ; DeCamp DL; Craik CS; Heinrikson RL
    J Biol Chem; 1990 Aug; 265(24):14675-83. PubMed ID: 2201691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substitutions at the P2' site of gag p17-p24 affect cleavage efficiency by HIV-1 protease.
    Margolin N; Heath W; Osborne E; Lai M; Vlahos C
    Biochem Biophys Res Commun; 1990 Mar; 167(2):554-60. PubMed ID: 2182016
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteolytic activation of recombinant pro-memapsin 2 (pro-beta-secretase) studied with new fluorogenic substrates.
    Ermolieff J; Loy JA; Koelsch G; Tang J
    Biochemistry; 2000 Oct; 39(40):12450-6. PubMed ID: 11015226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor.
    Copeland TD; Wondrak EM; Tozser J; Roberts MM; Oroszlan S
    Biochem Biophys Res Commun; 1990 May; 169(1):310-4. PubMed ID: 2190554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The pH dependence of the hydrolysis of chromogenic substrates of the type, Lys-Pro-Xaa-Yaa-Phe-(NO2)Phe-Arg-Leu, by selected aspartic proteinases: evidence for specific interactions in subsites S3 and S2.
    Dunn BM; Valler MJ; Rolph CE; Foundling SI; Jimenez M; Kay J
    Biochim Biophys Acta; 1987 Jun; 913(2):122-30. PubMed ID: 3109484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chromophoric peptide substrates for the spectrophotometric assay of HIV-1 protease.
    Tomaszek TA; Magaard VW; Bryan HG; Moore ML; Meek TD
    Biochem Biophys Res Commun; 1990 Apr; 168(1):274-80. PubMed ID: 2183799
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase.
    Partin K; Kräusslich HG; Ehrlich L; Wimmer E; Carter C
    J Virol; 1990 Aug; 64(8):3938-47. PubMed ID: 2196384
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hydrophilic peptides derived from the transframe region of Gag-Pol inhibit the HIV-1 protease.
    Louis JM; Dyda F; Nashed NT; Kimmel AR; Davies DR
    Biochemistry; 1998 Feb; 37(8):2105-10. PubMed ID: 9485357
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increase in fluorescence upon the hydrolysis of tyrosine peptides: application to proteinase assays.
    Peranteau AG; Kuzmic P; Angell Y; García-Echeverría C; Rich DH
    Anal Biochem; 1995 May; 227(1):242-5. PubMed ID: 7668386
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exploration of subsite binding specificity of human cathepsin D through kinetics and rule-based molecular modeling.
    Scarborough PE; Guruprasad K; Topham C; Richo GR; Conner GE; Blundell TL; Dunn BM
    Protein Sci; 1993 Feb; 2(2):264-76. PubMed ID: 8443603
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro inhibition of HIV-1 proteinase by cerulenin.
    Moelling K; Schulze T; Knoop MT; Kay J; Jupp R; Nicolaou G; Pearl LH
    FEBS Lett; 1990 Feb; 261(2):373-7. PubMed ID: 1690152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays.
    Dreyer GB; Lambert DM; Meek TD; Carr TJ; Tomaszek TA; Fernandez AV; Bartus H; Cacciavillani E; Hassell AM; Minnich M
    Biochemistry; 1992 Jul; 31(29):6646-59. PubMed ID: 1637805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Subsite preferences of retroviral proteinases.
    Dunn BM; Gustchina A; Wlodawer A; Kay J
    Methods Enzymol; 1994; 241():254-78. PubMed ID: 7854181
    [No Abstract]   [Full Text] [Related]  

  • 17. Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins.
    Cameron CE; Grinde B; Jentoft J; Leis J; Weber IT; Copeland TD; Wlodawer A
    J Biol Chem; 1992 Nov; 267(33):23735-41. PubMed ID: 1331099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hydroxyethylamine analogues of the p17/p24 substrate cleavage site are tight-binding inhibitors of HIV protease.
    Rich DH; Green J; Toth MV; Marshall GR; Kent SB
    J Med Chem; 1990 May; 33(5):1285-8. PubMed ID: 2184237
    [No Abstract]   [Full Text] [Related]  

  • 19. Substrate specificities of pepstatin-insensitive carboxyl proteinases from gram-negative bacteria.
    Ito M; Dunn BM; Oda K
    J Biochem; 1996 Oct; 120(4):845-50. PubMed ID: 8947851
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro processing of HIV-1 nucleocapsid protein by the viral proteinase: effects of amino acid substitutions at the scissile bond in the proximal zinc finger sequence.
    Tözsér J; Shulenin S; Louis JM; Copeland TD; Oroszlan S
    Biochemistry; 2004 Apr; 43(14):4304-12. PubMed ID: 15065874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.