BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

504 related articles for article (PubMed ID: 21860411)

  • 1. Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
    Gaude H; Aznar N; Delay A; Bres A; Buchet-Poyau K; Caillat C; Vigouroux A; Rogon C; Woods A; Vanacker JM; Höhfeld J; Perret C; Meyer P; Billaud M; Forcet C
    Oncogene; 2012 Mar; 31(12):1582-91. PubMed ID: 21860411
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.
    Boudeau J; Deak M; Lawlor MA; Morrice NA; Alessi DR
    Biochem J; 2003 Mar; 370(Pt 3):849-57. PubMed ID: 12489981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
    Nony P; Gaude H; Rossel M; Fournier L; Rouault JP; Billaud M
    Oncogene; 2003 Dec; 22(57):9165-75. PubMed ID: 14668798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex.
    Wang Y; Xu W; Zhou D; Neckers L; Chen S
    J Biol Chem; 2014 Feb; 289(8):4815-26. PubMed ID: 24379398
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
    Ota A; Zhang J; Ping P; Han J; Wang Y
    Circ Res; 2010 Apr; 106(8):1404-12. PubMed ID: 20299663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily.
    Miyata Y; Ikawa Y; Shibuya M; Nishida E
    J Biol Chem; 2001 Jun; 276(24):21841-8. PubMed ID: 11278794
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional Role and Hierarchy of the Intermolecular Interactions in Binding of Protein Kinase Clients to the Hsp90-Cdc37 Chaperone: Structure-Based Network Modeling of Allosteric Regulation.
    Stetz G; Verkhivker GM
    J Chem Inf Model; 2018 Feb; 58(2):405-421. PubMed ID: 29432007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.
    Czemeres J; Buse K; Verkhivker GM
    PLoS One; 2017; 12(12):e0190267. PubMed ID: 29267381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleotide-Free sB-Raf is Preferentially Bound by Hsp90 and Cdc37 In Vitro.
    Eckl JM; Daake M; Schwartz S; Richter K
    J Mol Biol; 2016 Oct; 428(20):4185-4196. PubMed ID: 27620500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.
    Basso AD; Solit DB; Chiosis G; Giri B; Tsichlis P; Rosen N
    J Biol Chem; 2002 Oct; 277(42):39858-66. PubMed ID: 12176997
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone.
    Miyata Y; Nishida E
    Biochim Biophys Acta Mol Cell Res; 2021 Sep; 1868(10):119081. PubMed ID: 34147560
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
    Xu W; Mollapour M; Prodromou C; Wang S; Scroggins BT; Palchick Z; Beebe K; Siderius M; Lee MJ; Couvillon A; Trepel JB; Miyata Y; Matts R; Neckers L
    Mol Cell; 2012 Aug; 47(3):434-43. PubMed ID: 22727666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.
    Smith JR; de Billy E; Hobbs S; Powers M; Prodromou C; Pearl L; Clarke PA; Workman P
    Oncogene; 2015 Jan; 34(1):15-26. PubMed ID: 24292678
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.
    Roiniotis J; Masendycz P; Ho S; Scholz GM
    Biochemistry; 2005 May; 44(17):6662-9. PubMed ID: 15850399
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
    Li R; Yuan F; Fu W; Zhang L; Zhang N; Wang Y; Ma K; Li X; Wang L; Zhu WG; Zhao Y
    J Biol Chem; 2017 Feb; 292(7):2830-2841. PubMed ID: 28073914
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.
    Hawley SA; Boudeau J; Reid JL; Mustard KJ; Udd L; Mäkelä TP; Alessi DR; Hardie DG
    J Biol; 2003; 2(4):28. PubMed ID: 14511394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A.
    Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
    BMC Bioinformatics; 2011 Feb; 12 Suppl 1(Suppl 1):S30. PubMed ID: 21342561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90.
    Turnbull EL; Martin IV; Fantes PA
    FEBS J; 2005 Aug; 272(16):4129-40. PubMed ID: 16098195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A client-binding site of Cdc37.
    Terasawa K; Minami Y
    FEBS J; 2005 Sep; 272(18):4684-90. PubMed ID: 16156789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical and structural studies of the interaction of Cdc37 with Hsp90.
    Zhang W; Hirshberg M; McLaughlin SH; Lazar GA; Grossmann JG; Nielsen PR; Sobott F; Robinson CV; Jackson SE; Laue ED
    J Mol Biol; 2004 Jul; 340(4):891-907. PubMed ID: 15223329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.