These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

508 related articles for article (PubMed ID: 21860411)

  • 1. Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
    Gaude H; Aznar N; Delay A; Bres A; Buchet-Poyau K; Caillat C; Vigouroux A; Rogon C; Woods A; Vanacker JM; Höhfeld J; Perret C; Meyer P; Billaud M; Forcet C
    Oncogene; 2012 Mar; 31(12):1582-91. PubMed ID: 21860411
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.
    Boudeau J; Deak M; Lawlor MA; Morrice NA; Alessi DR
    Biochem J; 2003 Mar; 370(Pt 3):849-57. PubMed ID: 12489981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
    Nony P; Gaude H; Rossel M; Fournier L; Rouault JP; Billaud M
    Oncogene; 2003 Dec; 22(57):9165-75. PubMed ID: 14668798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex.
    Wang Y; Xu W; Zhou D; Neckers L; Chen S
    J Biol Chem; 2014 Feb; 289(8):4815-26. PubMed ID: 24379398
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
    Ota A; Zhang J; Ping P; Han J; Wang Y
    Circ Res; 2010 Apr; 106(8):1404-12. PubMed ID: 20299663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily.
    Miyata Y; Ikawa Y; Shibuya M; Nishida E
    J Biol Chem; 2001 Jun; 276(24):21841-8. PubMed ID: 11278794
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional Role and Hierarchy of the Intermolecular Interactions in Binding of Protein Kinase Clients to the Hsp90-Cdc37 Chaperone: Structure-Based Network Modeling of Allosteric Regulation.
    Stetz G; Verkhivker GM
    J Chem Inf Model; 2018 Feb; 58(2):405-421. PubMed ID: 29432007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.
    Czemeres J; Buse K; Verkhivker GM
    PLoS One; 2017; 12(12):e0190267. PubMed ID: 29267381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleotide-Free sB-Raf is Preferentially Bound by Hsp90 and Cdc37 In Vitro.
    Eckl JM; Daake M; Schwartz S; Richter K
    J Mol Biol; 2016 Oct; 428(20):4185-4196. PubMed ID: 27620500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.
    Basso AD; Solit DB; Chiosis G; Giri B; Tsichlis P; Rosen N
    J Biol Chem; 2002 Oct; 277(42):39858-66. PubMed ID: 12176997
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone.
    Miyata Y; Nishida E
    Biochim Biophys Acta Mol Cell Res; 2021 Sep; 1868(10):119081. PubMed ID: 34147560
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
    Xu W; Mollapour M; Prodromou C; Wang S; Scroggins BT; Palchick Z; Beebe K; Siderius M; Lee MJ; Couvillon A; Trepel JB; Miyata Y; Matts R; Neckers L
    Mol Cell; 2012 Aug; 47(3):434-43. PubMed ID: 22727666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.
    Smith JR; de Billy E; Hobbs S; Powers M; Prodromou C; Pearl L; Clarke PA; Workman P
    Oncogene; 2015 Jan; 34(1):15-26. PubMed ID: 24292678
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.
    Roiniotis J; Masendycz P; Ho S; Scholz GM
    Biochemistry; 2005 May; 44(17):6662-9. PubMed ID: 15850399
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
    Li R; Yuan F; Fu W; Zhang L; Zhang N; Wang Y; Ma K; Li X; Wang L; Zhu WG; Zhao Y
    J Biol Chem; 2017 Feb; 292(7):2830-2841. PubMed ID: 28073914
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.
    Hawley SA; Boudeau J; Reid JL; Mustard KJ; Udd L; Mäkelä TP; Alessi DR; Hardie DG
    J Biol; 2003; 2(4):28. PubMed ID: 14511394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90.
    Turnbull EL; Martin IV; Fantes PA
    FEBS J; 2005 Aug; 272(16):4129-40. PubMed ID: 16098195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A.
    Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
    BMC Bioinformatics; 2011 Feb; 12 Suppl 1(Suppl 1):S30. PubMed ID: 21342561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A client-binding site of Cdc37.
    Terasawa K; Minami Y
    FEBS J; 2005 Sep; 272(18):4684-90. PubMed ID: 16156789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical and structural studies of the interaction of Cdc37 with Hsp90.
    Zhang W; Hirshberg M; McLaughlin SH; Lazar GA; Grossmann JG; Nielsen PR; Sobott F; Robinson CV; Jackson SE; Laue ED
    J Mol Biol; 2004 Jul; 340(4):891-907. PubMed ID: 15223329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.