197 related articles for article (PubMed ID: 21861534)
1. Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation.
Szymanski DW; Papanastasiou M; Melchior K; Zvonok N; Mercier RW; Janero DR; Thakur GA; Cha S; Wu B; Karger B; Makriyannis A
J Proteome Res; 2011 Oct; 10(10):4789-98. PubMed ID: 21861534
[TBL] [Abstract][Full Text] [Related]
2. Human Cannabinoid Receptor 2 Ligand-Interaction Motif: Transmembrane Helix 2 Cysteine, C2.59(89), as Determinant of Classical Cannabinoid Agonist Activity and Binding Pose.
Zhou H; Peng Y; Halikhedkar A; Fan P; Janero DR; Thakur GA; Mercier RW; Sun X; Ma X; Makriyannis A
ACS Chem Neurosci; 2017 Jun; 8(6):1338-1347. PubMed ID: 28220706
[TBL] [Abstract][Full Text] [Related]
3. Binding Site Characterization of AM1336, a Novel Covalent Inverse Agonist at Human Cannabinoid 2 Receptor, Using Mass Spectrometric Analysis.
Mallipeddi S; Kreimer S; Zvonok N; Vemuri K; Karger BL; Ivanov AR; Makriyannis A
J Proteome Res; 2017 Jul; 16(7):2419-2428. PubMed ID: 28374590
[TBL] [Abstract][Full Text] [Related]
4. Comprehensive proteomic mass spectrometric characterization of human cannabinoid CB2 receptor.
Zvonok N; Yaddanapudi S; Williams J; Dai S; Dong K; Rejtar T; Karger BL; Makriyannis A
J Proteome Res; 2007 Jun; 6(6):2068-79. PubMed ID: 17472360
[TBL] [Abstract][Full Text] [Related]
5. Aliphatic Azides as Selective Cysteine Labeling Reagents for Integral Membrane Proteins.
Szymanski D; Papanastasiou M; Pandarinathan L; Zvonok N; Janero DR; Pavlopoulos S; Vouros P; Makriyannis A
J Med Chem; 2018 Dec; 61(24):11199-11208. PubMed ID: 30444608
[TBL] [Abstract][Full Text] [Related]
6. Ligand-Assisted Protein Structure (LAPS): An Experimental Paradigm for Characterizing Cannabinoid-Receptor Ligand-Binding Domains.
Janero DR; Korde A; Makriyannis A
Methods Enzymol; 2017; 593():217-235. PubMed ID: 28750804
[TBL] [Abstract][Full Text] [Related]
7. Mass spectrometry-based GPCR proteomics: comprehensive characterization of the human cannabinoid 1 receptor.
Zvonok N; Xu W; Williams J; Janero DR; Krishnan SC; Makriyannis A
J Proteome Res; 2010 Apr; 9(4):1746-53. PubMed ID: 20131867
[TBL] [Abstract][Full Text] [Related]
8. Purification and mass spectroscopic analysis of human CB2 cannabinoid receptor expressed in the baculovirus system.
Filppula S; Yaddanapudi S; Mercier R; Xu W; Pavlopoulos S; Makriyannis A
J Pept Res; 2004 Dec; 64(6):225-36. PubMed ID: 15613086
[TBL] [Abstract][Full Text] [Related]
9.
Gianquinto E; Sodano F; Rolando B; Kostrzewa M; Allarà M; Mahmoud AM; Kumar P; Spyrakis F; Ligresti A; Chegaev K
Molecules; 2022 Nov; 27(23):. PubMed ID: 36500256
[TBL] [Abstract][Full Text] [Related]
10. Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.
Pei Y; Mercier RW; Anday JK; Thakur GA; Zvonok AM; Hurst D; Reggio PH; Janero DR; Makriyannis A
Chem Biol; 2008 Nov; 15(11):1207-19. PubMed ID: 19022181
[TBL] [Abstract][Full Text] [Related]
11. Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments.
Tiburu EK; Tyukhtenko S; Deshmukh L; Vinogradova O; Janero DR; Makriyannis A
Biochem Biophys Res Commun; 2009 Jun; 384(2):243-8. PubMed ID: 19397896
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of G protein-coupled receptor-Gi protein interaction: formation of the cannabinoid CB2 receptor-Gi protein complex.
Mnpotra JS; Qiao Z; Cai J; Lynch DL; Grossfield A; Leioatts N; Hurst DP; Pitman MC; Song ZH; Reggio PH
J Biol Chem; 2014 Jul; 289(29):20259-72. PubMed ID: 24855641
[TBL] [Abstract][Full Text] [Related]
13. (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.
Picone RP; Khanolkar AD; Xu W; Ayotte LA; Thakur GA; Hurst DP; Abood ME; Reggio PH; Fournier DJ; Makriyannis A
Mol Pharmacol; 2005 Dec; 68(6):1623-35. PubMed ID: 16157695
[TBL] [Abstract][Full Text] [Related]
14. Purification and mass spectroscopic analysis of human CB1 cannabinoid receptor functionally expressed using the baculovirus system.
Xu W; Filppula SA; Mercier R; Yaddanapudi S; Pavlopoulos S; Cai J; Pierce WM; Makriyannis A
J Pept Res; 2005 Sep; 66(3):138-50. PubMed ID: 16083441
[TBL] [Abstract][Full Text] [Related]
15. 3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
Xie XQ; Chen JZ; Billings EM
Proteins; 2003 Nov; 53(2):307-19. PubMed ID: 14517981
[TBL] [Abstract][Full Text] [Related]
16. Fluorescein as a versatile tag for enhanced selectivity in analyzing cysteine-containing proteins/peptides using mass spectrometry.
Chen SH; Hsu JL; Lin FS
Anal Chem; 2008 Jul; 80(13):5251-9. PubMed ID: 18512949
[TBL] [Abstract][Full Text] [Related]
17. Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.
Janero DR; Yaddanapudi S; Zvonok N; Subramanian KV; Shukla VG; Stahl E; Zhou L; Hurst D; Wager-Miller J; Bohn LM; Reggio PH; Mackie K; Makriyannis A
ACS Chem Neurosci; 2015 Aug; 6(8):1400-10. PubMed ID: 25978068
[TBL] [Abstract][Full Text] [Related]
18. hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation.
Mercier RW; Pei Y; Pandarinathan L; Janero DR; Zhang J; Makriyannis A
Chem Biol; 2010 Oct; 17(10):1132-42. PubMed ID: 21035736
[TBL] [Abstract][Full Text] [Related]
19. Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52.
Ma M; Guo S; Lin X; Li S; Wu Y; Zeng Y; Hu Y; Zhao S; Xu F; Xie X; Shui W
ACS Chem Biol; 2020 Dec; 15(12):3275-3284. PubMed ID: 33258587
[TBL] [Abstract][Full Text] [Related]
20. Optimized Proteomic Mass Spectrometry Characterization of Recombinant Human μ-Opioid Receptor Functionally Expressed in Pichia pastoris Cell Lines.
Rosa M; Bech-Serra JJ; Canals F; Zajac JM; Talmont F; Arsequell G; Valencia G
J Proteome Res; 2015 Aug; 14(8):3162-73. PubMed ID: 26090583
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
