These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 21861534)

  • 1. Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation.
    Szymanski DW; Papanastasiou M; Melchior K; Zvonok N; Mercier RW; Janero DR; Thakur GA; Cha S; Wu B; Karger B; Makriyannis A
    J Proteome Res; 2011 Oct; 10(10):4789-98. PubMed ID: 21861534
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human Cannabinoid Receptor 2 Ligand-Interaction Motif: Transmembrane Helix 2 Cysteine, C2.59(89), as Determinant of Classical Cannabinoid Agonist Activity and Binding Pose.
    Zhou H; Peng Y; Halikhedkar A; Fan P; Janero DR; Thakur GA; Mercier RW; Sun X; Ma X; Makriyannis A
    ACS Chem Neurosci; 2017 Jun; 8(6):1338-1347. PubMed ID: 28220706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Binding Site Characterization of AM1336, a Novel Covalent Inverse Agonist at Human Cannabinoid 2 Receptor, Using Mass Spectrometric Analysis.
    Mallipeddi S; Kreimer S; Zvonok N; Vemuri K; Karger BL; Ivanov AR; Makriyannis A
    J Proteome Res; 2017 Jul; 16(7):2419-2428. PubMed ID: 28374590
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comprehensive proteomic mass spectrometric characterization of human cannabinoid CB2 receptor.
    Zvonok N; Yaddanapudi S; Williams J; Dai S; Dong K; Rejtar T; Karger BL; Makriyannis A
    J Proteome Res; 2007 Jun; 6(6):2068-79. PubMed ID: 17472360
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aliphatic Azides as Selective Cysteine Labeling Reagents for Integral Membrane Proteins.
    Szymanski D; Papanastasiou M; Pandarinathan L; Zvonok N; Janero DR; Pavlopoulos S; Vouros P; Makriyannis A
    J Med Chem; 2018 Dec; 61(24):11199-11208. PubMed ID: 30444608
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand-Assisted Protein Structure (LAPS): An Experimental Paradigm for Characterizing Cannabinoid-Receptor Ligand-Binding Domains.
    Janero DR; Korde A; Makriyannis A
    Methods Enzymol; 2017; 593():217-235. PubMed ID: 28750804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mass spectrometry-based GPCR proteomics: comprehensive characterization of the human cannabinoid 1 receptor.
    Zvonok N; Xu W; Williams J; Janero DR; Krishnan SC; Makriyannis A
    J Proteome Res; 2010 Apr; 9(4):1746-53. PubMed ID: 20131867
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification and mass spectroscopic analysis of human CB2 cannabinoid receptor expressed in the baculovirus system.
    Filppula S; Yaddanapudi S; Mercier R; Xu W; Pavlopoulos S; Makriyannis A
    J Pept Res; 2004 Dec; 64(6):225-36. PubMed ID: 15613086
    [TBL] [Abstract][Full Text] [Related]  

  • 9.
    Gianquinto E; Sodano F; Rolando B; Kostrzewa M; Allarà M; Mahmoud AM; Kumar P; Spyrakis F; Ligresti A; Chegaev K
    Molecules; 2022 Nov; 27(23):. PubMed ID: 36500256
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.
    Pei Y; Mercier RW; Anday JK; Thakur GA; Zvonok AM; Hurst D; Reggio PH; Janero DR; Makriyannis A
    Chem Biol; 2008 Nov; 15(11):1207-19. PubMed ID: 19022181
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments.
    Tiburu EK; Tyukhtenko S; Deshmukh L; Vinogradova O; Janero DR; Makriyannis A
    Biochem Biophys Res Commun; 2009 Jun; 384(2):243-8. PubMed ID: 19397896
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of G protein-coupled receptor-Gi protein interaction: formation of the cannabinoid CB2 receptor-Gi protein complex.
    Mnpotra JS; Qiao Z; Cai J; Lynch DL; Grossfield A; Leioatts N; Hurst DP; Pitman MC; Song ZH; Reggio PH
    J Biol Chem; 2014 Jul; 289(29):20259-72. PubMed ID: 24855641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.
    Picone RP; Khanolkar AD; Xu W; Ayotte LA; Thakur GA; Hurst DP; Abood ME; Reggio PH; Fournier DJ; Makriyannis A
    Mol Pharmacol; 2005 Dec; 68(6):1623-35. PubMed ID: 16157695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Purification and mass spectroscopic analysis of human CB1 cannabinoid receptor functionally expressed using the baculovirus system.
    Xu W; Filppula SA; Mercier R; Yaddanapudi S; Pavlopoulos S; Cai J; Pierce WM; Makriyannis A
    J Pept Res; 2005 Sep; 66(3):138-50. PubMed ID: 16083441
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
    Xie XQ; Chen JZ; Billings EM
    Proteins; 2003 Nov; 53(2):307-19. PubMed ID: 14517981
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluorescein as a versatile tag for enhanced selectivity in analyzing cysteine-containing proteins/peptides using mass spectrometry.
    Chen SH; Hsu JL; Lin FS
    Anal Chem; 2008 Jul; 80(13):5251-9. PubMed ID: 18512949
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.
    Janero DR; Yaddanapudi S; Zvonok N; Subramanian KV; Shukla VG; Stahl E; Zhou L; Hurst D; Wager-Miller J; Bohn LM; Reggio PH; Mackie K; Makriyannis A
    ACS Chem Neurosci; 2015 Aug; 6(8):1400-10. PubMed ID: 25978068
    [TBL] [Abstract][Full Text] [Related]  

  • 18. hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation.
    Mercier RW; Pei Y; Pandarinathan L; Janero DR; Zhang J; Makriyannis A
    Chem Biol; 2010 Oct; 17(10):1132-42. PubMed ID: 21035736
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52.
    Ma M; Guo S; Lin X; Li S; Wu Y; Zeng Y; Hu Y; Zhao S; Xu F; Xie X; Shui W
    ACS Chem Biol; 2020 Dec; 15(12):3275-3284. PubMed ID: 33258587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Optimized Proteomic Mass Spectrometry Characterization of Recombinant Human μ-Opioid Receptor Functionally Expressed in Pichia pastoris Cell Lines.
    Rosa M; Bech-Serra JJ; Canals F; Zajac JM; Talmont F; Arsequell G; Valencia G
    J Proteome Res; 2015 Aug; 14(8):3162-73. PubMed ID: 26090583
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.