BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 21862596)

  • 1. Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination.
    Shibata Y; Tanaka Y; Gohda J; Inoue J
    J Biochem; 2011 Dec; 150(6):679-86. PubMed ID: 21862596
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination.
    Gohda J; Irisawa M; Tanaka Y; Sato S; Ohtani K; Fujisawa J; Inoue J
    Biochem Biophys Res Commun; 2007 May; 357(1):225-30. PubMed ID: 17418100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of K63-linked polyubiquitination in NF-κB signalling: which ligase catalyzes and what molecule is targeted?
    Hayakawa M
    J Biochem; 2012 Feb; 151(2):115-8. PubMed ID: 22170213
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.
    Lamsoul I; Lodewick J; Lebrun S; Brasseur R; Burny A; Gaynor RB; Bex F
    Mol Cell Biol; 2005 Dec; 25(23):10391-406. PubMed ID: 16287853
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.
    Shibata Y; Tokunaga F; Goto E; Komatsu G; Gohda J; Saeki Y; Tanaka K; Takahashi H; Sawasaki T; Inoue S; Oshiumi H; Seya T; Nakano H; Tanaka Y; Iwai K; Inoue JI
    PLoS Pathog; 2017 Jan; 13(1):e1006162. PubMed ID: 28103322
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase.
    Harhaj NS; Sun SC; Harhaj EW
    J Biol Chem; 2007 Feb; 282(6):4185-92. PubMed ID: 17145747
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HTLV-1 Tax is a critical lipid raft modulator that hijacks IkappaB kinases to the microdomains for persistent activation of NF-kappaB.
    Huang J; Ren T; Guan H; Jiang Y; Cheng H
    J Biol Chem; 2009 Mar; 284(10):6208-17. PubMed ID: 19129196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains.
    Wang C; Long W; Peng C; Hu L; Zhang Q; Wu A; Zhang X; Duan X; Wong CC; Tanaka Y; Xia Z
    PLoS Pathog; 2016 Apr; 12(4):e1005584. PubMed ID: 27082114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein.
    Xiao G; Sun SC
    Oncogene; 2000 Oct; 19(45):5198-203. PubMed ID: 11064457
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.
    Ho YK; Zhi H; Bowlin T; Dorjbal B; Philip S; Zahoor MA; Shih HM; Semmes OJ; Schaefer B; Glover JN; Giam CZ
    PLoS Pathog; 2015 Aug; 11(8):e1005102. PubMed ID: 26285145
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation.
    Bonnet A; Randrianarison-Huetz V; Nzounza P; Nedelec M; Chazal M; Waast L; Pene S; Bazarbachi A; Mahieux R; Bénit L; Pique C
    Retrovirology; 2012 Sep; 9():77. PubMed ID: 23009398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.
    Geleziunas R; Ferrell S; Lin X; Mu Y; Cunningham ET; Grant M; Connelly MA; Hambor JE; Marcu KB; Greene WC
    Mol Cell Biol; 1998 Sep; 18(9):5157-65. PubMed ID: 9710600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK.
    Wu X; Sun SC
    EMBO Rep; 2007 May; 8(5):510-5. PubMed ID: 17363973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation.
    Hai T; Yeung ML; Wood TG; Wei Y; Yamaoka S; Gatalica Z; Jeang KT; Brasier AR
    J Virol; 2006 May; 80(9):4227-41. PubMed ID: 16611882
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome.
    Kfoury Y; Nasr R; Favre-Bonvin A; El-Sabban M; Renault N; Giron ML; Setterblad N; Hajj HE; Chiari E; Mikati AG; Hermine O; Saib A; de Thé H; Pique C; Bazarbachi A
    Oncogene; 2008 Mar; 27(12):1665-76. PubMed ID: 17891179
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of NF-kappaB by HTLV-I and implications for cell transformation.
    Sun SC; Yamaoka S
    Oncogene; 2005 Sep; 24(39):5952-64. PubMed ID: 16155602
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of I-kappaB kinase by the HTLV type 1 Tax protein: mechanistic insights into the adaptor function of IKKgamma.
    Sun SC; Harhaj EW; Xiao G; Good L
    AIDS Res Hum Retroviruses; 2000 Nov; 16(16):1591-6. PubMed ID: 11080796
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation.
    Mohanty S; Han T; Choi YB; Lavorgna A; Zhang J; Harhaj EW
    PLoS Pathog; 2020 Dec; 16(12):e1008504. PubMed ID: 33362245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of cell death in adult T-cell leukemia cells by a novel IkappaB kinase inhibitor.
    Sanda T; Asamitsu K; Ogura H; Iida S; Utsunomiya A; Ueda R; Okamoto T
    Leukemia; 2006 Apr; 20(4):590-8. PubMed ID: 16453001
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.
    Lavorgna A; Harhaj EW
    Viruses; 2014 Oct; 6(10):3925-43. PubMed ID: 25341660
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.