BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

97 related articles for article (PubMed ID: 21864700)

  • 1. In vivo efficacy of KRP-109, a novel elastase inhibitor, in a murine model of severe pneumococcal pneumonia.
    Yamada K; Yanagihara K; Araki N; Harada Y; Morinaga Y; Izumikawa K; Kakeya H; Yamamoto Y; Hasegawa H; Kohno S; Kamihira S
    Pulm Pharmacol Ther; 2011 Dec; 24(6):660-5. PubMed ID: 21864700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of specific neutrophil elastase inhibitor, sivelestat sodium hydrate, in murine model of severe pneumococcal pneumonia.
    Yanagihara K; Fukuda Y; Seki M; Izumikawa K; Miyazaki Y; Hirakata Y; Tsukamoto K; Yamada Y; Kamhira S; Kohno S
    Exp Lung Res; 2007 Mar; 33(2):71-80. PubMed ID: 17454103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia.
    Domon H; Nagai K; Maekawa T; Oda M; Yonezawa D; Takeda W; Hiyoshi T; Tamura H; Yamaguchi M; Kawabata S; Terao Y
    Front Immunol; 2018; 9():732. PubMed ID: 29922273
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of neutrophil elastase reduces lung injury and bacterial count in hamsters.
    Hagio T; Kishikawa K; Kawabata K; Tasaka S; Hashimoto S; Hasegawa N; Ishizaka A
    Pulm Pharmacol Ther; 2008 Dec; 21(6):884-91. PubMed ID: 18992355
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.
    Sakashita A; Nishimura Y; Nishiuma T; Takenaka K; Kobayashi K; Kotani Y; Yokoyama M
    Eur J Pharmacol; 2007 Sep; 571(1):62-71. PubMed ID: 17599828
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase.
    Stevens T; Ekholm K; Gränse M; Lindahl M; Kozma V; Jungar C; Ottosson T; Falk-Håkansson H; Churg A; Wright JL; Lal H; Sanfridson A
    J Pharmacol Exp Ther; 2011 Oct; 339(1):313-20. PubMed ID: 21791628
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice.
    Fujino N; Kubo H; Suzuki T; He M; Suzuki T; Yamada M; Takahashi T; Ota C; Yamaya M
    Exp Lung Res; 2012 Feb; 38(1):28-36. PubMed ID: 22148910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Delayed neutrophil elastase inhibition prevents subsequent progression of acute lung injury induced by endotoxin inhalation in hamsters.
    Kawabata K; Hagio T; Matsumoto S; Nakao S; Orita S; Aze Y; Ohno H
    Am J Respir Crit Care Med; 2000 Jun; 161(6):2013-8. PubMed ID: 10852782
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Integrin β3 is not critical for neutrophil recruitment in a mouse model of pneumococcal pneumonia.
    Janardhan KS; Charavaryamath C; Aulakh GK; Singh B
    Cell Tissue Res; 2012 Apr; 348(1):177-87. PubMed ID: 22350844
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired pulmonary inflammatory responses are a prominent feature of streptococcal pneumonia in mice with experimental emphysema.
    Inoue S; Nakamura H; Otake K; Saito H; Terashita K; Sato J; Takeda H; Tomoike H
    Am J Respir Crit Care Med; 2003 Mar; 167(5):764-70. PubMed ID: 12598218
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vivo efficacy of sivelestat in combination with pazufloxacin against Legionella pneumonia.
    Morinaga Y; Yanagihara K; Araki N; Yamada K; Seki M; Izumikawa K; Kakeya H; Yamamoto Y; Yamada Y; Kohno S; Kamihira S
    Exp Lung Res; 2010 Oct; 36(8):484-90. PubMed ID: 20939755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of a neutrophil elastase inhibitor (ONO-5046) on acute pulmonary injury induced by tumor necrosis factor alpha (TNFalpha) and activated neutrophils in isolated perfused rabbit lungs.
    Miyazaki Y; Inoue T; Kyi M; Sawada M; Miyake S; Yoshizawa Y
    Am J Respir Crit Care Med; 1998 Jan; 157(1):89-94. PubMed ID: 9445283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Pretreatment of acid-induced lung injury with specific neutrophil elastase inhibitor ONO-5046 did not exasperate the subsequent bacterial lung infection by Pseudomonas aeruginosa].
    Kudoh I; Miyazaki H; Yamada H; Fujimoto J; Ohara M; Tazawa T; Fukushima J; Okumura F
    Masui; 2000 Jul; 49(7):724-31. PubMed ID: 10933021
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury.
    Sakamaki F; Ishizaka A; Urano T; Sayama K; Nakamura H; Terashima T; Waki Y; Tasaka S; Hasegawa N; Sato K; Nakagawa N; Obata T; Kanazawa M
    Am J Respir Crit Care Med; 1996 Jan; 153(1):391-7. PubMed ID: 8542148
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice.
    de Stoppelaar SF; Van't Veer C; van den Boogaard FE; Nieuwland R; Hoogendijk AJ; de Boer OJ; Roelofs JJ; van der Poll T
    Thromb Haemost; 2013 Sep; 110(3):582-92. PubMed ID: 23783078
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increase of apoptosis in a murine model for severe pneumococcal pneumonia during influenza A virus infection.
    Kosai K; Seki M; Tanaka A; Morinaga Y; Imamura Y; Izumikawa K; Kakeya H; Yamamoto Y; Yanagihara K; Tomono K; Kohno S
    Jpn J Infect Dis; 2011; 64(6):451-7. PubMed ID: 22116322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis.
    Song JS; Kang CM; Rhee CK; Yoon HK; Kim YK; Moon HS; Park SH
    Exp Lung Res; 2009 Dec; 35(10):817-29. PubMed ID: 19995276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roxithromycin favorably modifies the initial phase of resistance against infection with macrolide-resistant Streptococcus pneumoniae in a murine pneumonia model.
    Yasuda Y; Kasahara K; Mizuno F; Nishi K; Mikasa K; Kita E
    Antimicrob Agents Chemother; 2007 May; 51(5):1741-52. PubMed ID: 17353244
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice.
    Takemasa A; Ishii Y; Fukuda T
    Eur Respir J; 2012 Dec; 40(6):1475-82. PubMed ID: 22441751
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia.
    Knapp S; Hareng L; Rijneveld AW; Bresser P; van der Zee JS; Florquin S; Hartung T; van der Poll T
    J Infect Dis; 2004 Apr; 189(8):1506-15. PubMed ID: 15073689
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.