160 related articles for article (PubMed ID: 21866394)
1. Increasing the activity of copper(II) complexes against Leishmania through lipophilicity and pro-oxidant ability.
Portas Ados S; Miguel DC; Yokoyama-Yasunaka JK; Uliana SR; Espósito BP
J Biol Inorg Chem; 2012 Jan; 17(1):107-12. PubMed ID: 21866394
[TBL] [Abstract][Full Text] [Related]
2.
Matadamas-Martínez F; Hernández-Campos A; Téllez-Valencia A; Vázquez-Raygoza A; Comparán-Alarcón S; Yépez-Mulia L; Castillo R
Molecules; 2019 Sep; 24(18):. PubMed ID: 31487860
[TBL] [Abstract][Full Text] [Related]
3. Trypanothione reductase activity is prominent in metacyclic promastigotes and axenic amastigotes of Leishmania amazonesis. Evaluation of its potential as a therapeutic target.
Castro-Pinto DB; Echevarria A; Genestra MS; Cysne-Finkelstein L; Leon LL
J Enzyme Inhib Med Chem; 2004 Feb; 19(1):57-63. PubMed ID: 15202494
[TBL] [Abstract][Full Text] [Related]
4. New iminodibenzyl derivatives with anti-leishmanial activity.
Arndt A; Liria CW; Yokoyama-Yasunaka JKU; Machini MT; Uliana SRB; Espósito BP
J Inorg Biochem; 2017 Jul; 172():9-15. PubMed ID: 28414928
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis.
Nowicki MW; Tulloch LB; Worralll L; McNae IW; Hannaert V; Michels PA; Fothergill-Gilmore LA; Walkinshaw MD; Turner NJ
Bioorg Med Chem; 2008 May; 16(9):5050-61. PubMed ID: 18387804
[TBL] [Abstract][Full Text] [Related]
6. Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase.
de Lucio H; García-Marín J; Sánchez-Alonso P; García-Soriano JC; Toro MÁ; Vaquero JJ; Gago F; Alajarín R; Jiménez-Ruiz A
Eur J Med Chem; 2022 Jan; 227():113915. PubMed ID: 34695777
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of a new series of 3,5-disubstituted isoxazoles active against Trypanosoma cruzi and Leishmania amazonensis.
da Rosa R; de Moraes MH; Zimmermann LA; Schenkel EP; Steindel M; Bernardes LSC
Eur J Med Chem; 2017 Mar; 128():25-35. PubMed ID: 28152426
[TBL] [Abstract][Full Text] [Related]
8. Inhibitory effect of phenothiazine- and phenoxazine-derived chloroacetamides on Leishmania major growth and Trypanosoma brucei trypanothione reductase.
Marcu A; Schurigt U; Müller K; Moll H; Krauth-Siegel RL; Prinz H
Eur J Med Chem; 2016 Jan; 108():436-443. PubMed ID: 26708110
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and evaluation against Leishmania amazonensis of novel pyrazolo[3,4-d]pyridazinone-N-acylhydrazone-(bi)thiophene hybrids.
Jacomini AP; Silva MJV; Silva RGM; Gonçalves DS; Volpato H; Basso EA; Paula FR; Nakamura CV; Sarragiotto MH; Rosa FA
Eur J Med Chem; 2016 Nov; 124():340-349. PubMed ID: 27597410
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, characterization, DNA binding study and biological activity against Leishmania mexicana of [Cu(dppz)2]BF4.
Navarro M; Cisneros-Fajardo EJ; Fernandez-Mestre M; Arrieche D; Marchan E
J Inorg Biochem; 2003 Dec; 97(4):364-9. PubMed ID: 14568241
[TBL] [Abstract][Full Text] [Related]
11. In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis.
Paladi Cde S; Pimentel IA; Katz S; Cunha RL; Judice WA; Caires AC; Barbiéri CL
PLoS Negl Trop Dis; 2012; 6(5):e1626. PubMed ID: 22616018
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of plumbagin and its derivative as potential modulators of redox thiol metabolism of Leishmania parasite.
Sharma N; Shukla AK; Das M; Dubey VK
Parasitol Res; 2012 Jan; 110(1):341-8. PubMed ID: 21717278
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography.
Baiocco P; Poce G; Alfonso S; Cocozza M; Porretta GC; Colotti G; Biava M; Moraca F; Botta M; Yardley V; Fiorillo A; Lantella A; Malatesta F; Ilari A
ChemMedChem; 2013 Jul; 8(7):1175-83. PubMed ID: 23733388
[TBL] [Abstract][Full Text] [Related]
14. Metal-based compounds as prospective antileishmanial agents: inhibition of trypanothione reductase by selected gold complexes.
Colotti G; Ilari A; Fiorillo A; Baiocco P; Cinellu MA; Maiore L; Scaletti F; Gabbiani C; Messori L
ChemMedChem; 2013 Oct; 8(10):1634-7. PubMed ID: 24039168
[TBL] [Abstract][Full Text] [Related]
15. Identification of chalcone-based antileishmanial agents targeting trypanothione reductase.
Ortalli M; Ilari A; Colotti G; De Ionna I; Battista T; Bisi A; Gobbi S; Rampa A; Di Martino RMC; Gentilomi GA; Varani S; Belluti F
Eur J Med Chem; 2018 May; 152():527-541. PubMed ID: 29758517
[TBL] [Abstract][Full Text] [Related]
16. The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.
Galarreta BC; Sifuentes R; Carrillo AK; Sanchez L; Amado Mdel R; Maruenda H
Bioorg Med Chem; 2008 Jul; 16(14):6689-95. PubMed ID: 18558492
[TBL] [Abstract][Full Text] [Related]
17. Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.
De Gasparo R; Brodbeck-Persch E; Bryson S; Hentzen NB; Kaiser M; Pai EF; Krauth-Siegel RL; Diederich F
ChemMedChem; 2018 May; 13(9):957-967. PubMed ID: 29624890
[TBL] [Abstract][Full Text] [Related]
18. 2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
Salmon-Chemin L; Buisine E; Yardley V; Kohler S; Debreu MA; Landry V; Sergheraert C; Croft SL; Krauth-Siegel RL; Davioud-Charvet E
J Med Chem; 2001 Feb; 44(4):548-65. PubMed ID: 11170645
[TBL] [Abstract][Full Text] [Related]
19. Antileishmanial activity and trypanothione reductase effects of terpenes from the Amazonian species Croton cajucara Benth (Euphorbiaceae).
Lima GS; Castro-Pinto DB; Machado GC; Maciel MA; Echevarria A
Phytomedicine; 2015 Nov; 22(12):1133-7. PubMed ID: 26547537
[TBL] [Abstract][Full Text] [Related]
20. Thiol redox biology of trypanosomatids and potential targets for chemotherapy.
Leroux AE; Krauth-Siegel RL
Mol Biochem Parasitol; 2016; 206(1-2):67-74. PubMed ID: 26592324
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]