These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

101 related articles for article (PubMed ID: 21867687)

  • 21. GZD824 Inhibits GCN2 and Sensitizes Cancer Cells to Amino Acid Starvation Stress.
    Kato Y; Kunimasa K; Takahashi M; Harada A; Nagasawa I; Osawa M; Sugimoto Y; Tomida A
    Mol Pharmacol; 2020 Dec; 98(6):669-676. PubMed ID: 33033108
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Control of mammalian gene expression by amino acids, especially glutamine.
    Brasse-Lagnel C; Lavoinne A; Husson A
    FEBS J; 2009 Apr; 276(7):1826-44. PubMed ID: 19250320
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Regulation of asparagine synthetase gene transcription by the basic region leucine zipper transcription factors ATF5 and CHOP.
    Al Sarraj J; Vinson C; Thiel G
    Biol Chem; 2005 Sep; 386(9):873-9. PubMed ID: 16164412
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Induction of IGFBP-1 expression by amino acid deprivation of HepG2 human hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3'UTR.
    Averous J; Maurin AC; Bruhat A; Jousse C; Arliguie C; Fafournoux P
    FEBS Lett; 2005 May; 579(12):2609-14. PubMed ID: 15862298
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The murine p8 gene promoter is activated by activating transcription factor 4 (ATF4) in the gonadotrope-derived LbetaT2 cell line.
    Passe CM; Cooper G; Quirk CC
    Endocrine; 2006 Aug; 30(1):81-91. PubMed ID: 17185796
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.
    Ye J; Kumanova M; Hart LS; Sloane K; Zhang H; De Panis DN; Bobrovnikova-Marjon E; Diehl JA; Ron D; Koumenis C
    EMBO J; 2010 Jun; 29(12):2082-96. PubMed ID: 20473272
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Regulation of the human CHOP gene promoter by the stress response transcription factor ATF5 via the AARE1 site in human hepatoma HepG2 cells.
    Yamazaki T; Ohmi A; Kurumaya H; Kato K; Abe T; Yamamoto H; Nakanishi N; Okuyama R; Umemura M; Kaise T; Watanabe R; Okawa Y; Takahashi S; Takahashi Y
    Life Sci; 2010 Aug; 87(9-10):294-301. PubMed ID: 20654631
    [TBL] [Abstract][Full Text] [Related]  

  • 28. v-Jun represses c-jun proto-oncogene expression in vivo through a 12-O-tetradecanoylphorbol-13-acetate-responsive element in the proximal gene promoter.
    Hussain S; Kilbey A; Gillespie DA
    Cell Growth Differ; 1998 Aug; 9(8):677-86. PubMed ID: 9716184
    [TBL] [Abstract][Full Text] [Related]  

  • 29. L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport.
    Peyrollier K; Hajduch E; Blair AS; Hyde R; Hundal HS
    Biochem J; 2000 Sep; 350 Pt 2(Pt 2):361-8. PubMed ID: 10947949
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Amino acid restriction induces a long non-coding RNA UBA6-AS1 to regulate GCN2-mediated integrated stress response in breast cancer.
    Wu YZ; Chen YH; Cheng CT; Ann DK; Kuo CY
    FASEB J; 2022 Mar; 36(3):e22201. PubMed ID: 35137449
    [TBL] [Abstract][Full Text] [Related]  

  • 31. ATF4 differentially regulates transcriptional activation of myeloid-specific genes by C/EBPepsilon and C/EBPalpha.
    Gombart AF; Grewal J; Koeffler HP
    J Leukoc Biol; 2007 Jun; 81(6):1535-47. PubMed ID: 17347301
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of amino acid response element of SLC38A9 as an ATF4-binding site in porcine skeletal muscle cells.
    Wang D; Guo C; Wan X; Guo K; Niu H; Zheng R; Chai J; Jiang S
    Biochem Biophys Res Commun; 2021 Sep; 569():167-173. PubMed ID: 34246831
    [TBL] [Abstract][Full Text] [Related]  

  • 33. ATF4-dependent transcription mediates signaling of amino acid limitation.
    Kilberg MS; Shan J; Su N
    Trends Endocrinol Metab; 2009 Nov; 20(9):436-43. PubMed ID: 19800252
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Insulin signaling and the general amino acid control response. Two distinct pathways to amino acid synthesis and uptake.
    Malmberg SE; Adams CM
    J Biol Chem; 2008 Jul; 283(28):19229-34. PubMed ID: 18480057
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.
    Yuan F; Jiang H; Yin H; Jiang X; Jiao F; Chen S; Ying H; Chen Y; Zhai Q; Guo F
    Nat Commun; 2020 Jun; 11(1):2847. PubMed ID: 32504036
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.
    Toboz P; Amiri M; Tabatabaei N; Dufour CR; Kim SH; Fillebeen C; Ayemoba CE; Khoutorsky A; Nairz M; Shao L; Pajcini KV; Kim KW; Giguère V; Oliveira RL; Constante M; Santos MM; Morales CR; Pantopoulos K; Sonenberg N; Pinho S; Tahmasebi S
    Proc Natl Acad Sci U S A; 2022 Aug; 119(35):e2121251119. PubMed ID: 35994670
    [TBL] [Abstract][Full Text] [Related]  

  • 37. MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.
    Shan J; Donelan W; Hayner JN; Zhang F; Dudenhausen EE; Kilberg MS
    Biochim Biophys Acta; 2015 Mar; 1853(3):539-48. PubMed ID: 25523140
    [TBL] [Abstract][Full Text] [Related]  

  • 38. CDK7 is a component of the integrated stress response regulating SNAT2 (SLC38A2)/System A adaptation in response to cellular amino acid deprivation.
    Stretton C; Lipina C; Hyde R; Cwiklinski E; Hoffmann TM; Taylor PM; Hundal HS
    Biochim Biophys Acta Mol Cell Res; 2019 Jun; 1866(6):978-991. PubMed ID: 30857869
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Specificity of amino acid regulated gene expression: analysis of genes subjected to either complete or single amino acid deprivation.
    Palii SS; Kays CE; Deval C; Bruhat A; Fafournoux P; Kilberg MS
    Amino Acids; 2009 May; 37(1):79-88. PubMed ID: 19009228
    [TBL] [Abstract][Full Text] [Related]  

  • 40. HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway.
    Lee JI; Dominy JE; Sikalidis AK; Hirschberger LL; Wang W; Stipanuk MH
    Physiol Genomics; 2008 Apr; 33(2):218-29. PubMed ID: 18285520
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.