BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 21868511)

  • 1. 6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.
    Johnson RW; Merkel AR; Danilin S; Nguyen MP; Mundy GR; Sterling JA
    Anticancer Res; 2011 Sep; 31(9):2705-12. PubMed ID: 21868511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.
    Johnson RW; Merkel AR; Page JM; Ruppender NS; Guelcher SA; Sterling JA
    Clin Exp Metastasis; 2014 Dec; 31(8):945-59. PubMed ID: 25359619
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells.
    Sterling JA; Oyajobi BO; Grubbs B; Padalecki SS; Munoz SA; Gupta A; Story B; Zhao M; Mundy GR
    Cancer Res; 2006 Aug; 66(15):7548-53. PubMed ID: 16885353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling.
    Johnson RW; Nguyen MP; Padalecki SS; Grubbs BG; Merkel AR; Oyajobi BO; Matrisian LM; Mundy GR; Sterling JA
    Cancer Res; 2011 Feb; 71(3):822-31. PubMed ID: 21189326
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma.
    Cannonier SA; Gonzales CB; Ely K; Guelcher SA; Sterling JA
    Oncotarget; 2016 Nov; 7(46):76062-76075. PubMed ID: 27738315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin β3 and TGF-β receptor type II.
    Page JM; Merkel AR; Ruppender NS; Guo R; Dadwal UC; Cannonier S; Basu S; Guelcher SA; Sterling JA
    Biomaterials; 2015 Sep; 64():33-44. PubMed ID: 26115412
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GLI2-mediated melanoma invasion and metastasis.
    Alexaki VI; Javelaud D; Van Kempen LC; Mohammad KS; Dennler S; Luciani F; Hoek KS; Juàrez P; Goydos JS; Fournier PJ; Sibon C; Bertolotto C; Verrecchia F; Saule S; Delmas V; Ballotti R; Larue L; Saiag P; Guise TA; Mauviel A
    J Natl Cancer Inst; 2010 Aug; 102(15):1148-59. PubMed ID: 20660365
    [TBL] [Abstract][Full Text] [Related]  

  • 8. shRNA-mediated silencing of Gli2 gene inhibits proliferation and sensitizes human hepatocellular carcinoma cells towards TRAIL-induced apoptosis.
    Zhang D; Liu J; Wang Y; Chen J; Chen T
    J Cell Biochem; 2011 Nov; 112(11):3140-50. PubMed ID: 21695716
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression.
    Hastings RH; Burton DW; Nefzi A; Montgrain PR; Quintana R; Deftos LJ
    Cancer Biol Ther; 2010 Nov; 10(10):1067-75. PubMed ID: 20890111
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein.
    Amano K; Hata K; Sugita A; Takigawa Y; Ono K; Wakabayashi M; Kogo M; Nishimura R; Yoneda T
    Mol Biol Cell; 2009 Nov; 20(21):4541-51. PubMed ID: 19759178
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation.
    Dennler S; André J; Verrecchia F; Mauviel A
    J Biol Chem; 2009 Nov; 284(46):31523-31. PubMed ID: 19797115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.
    Vanderburgh JP; Kwakwa KA; Werfel TA; Merkel AR; Gupta MK; Johnson RW; Guelcher SA; Duvall CL; Rhoades JA
    J Control Release; 2019 Oct; 311-312():257-272. PubMed ID: 31494183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Parathyroid hormone-related peptide regulates matrix metalloproteinase-13 gene expression in bone metastatic breast cancer cells.
    Ibaragi S; Shimo T; Iwamoto M; Hassan NM; Kodama S; Isowa S; Sasaki A
    Anticancer Res; 2010 Dec; 30(12):5029-36. PubMed ID: 21187486
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transforming growth factor beta regulates parathyroid hormone-related protein expression in MDA-MB-231 breast cancer cells through a novel Smad/Ets synergism.
    Lindemann RK; Ballschmieter P; Nordheim A; Dittmer J
    J Biol Chem; 2001 Dec; 276(49):46661-70. PubMed ID: 11590145
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells.
    Pratap J; Wixted JJ; Gaur T; Zaidi SK; Dobson J; Gokul KD; Hussain S; van Wijnen AJ; Stein JL; Stein GS; Lian JB
    Cancer Res; 2008 Oct; 68(19):7795-802. PubMed ID: 18829534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gli2 expression and human bladder transitional carcinoma cell invasiveness.
    Mechlin CW; Tanner MJ; Chen M; Buttyan R; Levin RM; Mian BM
    J Urol; 2010 Jul; 184(1):344-51. PubMed ID: 20488474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Long noncoding RNA BCAR4 promotes osteosarcoma progression through activating GLI2-dependent gene transcription.
    Chen F; Mo J; Zhang L
    Tumour Biol; 2016 Oct; 37(10):13403-13412. PubMed ID: 27460090
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.
    Mau E; Whetstone H; Yu C; Hopyan S; Wunder JS; Alman BA
    Dev Biol; 2007 May; 305(1):28-39. PubMed ID: 17328886
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion.
    Nagao-Kitamoto H; Setoguchi T; Kitamoto S; Nakamura S; Tsuru A; Nagata M; Nagano S; Ishidou Y; Yokouchi M; Kitajima S; Yoshioka T; Maeda S; Yonezawa S; Komiya S
    Cancer Lett; 2015 Jan; 356(2 Pt B):855-61. PubMed ID: 25449781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells.
    Gilmore JL; Scott JA; Bouizar Z; Robling A; Pitfield SE; Riese DJ; Foley J
    Breast Cancer Res Treat; 2008 Aug; 110(3):493-505. PubMed ID: 17882547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.