These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 21868755)

  • 1. Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.
    Chen S; Cao W; Yue P; Hao C; Khuri FR; Sun SY
    Cancer Res; 2011 Oct; 71(19):6270-81. PubMed ID: 21868755
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S; Liu X; Yue P; Schönthal AH; Khuri FR; Sun SY
    Mol Pharmacol; 2007 Nov; 72(5):1269-79. PubMed ID: 17684158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.
    Liu X; Yue P; Schönthal AH; Khuri FR; Sun SY
    Cancer Res; 2006 Dec; 66(23):11115-9. PubMed ID: 17145853
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling.
    Kim N; Kim CH; Ahn DW; Lee KS; Cho SJ; Park JH; Lee MK; Kim JS; Jung HC; Song IS
    J Gastroenterol Hepatol; 2009 Mar; 24(3):480-7. PubMed ID: 18823436
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages.
    Shi B; Tran T; Sobkoviak R; Pope RM
    J Biol Chem; 2009 May; 284(21):14513-23. PubMed ID: 19339247
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition.
    Li B; Ren H; Yue P; Chen M; Khuri FR; Sun SY
    Cancer Prev Res (Phila); 2012 Apr; 5(4):612-20. PubMed ID: 22345097
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells.
    Song X; Kim SY; Zhou Z; Lagasse E; Kwon YT; Lee YJ
    Cell Death Dis; 2013 Apr; 4(4):e577. PubMed ID: 23559011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced apoptotic effects by downregulating Mcl-1: evidence for the improvement of photodynamic therapy with Celecoxib.
    Song J; Chen Q; Xing D
    Exp Cell Res; 2013 Jun; 319(10):1491-504. PubMed ID: 23524145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein.
    Wilkie-Grantham RP; Matsuzawa S; Reed JC
    J Biol Chem; 2013 May; 288(18):12777-90. PubMed ID: 23519470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in premalignant human bronchial epithelial cells.
    Schroeder CP; Kadara H; Lotan D; Woo JK; Lee HY; Hong WK; Lotan R
    Cancer Res; 2006 Oct; 66(19):9762-70. PubMed ID: 17018636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.
    Le Clorennec C; Lazrek Y; Dubreuil O; Sampaio C; Larbouret C; Lanotte R; Poul MA; Barret JM; Prost JF; Pèlegrin A; Chardès T
    Cell Commun Signal; 2019 Aug; 17(1):106. PubMed ID: 31443721
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum- and glucocorticoid-induced protein kinase and Akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor cells.
    Failor KL; Desyatnikov Y; Finger LA; Firestone GL
    Mol Endocrinol; 2007 Oct; 21(10):2403-15. PubMed ID: 17595317
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of cyclooxygenase-2 in human HepG2, Bel-7402 and SMMC-7721 hepatoma cell lines and mechanism of cyclooxygenase-2 selective inhibitor celecoxib-induced cell growth inhibition and apoptosis.
    Liu NB; Peng T; Pan C; Yao YY; Shen B; Leng J
    World J Gastroenterol; 2005 Oct; 11(40):6281-7. PubMed ID: 16419156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2.
    Hsu AL; Ching TT; Wang DS; Song X; Rangnekar VM; Chen CS
    J Biol Chem; 2000 Apr; 275(15):11397-403. PubMed ID: 10753955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells.
    Panka DJ; Mano T; Suhara T; Walsh K; Mier JW
    J Biol Chem; 2001 Mar; 276(10):6893-6. PubMed ID: 11145953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer.
    Tuynman JB; Vermeulen L; Boon EM; Kemper K; Zwinderman AH; Peppelenbosch MP; Richel DJ
    Cancer Res; 2008 Feb; 68(4):1213-20. PubMed ID: 18281498
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
    Shishodia S; Koul D; Aggarwal BB
    J Immunol; 2004 Aug; 173(3):2011-22. PubMed ID: 15265936
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
    Raja SM; Chen S; Yue P; Acker TM; Lefkove B; Arbiser JL; Khuri FR; Sun SY
    Mol Cancer Ther; 2008 Jul; 7(7):2212-23. PubMed ID: 18645030
    [TBL] [Abstract][Full Text] [Related]  

  • 19. c-FLIPL enhances anti-apoptotic Akt functions by modulation of Gsk3β activity.
    Quintavalle C; Incoronato M; Puca L; Acunzo M; Zanca C; Romano G; Garofalo M; Iaboni M; Croce CM; Condorelli G
    Cell Death Differ; 2010 Dec; 17(12):1908-16. PubMed ID: 20508645
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein.
    Abedini MR; Muller EJ; Bergeron R; Gray DA; Tsang BK
    Oncogene; 2010 Jan; 29(1):11-25. PubMed ID: 19802016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.