524 related articles for article (PubMed ID: 21869830)
1. Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction.
Ryu JH; Shin Y; Huh YH; Yang S; Chun CH; Chun JS
Cell Death Differ; 2012 Mar; 19(3):440-50. PubMed ID: 21869830
[TBL] [Abstract][Full Text] [Related]
2. Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice.
Ryu JH; Yang S; Shin Y; Rhee J; Chun CH; Chun JS
Arthritis Rheum; 2011 Sep; 63(9):2732-43. PubMed ID: 21590680
[TBL] [Abstract][Full Text] [Related]
3. NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
Yang S; Ryu JH; Oh H; Jeon J; Kwak JS; Kim JH; Kim HA; Chun CH; Chun JS
Ann Rheum Dis; 2015 Mar; 74(3):595-602. PubMed ID: 24347567
[TBL] [Abstract][Full Text] [Related]
4. Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis.
Lee M; Won Y; Shin Y; Kim JH; Chun JS
Osteoarthritis Cartilage; 2016 Jan; 24(1):134-45. PubMed ID: 26241779
[TBL] [Abstract][Full Text] [Related]
5. Chemically modified curcumin (CMC2.24) alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis.
Zhou Y; Ming J; Deng M; Li Y; Li B; Li J; Ma Y; Chen Z; Wang G; Liu S
J Mol Med (Berl); 2020 Oct; 98(10):1479-1491. PubMed ID: 32860098
[TBL] [Abstract][Full Text] [Related]
6. Peptides from Antarctic Krill ( Euphausia superba) Improve Osteoarthritis via Inhibiting HIF-2α-Mediated Death Receptor Apoptosis and Metabolism Regulation in Osteoarthritic Mice.
Wang K; Li Y; Dai Y; Han L; Zhu Y; Xue C; Wang P; Wang J
J Agric Food Chem; 2019 Mar; 67(11):3125-3133. PubMed ID: 30798606
[TBL] [Abstract][Full Text] [Related]
7. Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction.
Yang S; Kim J; Ryu JH; Oh H; Chun CH; Kim BJ; Min BH; Chun JS
Nat Med; 2010 Jun; 16(6):687-93. PubMed ID: 20495569
[TBL] [Abstract][Full Text] [Related]
8. Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD(+)-SIRT axis in articular chondrocytes is involved in osteoarthritis.
Oh H; Kwak JS; Yang S; Gong MK; Kim JH; Rhee J; Kim SK; Kim HE; Ryu JH; Chun JS
Osteoarthritis Cartilage; 2015 Dec; 23(12):2288-2296. PubMed ID: 26209889
[TBL] [Abstract][Full Text] [Related]
9. Upregulation of Atrogin-1/FBXO32 is not necessary for cartilage destruction in mouse models of osteoarthritis.
Kim HE; Rhee J; Park S; Yang J; Chun JS
Osteoarthritis Cartilage; 2017 Mar; 25(3):397-400. PubMed ID: 27480933
[TBL] [Abstract][Full Text] [Related]
10. Upregulation of lipocalin-2 (LCN2) in osteoarthritic cartilage is not necessary for cartilage destruction in mice.
Choi WS; Chun JS
Osteoarthritis Cartilage; 2017 Mar; 25(3):401-405. PubMed ID: 27477830
[TBL] [Abstract][Full Text] [Related]
11. Role of HIF-1α and HIF-2α in osteoarthritis.
Zhang FJ; Luo W; Lei GH
Joint Bone Spine; 2015 May; 82(3):144-7. PubMed ID: 25553838
[TBL] [Abstract][Full Text] [Related]
12. Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis.
Won Y; Shin Y; Chun CH; Cho Y; Ha CW; Kim JH; Chun JS
Ann Rheum Dis; 2016 Nov; 75(11):2045-2052. PubMed ID: 26903440
[TBL] [Abstract][Full Text] [Related]
13. Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice.
Oh H; Chun CH; Chun JS
Arthritis Rheum; 2012 Aug; 64(8):2568-78. PubMed ID: 22488261
[TBL] [Abstract][Full Text] [Related]
14. Intra-articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF-2α.
Li W; Cai L; Zhang Y; Cui L; Shen G
J Orthop Res; 2015 Jul; 33(7):1061-70. PubMed ID: 25737402
[TBL] [Abstract][Full Text] [Related]
15. Mithramycin A Alleviates Osteoarthritic Cartilage Destruction by Inhibiting HIF-2α Expression.
Choi MC; Choi WH
Int J Mol Sci; 2018 May; 19(5):. PubMed ID: 29747385
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of syndecan-4 reduces cartilage degradation in murine models of osteoarthritis through the downregulation of HIF-2α by miR-96-5p.
Zhou K; He S; Yu H; Pei F; Zhou Z
Lab Invest; 2021 Aug; 101(8):1060-1070. PubMed ID: 33850295
[TBL] [Abstract][Full Text] [Related]
17. D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner.
Zhou X; Zheng Y; Sun W; Zhang Z; Liu J; Yang W; Yuan W; Yi Y; Wang J; Liu J
Cell Prolif; 2021 Nov; 54(11):e13134. PubMed ID: 34561933
[TBL] [Abstract][Full Text] [Related]
18. Intra-articular delivery of anti-Hif-2α siRNA by chondrocyte-homing nanoparticles to prevent cartilage degeneration in arthritic mice.
Pi Y; Zhang X; Shao Z; Zhao F; Hu X; Ao Y
Gene Ther; 2015 Jun; 22(6):439-48. PubMed ID: 25876463
[TBL] [Abstract][Full Text] [Related]
19. Overexpression of secretory leukocyte peptidase inhibitor (SLPI) does not modulate experimental osteoarthritis but may be a biomarker for the disease.
Kim HE; Shin Y; Jung IJ; Yang JI; Chun CH; Kim HA; Chun JS
Osteoarthritis Cartilage; 2021 Apr; 29(4):558-567. PubMed ID: 33485930
[TBL] [Abstract][Full Text] [Related]
20. Up-regulated HIF-2α contributes to the Osteoarthritis development through mediating the primary cilia loss.
Yang Q; Zhou Y; Cai P; Fu W; Wang J; Wei Q; Li X
Int Immunopharmacol; 2019 Oct; 75():105762. PubMed ID: 31357086
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
