BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 21873424)

  • 1. BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).
    Kilger E; Buehler A; Woelfing H; Kumar S; Kaeser SA; Nagarathinam A; Walter J; Jucker M; Coomaraswamy J
    J Biol Chem; 2011 Oct; 286(43):37446-57. PubMed ID: 21873424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Accumulation of BRI2-BRICHOS ectodomain correlates with a decreased clearance of Aβ by insulin degrading enzyme (IDE) in Alzheimer's disease.
    Del Campo M; Stargardt A; Veerhuis R; Reits E; Teunissen CE
    Neurosci Lett; 2015 Mar; 589():47-51. PubMed ID: 25597881
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Normal cognition in transgenic BRI2-Aβ mice.
    Kim J; Chakrabarty P; Hanna A; March A; Dickson DW; Borchelt DR; Golde T; Janus C
    Mol Neurodegener; 2013 May; 8():15. PubMed ID: 23663320
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical traits of cerebral amyloid angiopathy in familial British-, Danish-, and non-Alzheimer's dementias.
    Michno W; Koutarapu S; Camacho R; Toomey C; Stringer K; Minta K; Ge J; Jha D; Fernandez-Rodriguez J; Brinkmalm G; Zetterberg H; Blennow K; Ryan NS; Lashley T; Hanrieder J
    J Neurochem; 2022 Nov; 163(3):233-246. PubMed ID: 36102248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BRI2 (ITM2b) inhibits Abeta deposition in vivo.
    Kim J; Miller VM; Levites Y; West KJ; Zwizinski CW; Moore BD; Troendle FJ; Bann M; Verbeeck C; Price RW; Smithson L; Sonoda L; Wagg K; Rangachari V; Zou F; Younkin SG; Graff-Radford N; Dickson D; Rosenberry T; Golde TE
    J Neurosci; 2008 Jun; 28(23):6030-6. PubMed ID: 18524908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
    Tian J; Shi J; Zhang L; Yin J; Hu Q; Xu Y; Sheng S; Wang P; Ren Y; Wang R; Wang Y
    Curr Alzheimer Res; 2009 Apr; 6(2):118-31. PubMed ID: 19355846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia.
    Tamayev R; Matsuda S; Arancio O; D'Adamio L
    EMBO Mol Med; 2012 Mar; 4(3):171-9. PubMed ID: 22170863
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E; Torrance M; Mante M; Adame A; Paulino A; Rose JB; Crews L; Moessler H; Masliah E
    J Neurosci Res; 2006 May; 83(7):1252-61. PubMed ID: 16511867
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
    Farris W; Mansourian S; Chang Y; Lindsley L; Eckman EA; Frosch MP; Eckman CB; Tanzi RE; Selkoe DJ; Guenette S
    Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4162-7. PubMed ID: 12634421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission.
    Yin T; Yao W; Norris KA; D'Adamio L
    J Biol Chem; 2021 Sep; 297(3):101089. PubMed ID: 34416235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer's disease.
    Lauer AA; Mett J; Janitschke D; Thiel A; Stahlmann CP; Bachmann CM; Ritzmann F; Schrul B; Müller UC; Stein R; Riemenschneider M; Grimm HS; Hartmann T; Grimm MOW
    Aging Cell; 2020 Nov; 19(11):e13264. PubMed ID: 33128835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production.
    Fotinopoulou A; Tsachaki M; Vlavaki M; Poulopoulos A; Rostagno A; Frangione B; Ghiso J; Efthimiopoulos S
    J Biol Chem; 2005 Sep; 280(35):30768-72. PubMed ID: 16027166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.
    Matsuda S; Matsuda Y; D'Adamio L
    J Biol Chem; 2009 Jun; 284(23):15815-25. PubMed ID: 19366692
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme.
    Vekrellis K; Ye Z; Qiu WQ; Walsh D; Hartley D; Chesneau V; Rosner MR; Selkoe DJ
    J Neurosci; 2000 Mar; 20(5):1657-65. PubMed ID: 10684867
    [TBL] [Abstract][Full Text] [Related]  

  • 15. APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant.
    Tamayev R; Matsuda S; Giliberto L; Arancio O; D'Adamio L
    EMBO J; 2011 May; 30(12):2501-9. PubMed ID: 21587206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate.
    Matsuda S; Giliberto L; Matsuda Y; McGowan EM; D'Adamio L
    J Neurosci; 2008 Aug; 28(35):8668-76. PubMed ID: 18753367
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1-23) and amyloid beta-peptide (Abeta1-40): Implications for Bri2 effects on processing of amyloid precursor protein and Abeta aggregation.
    Peng S; Fitzen M; Jörnvall H; Johansson J
    Biochem Biophys Res Commun; 2010 Mar; 393(3):356-61. PubMed ID: 20036644
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation.
    Yasukawa T; Tsutsui A; Tomomori-Sato C; Sato S; Saraf A; Washburn MP; Florens L; Terada T; Shimizu K; Conaway RC; Conaway JW; Aso T
    Cell Rep; 2020 Mar; 30(10):3478-3491.e6. PubMed ID: 32160551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production.
    Matsuda S; Giliberto L; Matsuda Y; Davies P; McGowan E; Pickford F; Ghiso J; Frangione B; D'Adamio L
    J Biol Chem; 2005 Aug; 280(32):28912-6. PubMed ID: 15983050
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.
    Qiu WQ; Walsh DM; Ye Z; Vekrellis K; Zhang J; Podlisny MB; Rosner MR; Safavi A; Hersh LB; Selkoe DJ
    J Biol Chem; 1998 Dec; 273(49):32730-8. PubMed ID: 9830016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.