BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

486 related articles for article (PubMed ID: 21875949)

  • 1. Ginseng (Panax quinquefolius) attenuates leptin-induced cardiac hypertrophy through inhibition of p115Rho guanine nucleotide exchange factor-RhoA/Rho-associated, coiled-coil containing protein kinase-dependent mitogen-activated protein kinase pathway activation.
    Moey M; Rajapurohitam V; Zeidan A; Karmazyn M
    J Pharmacol Exp Ther; 2011 Dec; 339(3):746-56. PubMed ID: 21875949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Leptin-induced cardiomyocyte hypertrophy reveals both calcium-dependent and calcium-independent/RhoA-dependent calcineurin activation and NFAT nuclear translocation.
    Rajapurohitam V; Izaddoustdar F; Martinez-Abundis E; Karmazyn M
    Cell Signal; 2012 Dec; 24(12):2283-90. PubMed ID: 22917533
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Leptin-induced cardiomyocyte hypertrophy involves selective caveolae and RhoA/ROCK-dependent p38 MAPK translocation to nuclei.
    Zeidan A; Javadov S; Chakrabarti S; Karmazyn M
    Cardiovasc Res; 2008 Jan; 77(1):64-72. PubMed ID: 18006472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway.
    Hunter JC; Zeidan A; Javadov S; Kilić A; Rajapurohitam V; Karmazyn M
    J Mol Cell Cardiol; 2009 Dec; 47(6):810-8. PubMed ID: 19799911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Actin cytoskeleton dynamics promotes leptin-induced vascular smooth muscle hypertrophy via RhoA/ROCK- and phosphatidylinositol 3-kinase/protein kinase B-dependent pathways.
    Zeidan A; Paylor B; Steinhoff KJ; Javadov S; Rajapurohitam V; Chakrabarti S; Karmazyn M
    J Pharmacol Exp Ther; 2007 Sep; 322(3):1110-6. PubMed ID: 17562852
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes.
    Zeidan A; Javadov S; Karmazyn M
    Cardiovasc Res; 2006 Oct; 72(1):101-11. PubMed ID: 16901475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes.
    Pan J; Singh US; Takahashi T; Oka Y; Palm-Leis A; Herbelin BS; Baker KM
    J Cell Physiol; 2005 Feb; 202(2):536-53. PubMed ID: 15316932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Knockdown of farnesylpyrophosphate synthase prevents angiotensin II-mediated cardiac hypertrophy.
    Ye Y; Mou Y; Bai B; Li L; Chen GP; Hu SJ
    Int J Biochem Cell Biol; 2010 Dec; 42(12):2056-64. PubMed ID: 20884373
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prevention of RhoA activation and cofilin-mediated actin polymerization mediates the antihypertrophic effect of adenosine receptor agonists in angiotensin II- and endothelin-1-treated cardiomyocytes.
    Zeidan A; Gan XT; Thomas A; Karmazyn M
    Mol Cell Biochem; 2014 Jan; 385(1-2):239-48. PubMed ID: 24096734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation.
    Guo J; Gan XT; Haist JV; Rajapurohitam V; Zeidan A; Faruq NS; Karmazyn M
    Circ Heart Fail; 2011 Jan; 4(1):79-88. PubMed ID: 20971938
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Angiotensin II up-regulates the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF), a regulator of G protein signaling domain-containing RhoGEF, in vascular smooth muscle cells.
    Ying Z; Jin L; Palmer T; Webb RC
    Mol Pharmacol; 2006 Mar; 69(3):932-40. PubMed ID: 16354763
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1.
    Rajapurohitam V; Javadov S; Purdham DM; Kirshenbaum LA; Karmazyn M
    J Mol Cell Cardiol; 2006 Aug; 41(2):265-74. PubMed ID: 16806260
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: role of sphingosine-1-phosphate.
    Frias MA; James RW; Gerber-Wicht C; Lang U
    Cardiovasc Res; 2009 May; 82(2):313-23. PubMed ID: 19151362
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ginseng reverses established cardiomyocyte hypertrophy and postmyocardial infarction-induced hypertrophy and heart failure.
    Moey M; Gan XT; Huang CX; Rajapurohitam V; Martínez-Abundis E; Lui EM; Karmazyn M
    Circ Heart Fail; 2012 Jul; 5(4):504-14. PubMed ID: 22576957
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p38 mitogen-activated protein kinase (MAPK) is activated by noradrenaline and serves a cardioprotective role, whereas adrenaline induces p38 MAPK dephosphorylation.
    Tsang MY; Rabkin SW
    Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):e12-9. PubMed ID: 19413597
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK.
    Chorianopoulos E; Heger T; Lutz M; Frank D; Bea F; Katus HA; Frey N
    Basic Res Cardiol; 2010 Mar; 105(2):301-13. PubMed ID: 19629561
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of inducible nitric oxide synthase in induction of RhoA expression in hearts from diabetic rats.
    Soliman H; Craig GP; Nagareddy P; Yuen VG; Lin G; Kumar U; McNeill JH; Macleod KM
    Cardiovasc Res; 2008 Jul; 79(2):322-30. PubMed ID: 18411229
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene.
    Nakaoka Y; Shioyama W; Kunimoto S; Arita Y; Higuchi K; Yamamoto K; Fujio Y; Nishida K; Kuroda T; Hirota H; Yamauchi-Takihara K; Hirano T; Komuro I; Mochizuki N
    J Mol Cell Cardiol; 2010 Aug; 49(2):157-64. PubMed ID: 20226789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery.
    Teixeira CE; Jin L; Ying Z; Palmer T; Priviero FB; Webb RC
    Clin Exp Pharmacol Physiol; 2005 Oct; 32(10):817-24. PubMed ID: 16173942
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1.
    Fan GC; Yuan Q; Song G; Wang Y; Chen G; Qian J; Zhou X; Lee YJ; Ashraf M; Kranias EG
    Circ Res; 2006 Nov; 99(11):1233-42. PubMed ID: 17068291
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.