BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 21877721)

  • 1. Modeling the chemical step utilized by human alkyladenine DNA glycosylase: a concerted mechanism AIDS in selectively excising damaged purines.
    Rutledge LR; Wetmore SD
    J Am Chem Soc; 2011 Oct; 133(40):16258-69. PubMed ID: 21877721
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines.
    O'Brien PJ; Ellenberger T
    Biochemistry; 2003 Oct; 42(42):12418-29. PubMed ID: 14567703
    [TBL] [Abstract][Full Text] [Related]  

  • 3. QM/MM Study of the Reaction Catalyzed by Alkyladenine DNA Glycosylase: Examination of the Substrate Specificity of a DNA Repair Enzyme.
    Lenz SAP; Wetmore SD
    J Phys Chem B; 2017 Dec; 121(49):11096-11108. PubMed ID: 29148771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluating the Substrate Selectivity of Alkyladenine DNA Glycosylase: The Synergistic Interplay of Active Site Flexibility and Water Reorganization.
    Lenz SA; Wetmore SD
    Biochemistry; 2016 Feb; 55(5):798-808. PubMed ID: 26765542
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by AlkA.
    Taylor EL; O'Brien PJ
    Biochemistry; 2015 Jan; 54(3):898-908. PubMed ID: 25537480
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by human alkyladenine DNA glycosylase.
    Wolfe AE; O'Brien PJ
    Biochemistry; 2009 Dec; 48(48):11357-69. PubMed ID: 19883114
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The formation of catalytically competent enzyme-substrate complex is not a bottleneck in lesion excision by human alkyladenine DNA glycosylase.
    Kuznetsov NA; Kiryutin AS; Kuznetsova AA; Panov MS; Barsukova MO; Yurkovskaya AV; Fedorova OS
    J Biomol Struct Dyn; 2017 Apr; 35(5):950-967. PubMed ID: 27025273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrolysis of the damaged deoxythymidine glycol nucleoside and comparison to canonical DNA.
    Navarro-Whyte L; Kellie JL; Lenz SA; Wetmore SD
    Phys Chem Chem Phys; 2013 Nov; 15(44):19343-52. PubMed ID: 24121561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).
    Lee CY; Delaney JC; Kartalou M; Lingaraju GM; Maor-Shoshani A; Essigmann JM; Samson LD
    Biochemistry; 2009 Mar; 48(9):1850-61. PubMed ID: 19219989
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Promiscuous DNA alkyladenine glycosylase dramatically favors a bound lesion over undamaged adenine.
    Alexandrova AN
    Biophys Chem; 2010 Nov; 152(1-3):118-27. PubMed ID: 20840885
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Slow base excision by human alkyladenine DNA glycosylase limits the rate of formation of AP sites and AP endonuclease 1 does not stimulate base excision.
    Maher RL; Vallur AC; Feller JA; Bloom LB
    DNA Repair (Amst); 2007 Jan; 6(1):71-81. PubMed ID: 17018265
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alkylpurine-DNA-N-glycosylase excision of 7-(hydroxymethyl)-1,N6-ethenoadenine, a glycidaldehyde-derived DNA adduct.
    Wang P; Guliaev AB; Elder RH; Hang B
    DNA Repair (Amst); 2006 Jan; 5(1):23-31. PubMed ID: 16290249
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase.
    Hendershot JM; Wolfe AE; O'Brien PJ
    Biochemistry; 2011 Mar; 50(11):1864-74. PubMed ID: 21244040
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-glycosyl bond formation catalyzed by human alkyladenine DNA glycosylase.
    Admiraal SJ; O'Brien PJ
    Biochemistry; 2010 Oct; 49(42):9024-6. PubMed ID: 20873830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The efficiency of hypoxanthine excision by alkyladenine DNA glycosylase is altered by changes in nearest neighbor bases.
    Vallur AC; Maher RL; Bloom LB
    DNA Repair (Amst); 2005 Sep; 4(10):1088-98. PubMed ID: 15990363
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.
    Engelward BP; Weeda G; Wyatt MD; Broekhof JL; de Wit J; Donker I; Allan JM; Gold B; Hoeijmakers JH; Samson LD
    Proc Natl Acad Sci U S A; 1997 Nov; 94(24):13087-92. PubMed ID: 9371804
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigation of the Flipping Dynamics of 1, N6-Ethenoadenine in Alkyladenine DNA Glycosylase.
    Liu B; Qi Y; Wang X; Gao X; Yao Y; Zhang L
    J Phys Chem B; 2024 Feb; 128(7):1606-1617. PubMed ID: 38331753
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Global Repair Profile of Human Alkyladenine DNA Glycosylase on Nucleosomes Reveals DNA Packaging Effects.
    Kennedy EE; Li C; Delaney S
    ACS Chem Biol; 2019 Aug; 14(8):1687-1692. PubMed ID: 31310499
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantum theoretical study of cleavage of the glycosidic bond of 2'-deoxyadenosine: base excision-repair mechanism of DNA by MutY.
    Tiwari S; Agnihotri N; Mishra PC
    J Phys Chem B; 2011 Mar; 115(12):3200-7. PubMed ID: 21384840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A QM/QM investigation of the hUNG2 reaction surface: the untold tale of a catalytic residue.
    Przybylski JL; Wetmore SD
    Biochemistry; 2011 May; 50(19):4218-27. PubMed ID: 21473605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.