BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

564 related articles for article (PubMed ID: 21878679)

  • 1. AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer.
    Chan JC; Hannan KM; Riddell K; Ng PY; Peck A; Lee RS; Hung S; Astle MV; Bywater M; Wall M; Poortinga G; Jastrzebski K; Sheppard KE; Hemmings BA; Hall MN; Johnstone RW; McArthur GA; Hannan RD; Pearson RB
    Sci Signal; 2011 Aug; 4(188):ra56. PubMed ID: 21878679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo.
    Devlin JR; Hannan KM; Ng PY; Bywater MJ; Shortt J; Cullinane C; McArthur GA; Johnstone RW; Hannan RD; Pearson RB
    FEBS J; 2013 Nov; 280(21):5307-16. PubMed ID: 23331925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTORC1 signaling controls multiple steps in ribosome biogenesis.
    Iadevaia V; Liu R; Proud CG
    Semin Cell Dev Biol; 2014 Dec; 36():113-20. PubMed ID: 25148809
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster.
    Piazzi M; Bavelloni A; Gallo A; Faenza I; Blalock WL
    Int J Mol Sci; 2019 Jun; 20(11):. PubMed ID: 31163577
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ccr4-not regulates RNA polymerase I transcription and couples nutrient signaling to the control of ribosomal RNA biogenesis.
    Laribee RN; Hosni-Ahmed A; Workman JJ; Chen H
    PLoS Genet; 2015 Mar; 11(3):e1005113. PubMed ID: 25815716
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signaling to the ribosome in cancer--It is more than just mTORC1.
    Hannan KM; Sanij E; Hein N; Hannan RD; Pearson RB
    IUBMB Life; 2011 Feb; 63(2):79-85. PubMed ID: 21360636
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma.
    Devlin JR; Hannan KM; Hein N; Cullinane C; Kusnadi E; Ng PY; George AJ; Shortt J; Bywater MJ; Poortinga G; Sanij E; Kang J; Drygin D; O'Brien S; Johnstone RW; McArthur GA; Hannan RD; Pearson RB
    Cancer Discov; 2016 Jan; 6(1):59-70. PubMed ID: 26490423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription.
    Kang J; Kusnadi EP; Ogden AJ; Hicks RJ; Bammert L; Kutay U; Hung S; Sanij E; Hannan RD; Hannan KM; Pearson RB
    Oncotarget; 2016 Aug; 7(31):48887-48904. PubMed ID: 27385002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A role for c-Myc in the regulation of ribosomal RNA processing.
    Schlosser I; Hölzel M; Mürnseer M; Burtscher H; Weidle UH; Eick D
    Nucleic Acids Res; 2003 Nov; 31(21):6148-56. PubMed ID: 14576301
    [TBL] [Abstract][Full Text] [Related]  

  • 10. c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle.
    Mori T; Ato S; Knudsen JR; Henriquez-Olguin C; Li Z; Wakabayashi K; Suginohara T; Higashida K; Tamura Y; Nakazato K; Jensen TE; Ogasawara R
    Am J Physiol Endocrinol Metab; 2021 Oct; 321(4):E551-E559. PubMed ID: 34423683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of rDNA transcription in response to growth factors, nutrients and energy.
    Kusnadi EP; Hannan KM; Hicks RJ; Hannan RD; Pearson RB; Kang J
    Gene; 2015 Feb; 556(1):27-34. PubMed ID: 25447905
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of mTORC2 by association with the ribosome.
    Zinzalla V; Stracka D; Oppliger W; Hall MN
    Cell; 2011 Mar; 144(5):757-68. PubMed ID: 21376236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I.
    Grandori C; Gomez-Roman N; Felton-Edkins ZA; Ngouenet C; Galloway DA; Eisenman RN; White RJ
    Nat Cell Biol; 2005 Mar; 7(3):311-8. PubMed ID: 15723054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CMTM6 attenuates cisplatin-induced cell death in OSCC by regulating AKT/c-Myc-driven ribosome biogenesis.
    Mohapatra P; Mohanty S; Ansari SA; Shriwas O; Ghosh A; Rath R; Majumdar SKD; Swain RK; Raghav SK; Dash R
    FASEB J; 2022 Oct; 36(10):e22566. PubMed ID: 36165231
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription.
    Li Z; Hann SR
    Oncogene; 2013 Apr; 32(15):1988-94. PubMed ID: 22665062
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
    Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.
    Grewal SS; Li L; Orian A; Eisenman RN; Edgar BA
    Nat Cell Biol; 2005 Mar; 7(3):295-302. PubMed ID: 15723055
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer.
    Rebello RJ; Kusnadi E; Cameron DP; Pearson HB; Lesmana A; Devlin JR; Drygin D; Clark AK; Porter L; Pedersen J; Sandhu S; Risbridger GP; Pearson RB; Hannan RD; Furic L
    Clin Cancer Res; 2016 Nov; 22(22):5539-5552. PubMed ID: 27486174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway.
    Grewal SS; Evans JR; Edgar BA
    J Cell Biol; 2007 Dec; 179(6):1105-13. PubMed ID: 18086911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy.
    Woods SJ; Hannan KM; Pearson RB; Hannan RD
    Biochim Biophys Acta; 2015 Jul; 1849(7):821-9. PubMed ID: 25464032
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.