These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
138 related articles for article (PubMed ID: 21885288)
1. Design and synthesis of new prostaglandin D₂ receptor antagonists. Iwahashi M; Takahashi E; Tanaka M; Matsunaga Y; Okada Y; Matsumoto R; Nambu F; Nakai H; Toda M Bioorg Med Chem; 2011 Sep; 19(18):5361-71. PubMed ID: 21885288 [TBL] [Abstract][Full Text] [Related]
2. Discovery of new orally active prostaglandin D2 receptor antagonists. Iwahashi M; Naganawa A; Kinoshita A; Shimabukuro A; Nishiyama T; Ogawa S; Matsunaga Y; Tsukamoto K; Okada Y; Matsumoto R; Nambu F; Oumi R; Odagaki Y; Katagi J; Yano K; Tani K; Nakai H; Toda M Bioorg Med Chem; 2011 Nov; 19(22):6935-48. PubMed ID: 21982795 [TBL] [Abstract][Full Text] [Related]
3. Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists. Liu JJ; Wang Y; Johnson MG; Li AR; Shen W; Wang X; Su Y; Brown M; Van Lengerich B; Rickel E; Martin T; Budelsky A; Seitz L; Danao J; Tang HL; Collins T; Medina JC Bioorg Med Chem Lett; 2012 Feb; 22(4):1686-9. PubMed ID: 22264478 [TBL] [Abstract][Full Text] [Related]
4. Discovery of new chemical leads for prostaglandin D2 receptor antagonists. Torisu K; Kobayashi K; Iwahashi M; Egashira H; Nakai Y; Okada Y; Nanbu F; Ohuchida S; Nakai H; Toda M Bioorg Med Chem Lett; 2004 Sep; 14(17):4557-62. PubMed ID: 15357992 [TBL] [Abstract][Full Text] [Related]
5. Development of prostaglandin D2 receptor antagonist: discovery of highly potent antagonists. Torisu K; Kobayashi K; Iwahashi M; Nakai Y; Onoda T; Nagase T; Sugimoto I; Okada Y; Matsumoto R; Nanbu F; Ohuchida S; Nakai H; Masaaki Toda Bioorg Med Chem; 2004 Sep; 12(17):4685-700. PubMed ID: 15358295 [TBL] [Abstract][Full Text] [Related]
6. Discovery of selective indole-based prostaglandin D₂ receptor antagonist. Iwahashi M; Shimabukuro A; Onoda T; Matsunaga Y; Okada Y; Matsumoto R; Nambu F; Nakai H; Toda M Bioorg Med Chem; 2011 Aug; 19(15):4574-88. PubMed ID: 21737285 [TBL] [Abstract][Full Text] [Related]
7. Discovery of orally active prostaglandin D2 receptor antagonists. Torisu K; Kobayashi K; Iwahashi M; Nakai Y; Onoda T; Nagase T; Sugimoto I; Okada Y; Matsumoto R; Nanbu F; Ohuchida S; Nakai H; Toda M Bioorg Med Chem Lett; 2004 Oct; 14(19):4891-5. PubMed ID: 15341946 [TBL] [Abstract][Full Text] [Related]
8. Discovery and optimization of a biphenylacetic acid series of prostaglandin D2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis. Scott JM; Baccei C; Bain G; Broadhead A; Evans JF; Fagan P; Hutchinson JH; King C; Lorrain DS; Lee C; Prasit P; Prodanovich P; Santini A; Stearns BA Bioorg Med Chem Lett; 2011 Nov; 21(21):6608-12. PubMed ID: 21958540 [TBL] [Abstract][Full Text] [Related]
9. Development of a prostaglandin D2 receptor antagonist: discovery of a new chemical lead. Torisu K; Kobayashi K; Iwahashi M; Egashira H; Nakai Y; Okada Y; Nanbu F; Ohuchida S; Nakai H; Toda M Eur J Med Chem; 2005 May; 40(5):505-19. PubMed ID: 15893024 [TBL] [Abstract][Full Text] [Related]
10. A novel DP2 receptor antagonist (AM-461): a patent evaluation of WO2011085033. Norman P Expert Opin Ther Pat; 2011 Dec; 21(12):1931-6. PubMed ID: 22082220 [TBL] [Abstract][Full Text] [Related]
11. Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists. Katsura Y; Zhang X; Homma K; Rice KC; Calderon SN; Rothman RB; Yamamura HI; Davis P; Flippen-Anderson JL; Xu H; Becketts K; Foltz EJ; Porreca F J Med Chem; 1997 Aug; 40(18):2936-47. PubMed ID: 9288176 [TBL] [Abstract][Full Text] [Related]
12. Solving time-dependent CYP3A4 inhibition for a series of indole-phenylacetic acid dual antagonists of the PGD(2) receptors CRTH2 and DP. Johnson MG; Liu JJ; Li AR; van Lengerich B; Wang S; Medina JC; Collins TL; Danao J; Seitz L; Willee A; D'Souza W; Budelsky AL; Fan PW; Wong SG Bioorg Med Chem Lett; 2014 Jul; 24(13):2877-80. PubMed ID: 24825301 [TBL] [Abstract][Full Text] [Related]
13. Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism. Wang Y; Fu Z; Schmitt M; Wang X; Shen W; Rickel E; Martin T; Budelsky A; Marshall D; Collins T; Tang HL; Medina JC; Liu JJ Bioorg Med Chem Lett; 2012 Jan; 22(1):367-70. PubMed ID: 22119474 [TBL] [Abstract][Full Text] [Related]
14. Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2. Armer RE; Ashton MR; Boyd EA; Brennan CJ; Brookfield FA; Gazi L; Gyles SL; Hay PA; Hunter MG; Middlemiss D; Whittaker M; Xue L; Pettipher R J Med Chem; 2005 Oct; 48(20):6174-7. PubMed ID: 16190744 [TBL] [Abstract][Full Text] [Related]
15. Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists. Torisu K; Kobayashi K; Iwahashi M; Nakai Y; Onoda T; Nagase T; Sugimoto I; Okada Y; Matsumoto R; Nanbu F; Ohuchida S; Nakai H; Toda M Bioorg Med Chem; 2004 Oct; 12(20):5361-78. PubMed ID: 15388164 [TBL] [Abstract][Full Text] [Related]
16. Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR. Nishikawa-Shimono R; Sekiguchi Y; Koami T; Kawamura M; Wakasugi D; Watanabe K; Wakahara S; Kimura K; Yamanobe S; Takayama T Bioorg Med Chem; 2013 Dec; 21(24):7674-85. PubMed ID: 24216094 [TBL] [Abstract][Full Text] [Related]
17. Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases. Crosignani S; Page P; Missotten M; Colovray V; Cleva C; Arrighi JF; Atherall J; Macritchie J; Martin T; Humbert Y; Gaudet M; Pupowicz D; Maio M; Pittet PA; Golzio L; Giachetti C; Rocha C; Bernardinelli G; Filinchuk Y; Scheer A; Schwarz MK; Chollet A J Med Chem; 2008 Apr; 51(7):2227-43. PubMed ID: 18318469 [TBL] [Abstract][Full Text] [Related]
18. Discovery of novel and potent CRTH2 antagonists. Ito S; Terasaka T; Zenkoh T; Matsuda H; Hayashida H; Nagata H; Imamura Y; Kobayashi M; Takeuchi M; Ohta M Bioorg Med Chem Lett; 2012 Jan; 22(2):1194-7. PubMed ID: 22178554 [TBL] [Abstract][Full Text] [Related]
19. 6,7-Dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidines and their derivatives as novel corticotropin-releasing factor 1 receptor antagonists. Saito T; Obitsu T; Kondo T; Matsui T; Nagao Y; Kusumi K; Matsumura N; Ueno S; Kishi A; Katsumata S; Kagamiishi Y; Nakai H; Toda M Bioorg Med Chem; 2011 Sep; 19(18):5432-45. PubMed ID: 21865047 [TBL] [Abstract][Full Text] [Related]
20. Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation. Bain G; Lorrain DS; Stebbins KJ; Broadhead AR; Santini AM; Prodanovich P; Darlington J; King CD; Lee C; Baccei C; Stearns B; Troung Y; Hutchinson JH; Prasit P; Evans JF J Pharmacol Exp Ther; 2011 Jul; 338(1):290-301. PubMed ID: 21487069 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]