198 related articles for article (PubMed ID: 21885877)
1. Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.
Li S; Kanno S; Watanabe R; Ogiwara H; Kohno T; Watanabe G; Yasui A; Lieber MR
J Biol Chem; 2011 Oct; 286(42):36368-77. PubMed ID: 21885877
[TBL] [Abstract][Full Text] [Related]
2. Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF).
Shirodkar P; Fenton AL; Meng L; Koch CA
J Biol Chem; 2013 Jul; 288(27):19604-13. PubMed ID: 23689425
[TBL] [Abstract][Full Text] [Related]
3. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
[TBL] [Abstract][Full Text] [Related]
4. APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation.
Macrae CJ; McCulloch RD; Ylanko J; Durocher D; Koch CA
DNA Repair (Amst); 2008 Feb; 7(2):292-302. PubMed ID: 18077224
[TBL] [Abstract][Full Text] [Related]
5. APLF promotes the assembly and activity of non-homologous end joining protein complexes.
Grundy GJ; Rulten SL; Zeng Z; Arribas-Bosacoma R; Iles N; Manley K; Oliver A; Caldecott KW
EMBO J; 2013 Jan; 32(1):112-25. PubMed ID: 23178593
[TBL] [Abstract][Full Text] [Related]
6. A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.
Kanno S; Kuzuoka H; Sasao S; Hong Z; Lan L; Nakajima S; Yasui A
EMBO J; 2007 Apr; 26(8):2094-103. PubMed ID: 17396150
[TBL] [Abstract][Full Text] [Related]
7. APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks.
Iles N; Rulten S; El-Khamisy SF; Caldecott KW
Mol Cell Biol; 2007 May; 27(10):3793-803. PubMed ID: 17353262
[TBL] [Abstract][Full Text] [Related]
8. Effects of DNA end configuration on XRCC4-DNA ligase IV and its stimulation of Artemis activity.
Gerodimos CA; Chang HHY; Watanabe G; Lieber MR
J Biol Chem; 2017 Aug; 292(34):13914-13924. PubMed ID: 28696258
[TBL] [Abstract][Full Text] [Related]
9. Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.
Chang HHY; Watanabe G; Gerodimos CA; Ochi T; Blundell TL; Jackson SP; Lieber MR
J Biol Chem; 2016 Nov; 291(47):24377-24389. PubMed ID: 27703001
[TBL] [Abstract][Full Text] [Related]
10. Biochemical evidence for Ku-independent backup pathways of NHEJ.
Wang H; Perrault AR; Takeda Y; Qin W; Wang H; Iliakis G
Nucleic Acids Res; 2003 Sep; 31(18):5377-88. PubMed ID: 12954774
[TBL] [Abstract][Full Text] [Related]
11. Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains.
Cherry AL; Nott TJ; Kelly G; Rulten SL; Caldecott KW; Smerdon SJ
DNA Repair (Amst); 2015 Nov; 35():116-25. PubMed ID: 26519825
[TBL] [Abstract][Full Text] [Related]
12. Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.
Richter C; Marquardt S; Li F; Spitschak A; Murr N; Edelhäuser BAH; Iliakis G; Pützer BM; Logotheti S
J Exp Clin Cancer Res; 2019 Jul; 38(1):292. PubMed ID: 31287003
[TBL] [Abstract][Full Text] [Related]
13. C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin.
Liu S; Liu X; Kamdar RP; Wanotayan R; Sharma MK; Adachi N; Matsumoto Y
Biochem Biophys Res Commun; 2013 Sep; 439(2):173-8. PubMed ID: 23994631
[TBL] [Abstract][Full Text] [Related]
14. XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nemoz C; Ropars V; Frit P; Gontier A; Drevet P; Yu J; Guerois R; Pitois A; Comte A; Delteil C; Barboule N; Legrand P; Baconnais S; Yin Y; Tadi S; Barbet-Massin E; Berger I; Le Cam E; Modesti M; Rothenberg E; Calsou P; Charbonnier JB
Nat Struct Mol Biol; 2018 Oct; 25(10):971-980. PubMed ID: 30291363
[TBL] [Abstract][Full Text] [Related]
15. Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence.
Gu J; Lu H; Tsai AG; Schwarz K; Lieber MR
Nucleic Acids Res; 2007; 35(17):5755-62. PubMed ID: 17717001
[TBL] [Abstract][Full Text] [Related]
16. Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
Calsou P; Delteil C; Frit P; Drouet J; Salles B
J Mol Biol; 2003 Feb; 326(1):93-103. PubMed ID: 12547193
[TBL] [Abstract][Full Text] [Related]
17. Rejoining of DNA double-strand breaks in vitro by single-strand annealing.
Göttlich B; Reichenberger S; Feldmann E; Pfeiffer P
Eur J Biochem; 1998 Dec; 258(2):387-95. PubMed ID: 9874203
[TBL] [Abstract][Full Text] [Related]
18. PARP-3 and APLF function together to accelerate nonhomologous end-joining.
Rulten SL; Fisher AE; Robert I; Zuma MC; Rouleau M; Ju L; Poirier G; Reina-San-Martin B; Caldecott KW
Mol Cell; 2011 Jan; 41(1):33-45. PubMed ID: 21211721
[TBL] [Abstract][Full Text] [Related]
19. Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.
Strande N; Roberts SA; Oh S; Hendrickson EA; Ramsden DA
J Biol Chem; 2012 Apr; 287(17):13686-93. PubMed ID: 22362780
[TBL] [Abstract][Full Text] [Related]
20. Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.
Roberts SA; Strande N; Burkhalter MD; Strom C; Havener JM; Hasty P; Ramsden DA
Nature; 2010 Apr; 464(7292):1214-7. PubMed ID: 20383123
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]