BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 21887268)

  • 1. Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.
    MacDonald BT; Semenov MV; Huang H; He X
    PLoS One; 2011; 6(8):e23537. PubMed ID: 21887268
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.
    Wu G; Huang H; Garcia Abreu J; He X
    PLoS One; 2009; 4(3):e4926. PubMed ID: 19293931
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6.
    MacDonald BT; Yokota C; Tamai K; Zeng X; He X
    J Biol Chem; 2008 Jun; 283(23):16115-23. PubMed ID: 18362152
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction.
    Wang S; Yin J; Chen D; Nie F; Song X; Fei C; Miao H; Jing C; Ma W; Wang L; Xie S; Li C; Zeng R; Pan W; Hao X; Li L
    Nat Chem Biol; 2013 Sep; 9(9):579-85. PubMed ID: 23892894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.
    Goel S; Chin EN; Fakhraldeen SA; Berry SM; Beebe DJ; Alexander CM
    J Biol Chem; 2012 May; 287(20):16454-66. PubMed ID: 22433869
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells.
    Peröbner I; Karow M; Jochum M; Neth P
    Int J Biochem Cell Biol; 2012 Nov; 44(11):1970-82. PubMed ID: 22871567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation.
    Chen J; Yan H; Ren DN; Yin Y; Li Z; He Q; Wo D; Ho MS; Chen Y; Liu Z; Yang J; Liu S; Zhu W
    Cell Signal; 2014 May; 26(5):1068-74. PubMed ID: 24412751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.
    Zeng X; Huang H; Tamai K; Zhang X; Harada Y; Yokota C; Almeida K; Wang J; Doble B; Woodgett J; Wynshaw-Boris A; Hsieh JC; He X
    Development; 2008 Jan; 135(2):367-75. PubMed ID: 18077588
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling.
    Piao S; Lee SH; Kim H; Yum S; Stamos JL; Xu Y; Lee SJ; Lee J; Oh S; Han JK; Park BJ; Weis WI; Ha NC
    PLoS One; 2008; 3(12):e4046. PubMed ID: 19107203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling.
    Fei C; Li Z; Li C; Chen Y; Chen Z; He X; Mao L; Wang X; Zeng R; Li L
    Mol Cell Biol; 2013 Oct; 33(20):4095-105. PubMed ID: 23959799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.
    Lin C; Lu W; Zhang W; Londoño-Joshi AI; Buchsbaum DJ; Bu G; Li Y
    PLoS One; 2013; 8(2):e58102. PubMed ID: 23469146
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies.
    Kim SE; Huang H; Zhao M; Zhang X; Zhang A; Semonov MV; MacDonald BT; Zhang X; Garcia Abreu J; Peng L; He X
    Science; 2013 May; 340(6134):867-70. PubMed ID: 23579495
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
    Nagaoka T; Karasawa H; Turbyville T; Rangel MC; Castro NP; Gonzales M; Baker A; Seno M; Lockett S; Greer YE; Rubin JS; Salomon DS; Bianco C
    Cell Signal; 2013 Jan; 25(1):178-89. PubMed ID: 23022962
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.
    Haÿ E; Buczkowski T; Marty C; Da Nascimento S; Sonnet P; Marie PJ
    J Bone Miner Res; 2012 Sep; 27(9):1852-63. PubMed ID: 22576936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5).
    Palsgaard J; Emanuelli B; Winnay JN; Sumara G; Karsenty G; Kahn CR
    J Biol Chem; 2012 Apr; 287(15):12016-26. PubMed ID: 22337886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.
    Cselenyi CS; Jernigan KK; Tahinci E; Thorne CA; Lee LA; Lee E
    Proc Natl Acad Sci U S A; 2008 Jun; 105(23):8032-7. PubMed ID: 18509060
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina.
    Singh HD; Ma JX; Takahashi Y
    Biochem Biophys Res Commun; 2021 Mar; 545():8-13. PubMed ID: 33545636
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
    Sebastian A; Hum NR; Murugesh DK; Hatsell S; Economides AN; Loots GG
    PLoS One; 2017; 12(11):e0188264. PubMed ID: 29176883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.
    Hay E; Faucheu C; Suc-Royer I; Touitou R; Stiot V; Vayssière B; Baron R; Roman-Roman S; Rawadi G
    J Biol Chem; 2005 Apr; 280(14):13616-23. PubMed ID: 15699046
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.
    Ahn VE; Chu ML; Choi HJ; Tran D; Abo A; Weis WI
    Dev Cell; 2011 Nov; 21(5):862-73. PubMed ID: 22000856
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.