These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 21887331)

  • 1. Overexpression of the HIF hydroxylases PHD1, PHD2, PHD3 and FIH are individually and collectively unfavorable prognosticators for NSCLC survival.
    Andersen S; Donnem T; Stenvold H; Al-Saad S; Al-Shibli K; Busund LT; Bremnes RM
    PLoS One; 2011; 6(8):e23847. PubMed ID: 21887331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.
    Rawluszko AA; Bujnicka KE; Horbacka K; Krokowicz P; Jagodziński PP
    BMC Cancer; 2013 Nov; 13():526. PubMed ID: 24195777
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA methylation analysis of the HIF-1α prolyl hydroxylase domain genes PHD1, PHD2, PHD3 and the factor inhibiting HIF gene FIH in invasive breast carcinomas.
    Huang KT; Mikeska T; Dobrovic A; Fox SB
    Histopathology; 2010 Sep; 57(3):451-60. PubMed ID: 20727020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression.
    Yan M; Rayoo M; Takano EA; ; Fox SB
    Br J Cancer; 2009 Oct; 101(7):1168-74. PubMed ID: 19724277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma.
    Ma M; Hua S; Li G; Wang S; Cheng X; He S; Wu P; Chen X
    Oncotarget; 2017 Feb; 8(8):12983-13002. PubMed ID: 28099905
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen.
    Fox SB; Generali D; Berruti A; Brizzi MP; Campo L; Bonardi S; Bersiga A; Allevi G; Milani M; Aguggini S; Mele T; Dogliotti L; Bottini A; Harris AL
    Breast Cancer Res; 2011 Feb; 13(1):R16. PubMed ID: 21291529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [The expression of hypoxia-inducible factor-1alpha and its hydroxylases in pulmonary arteries of patient with chronic obstructive pulmonary disease].
    Chen YR; Dai AG; Hu RC; Kong CC
    Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2012 May; 28(3):234-8. PubMed ID: 22860423
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients.
    Kroeze SG; Vermaat JS; van Brussel A; van Melick HH; Voest EE; Jonges TG; van Diest PJ; Hinrichs J; Bosch JL; Jans JJ
    Eur J Cancer; 2010 Dec; 46(18):3375-82. PubMed ID: 20709525
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH).
    Flagg SC; Martin CB; Taabazuing CY; Holmes BE; Knapp MJ
    J Inorg Biochem; 2012 Aug; 113():25-30. PubMed ID: 22687491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
    Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
    J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia.
    Fujita N; Markova D; Anderson DG; Chiba K; Toyama Y; Shapiro IM; Risbud MV
    J Biol Chem; 2012 May; 287(20):16975-86. PubMed ID: 22451659
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients.
    Peurala E; Koivunen P; Bloigu R; Haapasaari KM; Jukkola-Vuorinen A
    Breast Cancer Res Treat; 2012 May; 133(1):179-88. PubMed ID: 21877141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Low nuclear expression of HIF-hydroxylases PHD2/EGLN1 and PHD3/EGLN3 are associated with poor recurrence-free survival in clear cell renal cell carcinoma.
    Luomala L; Mattila K; Vainio P; Nisén H; Pellinen T; Lohi J; Laajala TD; Järvinen P; Koskenniemi AR; Jaakkola P; Mirtti T
    Cancer Med; 2024 Feb; 13(3):e6998. PubMed ID: 38400673
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivation of HIF-prolyl 4-hydroxylases 1, 2 and 3 in NG2-expressing cells induces HIF2-mediated neurovascular expansion independent of erythropoietin.
    Urrutia AA; Guan N; Mesa-Ciller C; Afzal A; Davidoff O; Haase VH
    Acta Physiol (Oxf); 2021 Jan; 231(1):e13547. PubMed ID: 32846048
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.
    Jokilehto T; Rantanen K; Luukkaa M; Heikkinen P; Grenman R; Minn H; Kronqvist P; Jaakkola PM
    Clin Cancer Res; 2006 Feb; 12(4):1080-7. PubMed ID: 16489060
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
    Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
    J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene Expression Levels of the Prolyl Hydroxylase Domain Proteins
    Koren A; Rijavec M; Krumpestar T; Kern I; Sadikov A; Čufer T; Korošec P
    Cancers (Basel); 2021 May; 13(10):. PubMed ID: 34065840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
    J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.