BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 21889342)

  • 1. Ferrocenyl chalcone difluoridoborates inhibit HIV-1 integrase and display low activity towards cancer and endothelial cells.
    Monserrat JP; Al-Safi RI; Tiwari KN; Quentin L; Chabot GG; Vessières A; Jaouen G; Neamati N; Hillard EA
    Bioorg Med Chem Lett; 2011 Oct; 21(20):6195-7. PubMed ID: 21889342
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
    Deng J; Sanchez T; Al-Mawsawi LQ; Dayam R; Yunes RA; Garofalo A; Bolger MB; Neamati N
    Bioorg Med Chem; 2007 Jul; 15(14):4985-5002. PubMed ID: 17502148
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.
    Ma K; Wang P; Fu W; Wan X; Zhou L; Chu Y; Ye D
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6724-7. PubMed ID: 21996518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor.
    Yang L; Xu X; Huang Y; Zhang B; Zeng C; He H; Wang C; Hu L
    Bioorg Med Chem Lett; 2010 Sep; 20(18):5469-71. PubMed ID: 20709544
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological activity of aromatic diketone derivatives as HIV-1 integrase inhibitors.
    Hu L; Li Z; Wang Z; Liu G; He X; Wang X; Zeng C
    Med Chem; 2015; 11(2):180-7. PubMed ID: 25173788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.
    Sharma H; Patil S; Sanchez TW; Neamati N; Schinazi RF; Buolamwini JK
    Bioorg Med Chem; 2011 Mar; 19(6):2030-45. PubMed ID: 21371895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Triketoacid inhibitors of HIV-integrase: a new chemotype useful for probing the integrase pharmacophore.
    Walker MA; Johnson T; Ma Z; Banville J; Remillard R; Kim O; Zhang Y; Staab A; Wong H; Torri A; Samanta H; Lin Z; Deminie C; Terry B; Krystal M; Meanwell N
    Bioorg Med Chem Lett; 2006 Jun; 16(11):2920-4. PubMed ID: 16546383
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.
    Plewe MB; Butler SL; Dress KR; Hu Q; Johnson TW; Kuehler JE; Kuki A; Lam H; Liu W; Nowlin D; Peng Q; Rahavendran SV; Tanis SP; Tran KT; Wang H; Yang A; Zhang J
    J Med Chem; 2009 Nov; 52(22):7211-9. PubMed ID: 19873974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New 2-arylnaphthalenediols and triol inhibitors of HIV-1 integrase--discovery of a new polyhydroxylated antiviral agent.
    Maurin C; Lion C; Bailly F; Touati N; Vezin H; Mbemba G; Mouscadet JF; Debyser Z; Witvrouw M; Cotelle P
    Bioorg Med Chem; 2010 Jul; 18(14):5194-201. PubMed ID: 20541944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and anti-integrase activity of catechol-DKA hybrids.
    Maurin C; Bailly F; Mbemba G; Mouscadet JF; Cotelle P
    Bioorg Med Chem; 2006 May; 14(9):2978-84. PubMed ID: 16412645
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
    Al-Mawsawi LQ; Dayam R; Taheri L; Witvrouw M; Debyser Z; Neamati N
    Bioorg Med Chem Lett; 2007 Dec; 17(23):6472-5. PubMed ID: 17950601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of inhibitors to block interactions of HIV-1 integrase with human LEDGF/p75 via structure-based virtual screening and bioassays.
    Hu G; Li X; Zhang X; Li Y; Ma L; Yang LM; Liu G; Li W; Huang J; Shen X; Hu L; Zheng YT; Tang Y
    J Med Chem; 2012 Nov; 55(22):10108-17. PubMed ID: 23046280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of N-methylpyrimidone derivatives as HIV-1 integrase inhibitors.
    Wang Y; Rong J; Zhang B; Hu L; Wang X; Zeng C
    Bioorg Med Chem; 2015 Feb; 23(4):735-41. PubMed ID: 25618597
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
    Wang P; Liu C; Sanches T; Zhong Y; Liu B; Xiong J; Neamati N; Zhao G
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4574-8. PubMed ID: 19625188
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors.
    Langford HM; Williams PD; Homnick CF; Vacca JP; Felock PJ; Stillmock KA; Witmer MV; Hazuda DJ; Gabryelski LJ; Schleif WA
    Bioorg Med Chem Lett; 2008 Jan; 18(2):721-5. PubMed ID: 18078751
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, antiviral, and anti-HIV-1 integrase activities of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines.
    Brzozowski Z; Saczewski F; Sanchez T; Kuo CL; Gdaniec M; Neamati N
    Bioorg Med Chem; 2004 Jul; 12(13):3663-72. PubMed ID: 15186851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Docking-based 3D-QSAR study of HIV-1 integrase inhibitors.
    Gupta P; Roy N; Garg P
    Eur J Med Chem; 2009 Nov; 44(11):4276-87. PubMed ID: 19647906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of HIV-1 integrase activity by single-stranded oligonucleotides and their conjugates with eosin.
    Korolev S; Knyazhanskaya E; Anisenko A; Tashlitskii V; Zatsepin TS; Gottikh M; Agapkina J
    Nucleosides Nucleotides Nucleic Acids; 2011; 30(7-8):651-66. PubMed ID: 21888554
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors.
    Rajamaki S; Innitzer A; Falciani C; Tintori C; Christ F; Witvrouw M; Debyser Z; Massa S; Botta M
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3615-8. PubMed ID: 19447621
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resistance to HIV-1 integrase inhibitors: A structural perspective.
    Mouscadet JF; Delelis O; Marcelin AG; Tchertanov L
    Drug Resist Updat; 2010; 13(4-5):139-50. PubMed ID: 20570551
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.