These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 21890734)

  • 21. In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism.
    Yu J; Brown DG; Burdette D
    Drug Metab Dispos; 2010 Oct; 38(10):1767-78. PubMed ID: 20595377
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives.
    Fujioka K; Casida JE
    Chem Res Toxicol; 2007 Aug; 20(8):1211-7. PubMed ID: 17645302
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s.
    Wen B; Ma L; Zhu M
    Chem Biol Interact; 2008 May; 173(1):59-67. PubMed ID: 18359012
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Bioactivation of flutamide metabolites by human liver microsomes.
    Kang P; Dalvie D; Smith E; Zhou S; Deese A; Nieman JA
    Drug Metab Dispos; 2008 Jul; 36(7):1425-37. PubMed ID: 18411402
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism.
    Madsen KG; Olsen J; Skonberg C; Hansen SH; Jurva U
    Chem Res Toxicol; 2007 May; 20(5):821-31. PubMed ID: 17447796
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues.
    Soglia JR; Contillo LG; Kalgutkar AS; Zhao S; Hop CE; Boyd JG; Cole MJ
    Chem Res Toxicol; 2006 Mar; 19(3):480-90. PubMed ID: 16544956
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Metabolism and bioactivation of 3-methylindole by human liver microsomes.
    Yan Z; Easterwood LM; Maher N; Torres R; Huebert N; Yost GS
    Chem Res Toxicol; 2007 Jan; 20(1):140-8. PubMed ID: 17226936
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Trimethoprim: novel reactive intermediates and bioactivation pathways by cytochrome p450s.
    Damsten MC; de Vlieger JS; Niessen WM; Irth H; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2008 Nov; 21(11):2181-7. PubMed ID: 18816075
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites.
    Tang W; Stearns RA; Bandiera SM; Zhang Y; Raab C; Braun MP; Dean DC; Pang J; Leung KH; Doss GA; Strauss JR; Kwei GY; Rushmore TH; Chiu SH; Baillie TA
    Drug Metab Dispos; 1999 Mar; 27(3):365-72. PubMed ID: 10064567
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1.
    Ross MK; Pegram RA
    Toxicol Appl Pharmacol; 2004 Mar; 195(2):166-81. PubMed ID: 14998683
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Glutathione transferase theta 1-1-dependent metabolism of the water disinfection byproduct bromodichloromethane.
    Ross MK; Pegram RA
    Chem Res Toxicol; 2003 Feb; 16(2):216-26. PubMed ID: 12588193
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s.
    Wen B; Zhou M
    Chem Biol Interact; 2009 Oct; 181(2):220-6. PubMed ID: 19482014
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Enzymatic and nonenzymatic synthesis of glutathione conjugates: application to the understanding of a parasite's defense system and alternative to the discovery of potent glutathione S-transferase inhibitors.
    Lo WJ; Chiou YC; Hsu YT; Lam WS; Chang MY; Jao SC; Li WS
    Bioconjug Chem; 2007; 18(1):109-20. PubMed ID: 17226963
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification and quantification of glutathione adducts of clozapine using ultra-high-performance liquid chromatography with orthogonal acceleration time-of-flight mass spectrometry and inductively coupled plasma mass spectrometry.
    MacDonald C; Smith C; Michopoulos F; Weaver R; Wilson ID
    Rapid Commun Mass Spectrom; 2011 Jul; 25(13):1787-93. PubMed ID: 21638353
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases.
    Venkataraman H; den Braver MW; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2014 Dec; 27(12):2071-81. PubMed ID: 25372302
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Metabolism and bioactivation of clozapine by human liver in vitro.
    Pirmohamed M; Williams D; Madden S; Templeton E; Park BK
    J Pharmacol Exp Ther; 1995 Mar; 272(3):984-90. PubMed ID: 7891353
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Bioactivation of glafenine by human liver microsomes and peroxidases: identification of electrophilic iminoquinone species and GSH conjugates.
    Wen B; Moore DJ
    Drug Metab Dispos; 2011 Sep; 39(9):1511-21. PubMed ID: 21628497
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high-resolution mass spectrometry and mass defect filtering.
    Zhu M; Ma L; Zhang H; Humphreys WG
    Anal Chem; 2007 Nov; 79(21):8333-41. PubMed ID: 17918967
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mass spectrometric characterization of protein adducts of multiple P450-dependent reactive intermediates of diclofenac to human glutathione-S-transferase P1-1.
    Boerma JS; Dragovic S; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2012 Nov; 25(11):2532-41. PubMed ID: 22998212
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Glutathione trapping of reactive drug metabolites produced by biomimetic metalloporphyrin catalysts.
    Lassila T; Mattila S; Turpeinen M; Tolonen A
    Rapid Commun Mass Spectrom; 2015 Mar; 29(6):521-32. PubMed ID: 26160418
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.