168 related articles for article (PubMed ID: 21894088)
1. Synthesis and SAR study of novel peptide aldehydes as inhibitors of 20S proteasome.
Ma Y; Xu B; Fang Y; Yang Z; Cui J; Zhang L; Zhang L
Molecules; 2011 Sep; 16(9):7551-64. PubMed ID: 21894088
[TBL] [Abstract][Full Text] [Related]
2. Covalent complexes of proteasome model with peptide aldehyde inhibitors MG132 and MG101: docking and molecular dynamics study.
Zhang S; Shi Y; Jin H; Liu Z; Zhang L; Zhang L
J Mol Model; 2009 Dec; 15(12):1481-90. PubMed ID: 19440739
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.
Blackburn C; Gigstad KM; Hales P; Garcia K; Jones M; Bruzzese FJ; Barrett C; Liu JX; Soucy TA; Sappal DS; Bump N; Olhava EJ; Fleming P; Dick LR; Tsu C; Sintchak MD; Blank JL
Biochem J; 2010 Sep; 430(3):461-76. PubMed ID: 20632995
[TBL] [Abstract][Full Text] [Related]
4. Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and cellular properties of potent, selective proteasome inhibitors.
Rydzewski RM; Burrill L; Mendonca R; Palmer JT; Rice M; Tahilramani R; Bass KE; Leung L; Gjerstad E; Janc JW; Pan L
J Med Chem; 2006 May; 49(10):2953-68. PubMed ID: 16686537
[TBL] [Abstract][Full Text] [Related]
5. Preliminary studies of new proteasome inhibitors in the tumor targeting approach: synthesis and in vitro cytotoxicity.
Vivier M; Jarrousse AS; Bouchon B; Galmier MJ; Auzeloux P; Sauzieres J; Madelmont JC
J Med Chem; 2005 Oct; 48(21):6731-40. PubMed ID: 16220988
[TBL] [Abstract][Full Text] [Related]
6. 3D-QSAR studies on tripeptide aldehyde inhibitors of proteasome using CoMFA and CoMSIA methods.
Zhu YQ; Pei JF; Liu ZM; Lai LH; Cui JR; Li RT
Bioorg Med Chem; 2006 Mar; 14(5):1483-96. PubMed ID: 16256351
[TBL] [Abstract][Full Text] [Related]
7. [Design, synthesis and biological assay of novel tripeptidic tetrazoles as inhibitors of 20S proteasome].
Ma YH; Xu B; Cui JR; Yang ZJ; Zhang LR; Zhang LH
Yao Xue Xue Bao; 2012 Apr; 47(4):472-8. PubMed ID: 22799029
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of naphthoquinone analogs as a novel class of proteasome inhibitors.
Lawrence HR; Kazi A; Luo Y; Kendig R; Ge Y; Jain S; Daniel K; Santiago D; Guida WC; Sebti SM
Bioorg Med Chem; 2010 Aug; 18(15):5576-92. PubMed ID: 20621484
[TBL] [Abstract][Full Text] [Related]
9. Modeling of the binding mode of a non-covalent inhibitor of the 20S proteasome. Application to structure-based analogue design.
Furet P; Imbach P; Fürst P; Lang M; Noorani M; Zimmermann J; García-Echeverria C
Bioorg Med Chem Lett; 2001 May; 11(10):1321-4. PubMed ID: 11392546
[TBL] [Abstract][Full Text] [Related]
10. Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes.
Grover A; Shandilya A; Bisaria VS; Sundar D
BMC Genomics; 2010 Dec; 11 Suppl 4(Suppl 4):S15. PubMed ID: 21143798
[TBL] [Abstract][Full Text] [Related]
11. Proteasome inhibitors; synthesis and activity of arecoline oxide tripeptide derivatives.
Marastoni M; McDonald J; Baldisserotto A; Canella A; De Risi C; Pollini GP; Tomatis R
Bioorg Med Chem Lett; 2004 Apr; 14(8):1965-8. PubMed ID: 15050638
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and
Corrigan TS; Lotti Diaz LM; Border SE; Ratigan SC; Kasper KQ; Sojka D; Fajtova P; Caffrey CR; Salvesen GS; McElroy CA; Hadad CM; Doğan Ekici Ö
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1387-1402. PubMed ID: 32633155
[TBL] [Abstract][Full Text] [Related]
13. A new series of N5 derivatives of the 1,1,5-trimethyl furo[3,4-c]pyridine-3,4-dione (cerpegin) selectively inhibits the post-acid activity of mammalian 20S proteasomes.
Pham TH; Hovhannisyan A; Bouvier D; Tian L; Reboud-Ravaux M; Melikyan G; Bouvier-Durand M
Bioorg Med Chem Lett; 2012 Jun; 22(11):3822-7. PubMed ID: 22560566
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and activity of tyropeptin A derivatives as potent and selective inhibitors of mammalian 20S proteasome.
Momose I; Umezawa Y; Hirosawa S; Iijima M; Iinuma H; Ikeda D
Biosci Biotechnol Biochem; 2005 Sep; 69(9):1733-42. PubMed ID: 16195592
[TBL] [Abstract][Full Text] [Related]
15. Pharmacophore modeling, docking studies, and synthesis of novel dipeptide proteasome inhibitors containing boron atoms.
Lei M; Zhao X; Wang Z; Zhu Y
J Chem Inf Model; 2009 Sep; 49(9):2092-100. PubMed ID: 19691298
[TBL] [Abstract][Full Text] [Related]
16. Kinetic studies of the branched chain amino acid preferring peptidase activity of the 20S proteasome: development of a continuous assay and inhibition by tripeptide aldehydes and clasto-lactacystin beta-lactone.
McCormack TA; Cruikshank AA; Grenier L; Melandri FD; Nunes SL; Plamondon L; Stein RL; Dick LR
Biochemistry; 1998 May; 37(21):7792-800. PubMed ID: 9601040
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of peptide aldehydes via enzymatic acylation of amino aldehyde derivatives.
Voyushina TL; Potetinova JV; Milgotina EI; Stepanov VM
Bioorg Med Chem; 1999 Dec; 7(12):2953-9. PubMed ID: 10658601
[TBL] [Abstract][Full Text] [Related]
18. Structure-activity relationship study of peptidomimetic aldehydes as enterovirus 71 3C protease inhibitors.
Zhai Y; Ma Y; Ma F; Nie Q; Ren X; Wang Y; Shang L; Yin Z
Eur J Med Chem; 2016 Nov; 124():559-573. PubMed ID: 27614190
[TBL] [Abstract][Full Text] [Related]
19. Cleavage of Pro-X and Glu-X bonds catalyzed by the branched chain amino acid preferring activity of the bovine pituitary multicatalytic proteinase complex (20S proteasome).
Cardozo C; Chen WE; Wilk S
Arch Biochem Biophys; 1996 Oct; 334(1):113-20. PubMed ID: 8837746
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel non-covalent inhibitors selective to the β5-subunit of the human 20S proteasome.
Xu K; Wang K; Yang Y; Yan DA; Huang L; Chen CH; Xiao Z
Eur J Med Chem; 2015 Jun; 98():61-8. PubMed ID: 26005024
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
