These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 21895724)

  • 1. A dual mechanism for I(Ks) current reduction by the pathogenic mutation KCNQ1-S277L.
    Chen J; Weber M; Um SY; Walsh CA; Tang Y; McDonald TV
    Pacing Clin Electrophysiol; 2011 Dec; 34(12):1652-64. PubMed ID: 21895724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability.
    Aidery P; Kisselbach J; Schweizer PA; Becker R; Katus HA; Thomas D
    Biochim Biophys Acta; 2011 Apr; 1812(4):488-94. PubMed ID: 21241800
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trafficking-deficient long QT syndrome mutation KCNQ1-T587M confers severe clinical phenotype by impairment of KCNH2 membrane localization: evidence for clinically significant IKr-IKs alpha-subunit interaction.
    Biliczki P; Girmatsion Z; Brandes RP; Harenkamp S; Pitard B; Charpentier F; Hébert TE; Hohnloser SH; Baró I; Nattel S; Ehrlich JR
    Heart Rhythm; 2009 Dec; 6(12):1792-801. PubMed ID: 19959132
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional effects of a KCNQ1 mutation associated with the long QT syndrome.
    Boulet IR; Raes AL; Ottschytsch N; Snyders DJ
    Cardiovasc Res; 2006 Jun; 70(3):466-74. PubMed ID: 16564513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Trafficking-competent KCNQ1 variably influences the function of HERG long QT alleles.
    Hayashi K; Shuai W; Sakamoto Y; Higashida H; Yamagishi M; Kupershmidt S
    Heart Rhythm; 2010 Jul; 7(7):973-80. PubMed ID: 20348026
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport.
    Wu J; Sakaguchi T; Takenaka K; Toyoda F; Tsuji K; Matsuura H; Horie M
    J Cardiol; 2019 May; 73(5):343-350. PubMed ID: 30591322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Partially dominant mutant channel defect corresponding with intermediate LQT2 phenotype.
    Krishnan Y; Zheng R; Walsh C; Tang Y; McDonald TV
    Pacing Clin Electrophysiol; 2012 Jan; 35(1):3-16. PubMed ID: 21951015
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Long QT syndrome-associated mutations in KCNQ1 and KCNE1 subunits disrupt normal endosomal recycling of IKs channels.
    Seebohm G; Strutz-Seebohm N; Ureche ON; Henrion U; Baltaev R; Mack AF; Korniychuk G; Steinke K; Tapken D; Pfeufer A; Kääb S; Bucci C; Attali B; Merot J; Tavare JM; Hoppe UC; Sanguinetti MC; Lang F
    Circ Res; 2008 Dec; 103(12):1451-7. PubMed ID: 19008479
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biophysical characteristics of a new mutation on the KCNQ1 potassium channel (L251P) causing long QT syndrome.
    Deschênes D; Acharfi S; Pouliot V; Hegele R; Krahn A; Daleau P; Chahine M
    Can J Physiol Pharmacol; 2003 Feb; 81(2):129-34. PubMed ID: 12710526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Action potential clamp and mefloquine sensitivity of recombinant 'I KS' channels incorporating the V307L KCNQ1 mutation.
    El Harchi A; McPate MJ; Zhang YH; Zhang H; Hancox JC
    J Physiol Pharmacol; 2010 Apr; 61(2):123-31. PubMed ID: 20436212
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arrhythmia formation in subclinical ("silent") long QT syndrome requires multiple insults: quantitative mechanistic study using the KCNQ1 mutation Q357R as example.
    O'Hara T; Rudy Y
    Heart Rhythm; 2012 Feb; 9(2):275-82. PubMed ID: 21952006
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Long QT syndrome-associated mutations in the voltage sensor of I(Ks) channels.
    Henrion U; Strutz-Seebohm N; Duszenko M; Lang F; Seebohm G
    Cell Physiol Biochem; 2009; 24(1-2):11-6. PubMed ID: 19590188
    [TBL] [Abstract][Full Text] [Related]  

  • 13. KCNQ1 and KCNH2 mutations associated with long QT syndrome in a Chinese population.
    Liu W; Yang J; Hu D; Kang C; Li C; Zhang S; Li P; Chen Z; Qin X; Ying K; Li Y; Li Y; Li Z; Cheng X; Li L; Qi Y; Chen S; Wang Q
    Hum Mutat; 2002 Dec; 20(6):475-6. PubMed ID: 12442276
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction between the cardiac rapidly (IKr) and slowly (IKs) activating delayed rectifier potassium channels revealed by low K+-induced hERG endocytic degradation.
    Guo J; Wang T; Yang T; Xu J; Li W; Fridman MD; Fisher JT; Zhang S
    J Biol Chem; 2011 Oct; 286(40):34664-74. PubMed ID: 21844197
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms.
    Aromolaran AS; Subramanyam P; Chang DD; Kobertz WR; Colecraft HM
    Cardiovasc Res; 2014 Dec; 104(3):501-11. PubMed ID: 25344363
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes.
    Li W; Du R; Wang QF; Tian L; Yang JG; Song ZF
    Biochem Biophys Res Commun; 2009 May; 383(2):206-9. PubMed ID: 19348785
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of disease pathogenesis in long QT syndrome type 5.
    Harmer SC; Wilson AJ; Aldridge R; Tinker A
    Am J Physiol Cell Physiol; 2010 Feb; 298(2):C263-73. PubMed ID: 19907016
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a novel mutant KCNQ1 channel subunit lacking a large part of the C-terminal domain.
    Kimoto K; Kinoshita K; Yokoyama T; Hata Y; Komatsu T; Tsushima E; Nishide K; Yamaguchi Y; Mizumaki K; Tabata T; Inoue H; Nishida N; Fukurotani K
    Biochem Biophys Res Commun; 2013 Oct; 440(2):283-8. PubMed ID: 24070608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A challenge for mutation specific risk stratification in long QT syndrome type 1.
    Yagi N; Itoh H; Hisamatsu T; Tomita Y; Kimura H; Fujii Y; Makiyama T; Horie M; Ohno S
    J Cardiol; 2018 Jul; 72(1):56-65. PubMed ID: 29439887
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Partial restoration of the long QT syndrome associated KCNQ1 A341V mutant by the KCNE1 β-subunit.
    Mikuni I; Torres CG; Bienengraeber MW; Kwok WM
    Biochim Biophys Acta; 2011 Dec; 1810(12):1285-93. PubMed ID: 21854832
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.