223 related articles for article (PubMed ID: 21898832)
1. Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosis.
Green KD; Chen W; Garneau-Tsodikova S
ChemMedChem; 2012 Jan; 7(1):73-7. PubMed ID: 21898832
[No Abstract] [Full Text] [Related]
2. Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis.
Green KD; Punetha A; Hou C; Garneau-Tsodikova S; Tsodikov OV
ACS Infect Dis; 2019 Oct; 5(10):1772-1778. PubMed ID: 31433614
[TBL] [Abstract][Full Text] [Related]
3. Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis.
Ngo HX; Green KD; Gajadeera CS; Willby MJ; Holbrook SYL; Hou C; Garzan A; Mayhoub AS; Posey JE; Tsodikov OV; Garneau-Tsodikova S
ACS Infect Dis; 2018 Jun; 4(6):1030-1040. PubMed ID: 29601176
[TBL] [Abstract][Full Text] [Related]
4. Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from
Punetha A; Ngo HX; Holbrook SYL; Green KD; Willby MJ; Bonnett SA; Krieger K; Dennis EK; Posey JE; Parish T; Tsodikov OV; Garneau-Tsodikova S
ACS Chem Biol; 2020 Jun; 15(6):1581-1594. PubMed ID: 32421305
[TBL] [Abstract][Full Text] [Related]
5. Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.
Willby MJ; Green KD; Gajadeera CS; Hou C; Tsodikov OV; Posey JE; Garneau-Tsodikova S
ACS Chem Biol; 2016 Jun; 11(6):1639-46. PubMed ID: 27010218
[TBL] [Abstract][Full Text] [Related]
6. Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors.
Garzan A; Willby MJ; Ngo HX; Gajadeera CS; Green KD; Holbrook SY; Hou C; Posey JE; Tsodikov OV; Garneau-Tsodikova S
ACS Infect Dis; 2017 Apr; 3(4):302-309. PubMed ID: 28192916
[TBL] [Abstract][Full Text] [Related]
7. Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis.
Jennings BC; Labby KJ; Green KD; Garneau-Tsodikova S
Biochemistry; 2013 Jul; 52(30):5125-32. PubMed ID: 23837529
[TBL] [Abstract][Full Text] [Related]
8. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.
Chen W; Biswas T; Porter VR; Tsodikov OV; Garneau-Tsodikova S
Proc Natl Acad Sci U S A; 2011 Jun; 108(24):9804-8. PubMed ID: 21628583
[TBL] [Abstract][Full Text] [Related]
9. A consensus reverse docking approach for identification of a competitive inhibitor of acetyltransferase enhanced intracellular survival protein from Mycobacterium tuberculosis.
Santos-Júnior PFDS; Batista VM; Nascimento IJDS; Nunes IC; Silva LR; Costa CACB; Freitas JD; Quintans-Júnior LJ; Araújo-Júnior JX; Freitas MEG; Zhan P; Green KD; Garneau-Tsodikova S; Mendonça-Júnior FJB; Rodrigues-Junior VS; Silva-Júnior EFD
Bioorg Med Chem; 2024 Jun; 108():117774. PubMed ID: 38833750
[TBL] [Abstract][Full Text] [Related]
10. Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis.
Pricer RE; Houghton JL; Green KD; Mayhoub AS; Garneau-Tsodikova S
Mol Biosyst; 2012 Oct; 8(12):3305-13. PubMed ID: 23090428
[TBL] [Abstract][Full Text] [Related]
11. Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs.
Pang AH; Green KD; Punetha A; Thamban Chandrika N; Howard KC; Garneau-Tsodikova S; Tsodikov OV
Biochemistry; 2023 Feb; 62(3):710-721. PubMed ID: 36657084
[TBL] [Abstract][Full Text] [Related]
12. Andrographolide: A potent antituberculosis compound that targets Aminoglycoside 2'-N-acetyltransferase in Mycobacterium tuberculosis.
Prabu A; Hassan S; Prabuseenivasan ; Shainaba AS; Hanna LE; Kumar V
J Mol Graph Model; 2015 Sep; 61():133-40. PubMed ID: 26245695
[TBL] [Abstract][Full Text] [Related]
13. Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections.
Labby KJ; Garneau-Tsodikova S
Future Med Chem; 2013 Jul; 5(11):1285-309. PubMed ID: 23859208
[TBL] [Abstract][Full Text] [Related]
14. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis.
Garzan A; Willby MJ; Green KD; Gajadeera CS; Hou C; Tsodikov OV; Posey JE; Garneau-Tsodikova S
J Med Chem; 2016 Dec; 59(23):10619-10628. PubMed ID: 27933949
[TBL] [Abstract][Full Text] [Related]
15. Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis.
Zaunbrecher MA; Sikes RD; Metchock B; Shinnick TM; Posey JE
Proc Natl Acad Sci U S A; 2009 Nov; 106(47):20004-9. PubMed ID: 19906990
[TBL] [Abstract][Full Text] [Related]
16. High-throughput screen identifies small molecule inhibitors targeting acetyltransferase activity of Mycobacterium tuberculosis GlmU.
Rani C; Mehra R; Sharma R; Chib R; Wazir P; Nargotra A; Khan IA
Tuberculosis (Edinb); 2015 Dec; 95(6):664-677. PubMed ID: 26318557
[TBL] [Abstract][Full Text] [Related]
17. A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Inoyama D; Awasthi D; Capodagli GC; Tsotetsi K; Sukheja P; Zimmerman M; Li SG; Jadhav R; Russo R; Wang X; Grady C; Richmann T; Shrestha R; Li L; Ahn YM; Ho Liang HP; Mina M; Park S; Perlin DS; Connell N; Dartois V; Alland D; Neiditch MB; Kumar P; Freundlich JS
Cell Chem Biol; 2020 May; 27(5):560-570.e10. PubMed ID: 32197094
[TBL] [Abstract][Full Text] [Related]
18.
Borthwick JA; Alemparte C; Wall I; Whitehurst BC; Argyrou A; Burley G; de Dios-Anton P; Guijarro L; Monteiro MC; Ortega F; Suckling CJ; Pichel JC; Cacho M; Young RJ
J Med Chem; 2020 Mar; 63(5):2557-2576. PubMed ID: 31922409
[TBL] [Abstract][Full Text] [Related]
19. eis Promoter C14G and C15G Mutations Do Not Confer Kanamycin Resistance in Mycobacterium tuberculosis.
Pholwat S; Stroup S; Heysell S; Ogarkov O; Zhdanova S; Ramakrishnan G; Houpt E
Antimicrob Agents Chemother; 2016 Dec; 60(12):7522-7523. PubMed ID: 27736762
[TBL] [Abstract][Full Text] [Related]
20. [Advances in research for resistance mechanisms of aminoglycoside and Cyclic peptide antibiotic to Mycobacterium tuberculosis].
Song YH; Gao MQ
Zhonghua Jie He He Hu Xi Za Zhi; 2012 Jul; 35(7):531-3. PubMed ID: 22931808
[No Abstract] [Full Text] [Related]
[Next] [New Search]
