BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 21900744)

  • 1. SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells.
    Van Meter M; Mao Z; Gorbunova V; Seluanov A
    Cell Cycle; 2011 Sep; 10(18):3153-8. PubMed ID: 21900744
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair.
    Van Meter M; Mao Z; Gorbunova V; Seluanov A
    Aging (Albany NY); 2011 Sep; 3(9):829-35. PubMed ID: 21946623
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptin induces apoptosis by changing the equilibrium between the stability of TAp73 and ΔNp73 isoforms through ubiquitin ligase PIR2.
    Taebunpakul P; Sayan BS; Flinterman M; Klanrit P; Gäken J; Odell EW; Melino G; Tavassoli M
    Apoptosis; 2012 Aug; 17(8):762-76. PubMed ID: 22484480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The PARP inhibitor PJ34 causes a PARP1-independent, p21 dependent mitotic arrest.
    Madison DL; Stauffer D; Lundblad JR
    DNA Repair (Amst); 2011 Oct; 10(10):1003-13. PubMed ID: 21840268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SIRT6 promotes DNA repair under stress by activating PARP1.
    Mao Z; Hine C; Tian X; Van Meter M; Au M; Vaidya A; Seluanov A; Gorbunova V
    Science; 2011 Jun; 332(6036):1443-6. PubMed ID: 21680843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Poly(ADP-ribose) Polymerase-1 Enhances Gene Expression of Selected Sirtuins and APP Cleaving Enzymes in Amyloid Beta Cytotoxicity.
    Wencel PL; Lukiw WJ; Strosznajder JB; Strosznajder RP
    Mol Neurobiol; 2018 Jun; 55(6):4612-4623. PubMed ID: 28698968
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner.
    Xu Z; Zhang L; Zhang W; Meng D; Zhang H; Jiang Y; Xu X; Van Meter M; Seluanov A; Gorbunova V; Mao Z
    Cell Cycle; 2015; 14(2):269-76. PubMed ID: 25607651
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway.
    Kim EJ; Juhnn YS
    J Biol Chem; 2015 Apr; 290(15):9604-13. PubMed ID: 25713071
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shikonin causes apoptosis by up-regulating p73 and down-regulating ICBP90 in human cancer cells.
    Jang SY; Hong D; Jeong SY; Kim JH
    Biochem Biophys Res Commun; 2015 Sep; 465(1):71-6. PubMed ID: 26235879
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress.
    Lehman JA; Waning DL; Batuello CN; Cipriano R; Kadakia MP; Mayo LD
    J Biol Chem; 2011 Oct; 286(42):36631-40. PubMed ID: 21873427
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation.
    Koida N; Ozaki T; Yamamoto H; Ono S; Koda T; Ando K; Okoshi R; Kamijo T; Omura K; Nakagawara A
    J Biol Chem; 2008 Mar; 283(13):8555-63. PubMed ID: 18174154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
    Yoon JH; Ahn SG; Lee BH; Jung SH; Oh SH
    Biochem Pharmacol; 2012 Mar; 83(6):747-57. PubMed ID: 22226932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth.
    Zhang Y; Zhang C; Li J; Jiang M; Guo S; Yang G; Zhang L; Wang F; Yi S; Wang J; Fu Y; Zhang Y
    Cell Commun Signal; 2022 Jun; 20(1):93. PubMed ID: 35715817
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria.
    John K; Alla V; Meier C; Pützer BM
    Cell Death Differ; 2011 May; 18(5):874-86. PubMed ID: 21127500
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein-Dependent Apoptotic Pathway.
    Ran LK; Chen Y; Zhang ZZ; Tao NN; Ren JH; Zhou L; Tang H; Chen X; Chen K; Li WY; Huang AL; Chen J
    Clin Cancer Res; 2016 Jul; 22(13):3372-82. PubMed ID: 26861461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SIRT6 regulates the proliferation and apoptosis of hepatocellular carcinoma via the ERK1/2 signaling pathway.
    Zhang C; Yu Y; Huang Q; Tang K
    Mol Med Rep; 2019 Aug; 20(2):1575-1582. PubMed ID: 31257493
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73.
    Thangasamy T; Sittadjody S; Mitchell GC; Mendoza EE; Radhakrishnan VM; Limesand KH; Burd R
    BMC Cancer; 2010 Jun; 10():282. PubMed ID: 20540768
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity.
    Dai JM; Wang ZY; Sun DC; Lin RX; Wang SQ
    J Cell Physiol; 2007 Jan; 210(1):161-6. PubMed ID: 16998810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple regulatory layers of SREBP1/2 by SIRT6.
    Elhanati S; Kanfi Y; Varvak A; Roichman A; Carmel-Gross I; Barth S; Gibor G; Cohen HY
    Cell Rep; 2013 Sep; 4(5):905-12. PubMed ID: 24012758
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells.
    Okuda A; Kurokawa S; Takehashi M; Maeda A; Fukuda K; Kubo Y; Nogusa H; Takatani-Nakase T; Okuda S; Ueda K; Tanaka S
    BMC Neurosci; 2017 Jan; 18(1):14. PubMed ID: 28095779
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.