231 related articles for article (PubMed ID: 21903589)
1. Oncogenic ras-induced down-regulation of pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells.
Yoo BH; Wang Y; Erdogan M; Sasazuki T; Shirasawa S; Corcos L; Sabapathy K; Rosen KV
J Biol Chem; 2011 Nov; 286(45):38894-903. PubMed ID: 21903589
[TBL] [Abstract][Full Text] [Related]
2. Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm.
Liu Z; Li H; Derouet M; Berezkin A; Sasazuki T; Shirasawa S; Rosen K
J Biol Chem; 2006 May; 281(21):14738-47. PubMed ID: 16461771
[TBL] [Abstract][Full Text] [Related]
3. Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells.
Yoo BH; Berezkin A; Wang Y; Zagryazhskaya A; Rosen KV
Int J Cancer; 2012 Jul; 131(2):357-66. PubMed ID: 21834075
[TBL] [Abstract][Full Text] [Related]
4. Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells.
Rosen K; Rak J; Leung T; Dean NM; Kerbel RS; Filmus J
J Cell Biol; 2000 Apr; 149(2):447-56. PubMed ID: 10769035
[TBL] [Abstract][Full Text] [Related]
5. Downregulation of the pro-apoptotic protein Bak is required for the ras-induced transformation of intestinal epithelial cells.
Rosen K; Rak J; Jin J; Kerbel RS; Newman MJ; Filmus J
Curr Biol; 1998 Dec; 8(24):1331-4. PubMed ID: 9843689
[TBL] [Abstract][Full Text] [Related]
6. ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.
Liu Z; Li H; Derouet M; Filmus J; LaCasse EC; Korneluk RG; Kerbel RS; Rosen KV
J Biol Chem; 2005 Nov; 280(45):37383-92. PubMed ID: 16115895
[TBL] [Abstract][Full Text] [Related]
7. Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells.
Yoo BH; Wu X; Li Y; Haniff M; Sasazuki T; Shirasawa S; Eskelinen EL; Rosen KV
J Biol Chem; 2010 Feb; 285(8):5438-49. PubMed ID: 19778902
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis.
Yoo BH; Wu X; Derouet M; Haniff M; Eskelinen EL; Rosen K
Autophagy; 2009 Nov; 5(8):1166-79. PubMed ID: 19901551
[TBL] [Abstract][Full Text] [Related]
9. ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells.
Khan IA; Yoo BH; Masson O; Baron S; Corkery D; Dellaire G; Attardi LD; Rosen KV
Oncogene; 2016 Nov; 35(44):5759-5769. PubMed ID: 27109096
[TBL] [Abstract][Full Text] [Related]
10. p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.
Yamauchi S; Hou YY; Guo AK; Hirata H; Nakajima W; Yip AK; Yu CH; Harada I; Chiam KH; Sawada Y; Tanaka N; Kawauchi K
J Cell Biol; 2014 Mar; 204(7):1191-207. PubMed ID: 24662565
[TBL] [Abstract][Full Text] [Related]
11. Met receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions.
Pomerleau V; Landry M; Bernier J; Vachon PH; Saucier C
BMC Cancer; 2014 Apr; 14():240. PubMed ID: 24708867
[TBL] [Abstract][Full Text] [Related]
12. Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212.
Yang L; Sun M; Sun XM; Cheng GZ; Nicosia SV; Cheng JQ
J Biol Chem; 2007 Apr; 282(15):10981-7. PubMed ID: 17311912
[TBL] [Abstract][Full Text] [Related]
13. Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells.
Li H; Ray G; Yoo BH; Erdogan M; Rosen KV
J Biol Chem; 2009 Jan; 284(4):2012-22. PubMed ID: 18957423
[TBL] [Abstract][Full Text] [Related]
14. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
McFall A; Ulkü A; Lambert QT; Kusa A; Rogers-Graham K; Der CJ
Mol Cell Biol; 2001 Aug; 21(16):5488-99. PubMed ID: 11463831
[TBL] [Abstract][Full Text] [Related]
15. TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.
Oberst MD; Beberman SJ; Zhao L; Yin JJ; Ward Y; Kelly K
BMC Cancer; 2008 Jul; 8():189. PubMed ID: 18597688
[TBL] [Abstract][Full Text] [Related]
16. Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells.
Mason JA; Davison-Versagli CA; Leliaert AK; Pape DJ; McCallister C; Zuo J; Durbin SM; Buchheit CL; Zhang S; Schafer ZT
Cell Death Differ; 2016 Aug; 23(8):1271-82. PubMed ID: 26915296
[TBL] [Abstract][Full Text] [Related]
17. Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation.
Bettoun A; Joffre C; Zago G; Surdez D; Vallerand D; Gundogdu R; Sharif AA; Gomez M; Cascone I; Meunier B; White MA; Codogno P; Parrini MC; Camonis JH; Hergovich A
Oncotarget; 2016 Jul; 7(28):44142-44160. PubMed ID: 27283898
[TBL] [Abstract][Full Text] [Related]
18. Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells.
Yoo BH; Khan IA; Koomson A; Gowda P; Sasazuki T; Shirasawa S; Gujar S; Rosen KV
Autophagy; 2018; 14(1):134-151. PubMed ID: 28933585
[TBL] [Abstract][Full Text] [Related]
19. Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.
Pruitt K; Ulkü AS; Frantz K; Rojas RJ; Muniz-Medina VM; Rangnekar VM; Der CJ; Shields JM
J Biol Chem; 2005 Jun; 280(24):23363-70. PubMed ID: 15831492
[TBL] [Abstract][Full Text] [Related]
20. The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells.
Yao X; Jennings S; Ireland SK; Pham T; Temple B; Davis M; Chen R; Davenport I; Biliran H
PLoS One; 2014; 9(7):e101564. PubMed ID: 25003198
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]