181 related articles for article (PubMed ID: 21905739)
1. Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors.
Dyrager C; Möllers LN; Kjäll LK; Alao JP; Dinér P; Wallner FK; Sunnerhagen P; Grøtli M
J Med Chem; 2011 Oct; 54(20):7427-31. PubMed ID: 21905739
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of trisubstituted imidazole derivatives as inhibitors of p38alpha mitogen-activated protein kinase.
Kim DK; Lim JH; Lee JA; Dewang PM
Bioorg Med Chem Lett; 2008 Jul; 18(14):4006-10. PubMed ID: 18571921
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region.
Laufer SA; Hauser DR; Domeyer DM; Kinkel K; Liedtke AJ
J Med Chem; 2008 Jul; 51(14):4122-49. PubMed ID: 18578517
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and molecular docking studies of new furochromone derivatives as p38α MAPK inhibitors targeting human breast cancer MCF-7 cells.
Amin KM; Syam YM; Anwar MM; Ali HI; Abdel-Ghani TM; Serry AM
Bioorg Med Chem; 2017 Apr; 25(8):2423-2436. PubMed ID: 28291685
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and antitumor activity of novel dithiocarbamate substituted chromones.
Huang W; Ding Y; Miao Y; Liu MZ; Li Y; Yang GF
Eur J Med Chem; 2009 Sep; 44(9):3687-96. PubMed ID: 19410339
[TBL] [Abstract][Full Text] [Related]
6. Tri- and tetrasubstituted pyrazole derivates: regioisomerism switches activity from p38MAP kinase to important cancer kinases.
Abu Thaher B; Arnsmann M; Totzke F; Ehlert JE; Kubbutat MH; Schächtele C; Zimmermann MO; Koch P; Boeckler FM; Laufer SA
J Med Chem; 2012 Jan; 55(2):961-5. PubMed ID: 22185282
[TBL] [Abstract][Full Text] [Related]
7. Design, syntheses, and antitumor activity of novel chromone and aurone derivatives.
Huang W; Liu MZ; Li Y; Tan Y; Yang GF
Bioorg Med Chem; 2007 Aug; 15(15):5191-7. PubMed ID: 17524655
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and evaluation of novel 6-chloro-/fluorochromone derivatives as potential topoisomerase inhibitor anticancer agents.
Ishar MP; Singh G; Singh S; Sreenivasan KK; Singh G
Bioorg Med Chem Lett; 2006 Mar; 16(5):1366-70. PubMed ID: 16332438
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological evaluation of novel disubstituted dibenzosuberones as highly potent and selective inhibitors of p38 mitogen activated protein kinase.
Koeberle SC; Fischer S; Schollmeyer D; Schattel V; Grütter C; Rauh D; Laufer SA
J Med Chem; 2012 Jun; 55(12):5868-77. PubMed ID: 22676210
[TBL] [Abstract][Full Text] [Related]
10. Pyridinylquinoxalines and pyridinylpyridopyrazines as lead compounds for novel p38 alpha mitogen-activated protein kinase inhibitors.
Koch P; Jahns H; Schattel V; Goettert M; Laufer S
J Med Chem; 2010 Feb; 53(3):1128-37. PubMed ID: 20078117
[TBL] [Abstract][Full Text] [Related]
11. Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro.
Griffin RJ; Fontana G; Golding BT; Guiard S; Hardcastle IR; Leahy JJ; Martin N; Richardson C; Rigoreau L; Stockley M; Smith GC
J Med Chem; 2005 Jan; 48(2):569-85. PubMed ID: 15658870
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and SAR studies of bis-chromenone derivatives for anti-proliferative activity against human cancer cells.
Venkateswararao E; Sharma VK; Manickam M; Yun J; Jung SH
Bioorg Med Chem Lett; 2014 Nov; 24(22):5256-9. PubMed ID: 25442319
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of potent 1,2,4-trisubstituted imidazolinone derivatives with dual p38αMAPK and ERK1/2 inhibitory activity.
Awadallah FM; Abou-Seri SM; Abdulla MM; Georgey HH
Eur J Med Chem; 2015 Apr; 94():397-404. PubMed ID: 25778995
[TBL] [Abstract][Full Text] [Related]
14. Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzothiazoles.
Vasselin DA; Westwell AD; Matthews CS; Bradshaw TD; Stevens MF
J Med Chem; 2006 Jun; 49(13):3973-81. PubMed ID: 16789754
[TBL] [Abstract][Full Text] [Related]
15. N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: a novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors.
Mannion M; Raeppel S; Claridge S; Zhou N; Saavedra O; Isakovic L; Zhan L; Gaudette F; Raeppel F; Déziel R; Beaulieu N; Nguyen H; Chute I; Beaulieu C; Dupont I; Robert MF; Lefebvre S; Dubay M; Rahil J; Wang J; Ste-Croix H; Robert Macleod A; Besterman JM; Vaisburg A
Bioorg Med Chem Lett; 2009 Dec; 19(23):6552-6. PubMed ID: 19854051
[TBL] [Abstract][Full Text] [Related]
16. Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation.
Gill AL; Frederickson M; Cleasby A; Woodhead SJ; Carr MG; Woodhead AJ; Walker MT; Congreve MS; Devine LA; Tisi D; O'Reilly M; Seavers LC; Davis DJ; Curry J; Anthony R; Padova A; Murray CW; Carr RA; Jhoti H
J Med Chem; 2005 Jan; 48(2):414-26. PubMed ID: 15658855
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells.
Barve V; Ahmed F; Adsule S; Banerjee S; Kulkarni S; Katiyar P; Anson CE; Powell AK; Padhye S; Sarkar FH
J Med Chem; 2006 Jun; 49(13):3800-8. PubMed ID: 16789737
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and molecular docking study of new benzofuran and furo[3,2-g]chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors.
Amin KM; Syam YM; Anwar MM; Ali HI; Abdel-Ghani TM; Serry AM
Bioorg Chem; 2018 Feb; 76():487-500. PubMed ID: 29310080
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of α-methylidene-δ-lactones with 3,4-dihydrocoumarin skeleton.
Modranka J; Albrecht A; Jakubowski R; Krawczyk H; Różalski M; Krajewska U; Janecka A; Wyrębska A; Różalska B; Janecki T
Bioorg Med Chem; 2012 Aug; 20(16):5017-26. PubMed ID: 22789709
[TBL] [Abstract][Full Text] [Related]
20. Preparation of 3-substituted-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amines as RET kinase inhibitors.
Dinér P; Alao JP; Söderlund J; Sunnerhagen P; Grøtli M
J Med Chem; 2012 May; 55(10):4872-6. PubMed ID: 22559926
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
