223 related articles for article (PubMed ID: 21906659)
21. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation.
Cai CZ; Zhou HF; Yuan NN; Wu MY; Lee SM; Ren JY; Su HX; Lu JJ; Chen XP; Li M; Tan JQ; Lu JH
Phytomedicine; 2019 Aug; 61():152842. PubMed ID: 31048127
[TBL] [Abstract][Full Text] [Related]
22. Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synuclein.
Nakaso K; Tajima N; Ito S; Teraoka M; Yamashita A; Horikoshi Y; Kikuchi D; Mochida S; Nakashima K; Matsura T
PLoS One; 2013; 8(2):e55068. PubMed ID: 23457458
[TBL] [Abstract][Full Text] [Related]
23. Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells.
Yshii LM; Denadai-Souza A; Vasconcelos AR; Avellar MC; Scavone C
J Neuroinflammation; 2015 Oct; 12():193. PubMed ID: 26502720
[TBL] [Abstract][Full Text] [Related]
24. alpha-Synuclein fission yeast model: concentration-dependent aggregation without plasma membrane localization or toxicity.
Brandis KA; Holmes IF; England SJ; Sharma N; Kukreja L; DebBurman SK
J Mol Neurosci; 2006; 28(2):179-91. PubMed ID: 16679557
[TBL] [Abstract][Full Text] [Related]
25. Alteration of Structure and Aggregation of α-Synuclein by Familial Parkinson's Disease Associated Mutations.
Sahay S; Ghosh D; Singh PK; Maji SK
Curr Protein Pept Sci; 2017; 18(7):656-676. PubMed ID: 26972727
[TBL] [Abstract][Full Text] [Related]
26. Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.
Qiao L; Hamamichi S; Caldwell KA; Caldwell GA; Yacoubian TA; Wilson S; Xie ZL; Speake LD; Parks R; Crabtree D; Liang Q; Crimmins S; Schneider L; Uchiyama Y; Iwatsubo T; Zhou Y; Peng L; Lu Y; Standaert DG; Walls KC; Shacka JJ; Roth KA; Zhang J
Mol Brain; 2008 Nov; 1():17. PubMed ID: 19021916
[TBL] [Abstract][Full Text] [Related]
27. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo.
Mbefo MK; Fares MB; Paleologou K; Oueslati A; Yin G; Tenreiro S; Pinto M; Outeiro T; Zweckstetter M; Masliah E; Lashuel HA
J Biol Chem; 2015 Apr; 290(15):9412-27. PubMed ID: 25657004
[TBL] [Abstract][Full Text] [Related]
28. The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
Sharma N; Rao SP; Kalivendi SV
Free Radic Biol Med; 2019 May; 135():28-37. PubMed ID: 30796974
[TBL] [Abstract][Full Text] [Related]
29. Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation.
Chai YJ; Sierecki E; Tomatis VM; Gormal RS; Giles N; Morrow IC; Xia D; Götz J; Parton RG; Collins BM; Gambin Y; Meunier FA
J Cell Biol; 2016 Sep; 214(6):705-18. PubMed ID: 27597756
[TBL] [Abstract][Full Text] [Related]
30. The Parkinson's disease-related protein DJ-1 protects dopaminergic neurons in vivo and cultured cells from alpha-synuclein and 6-hydroxydopamine toxicity.
Batelli S; Invernizzi RW; Negro A; Calcagno E; Rodilossi S; Forloni G; Albani D
Neurodegener Dis; 2015; 15(1):13-23. PubMed ID: 25500798
[TBL] [Abstract][Full Text] [Related]
31. Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome.
Petroi D; Popova B; Taheri-Talesh N; Irniger S; Shahpasandzadeh H; Zweckstetter M; Outeiro TF; Braus GH
J Biol Chem; 2012 Aug; 287(33):27567-79. PubMed ID: 22722939
[TBL] [Abstract][Full Text] [Related]
32. Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K.
Choong CJ; Say YH
Neurotoxicology; 2011 Dec; 32(6):857-63. PubMed ID: 21658409
[TBL] [Abstract][Full Text] [Related]
33. Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
Machiya Y; Hara S; Arawaka S; Fukushima S; Sato H; Sakamoto M; Koyama S; Kato T
J Biol Chem; 2010 Dec; 285(52):40732-44. PubMed ID: 20959456
[TBL] [Abstract][Full Text] [Related]
34. The toxicities of A30P and A53T α-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine.
Ali A; Zhaliazka K; Dou T; Holman AP; Kurouski D
J Biol Chem; 2023 Dec; 299(12):105383. PubMed ID: 37890776
[TBL] [Abstract][Full Text] [Related]
35. C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.
Kleinknecht A; Popova B; Lázaro DF; Pinho R; Valerius O; Outeiro TF; Braus GH
PLoS Genet; 2016 Jun; 12(6):e1006098. PubMed ID: 27341336
[TBL] [Abstract][Full Text] [Related]
36. Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors.
Wislet-Gendebien S; Visanji NP; Whitehead SN; Marsilio D; Hou W; Figeys D; Fraser PE; Bennett SA; Tandon A
BMC Neurosci; 2008 Sep; 9():92. PubMed ID: 18808659
[TBL] [Abstract][Full Text] [Related]
37. Specific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated Neurotoxicity.
Qu J; Ren X; Xue F; He Y; Zhang R; Zheng Y; Huang H; Wang W; Zhang J
Cell Chem Biol; 2020 Jun; 27(6):751-762.e4. PubMed ID: 32359427
[TBL] [Abstract][Full Text] [Related]
38. Label-free detection of early oligomerization of α-synuclein and its mutants A30P/E46K through solid-state nanopores.
Li X; Tong X; Lu W; Yu D; Diao J; Zhao Q
Nanoscale; 2019 Mar; 11(13):6480-6488. PubMed ID: 30892349
[TBL] [Abstract][Full Text] [Related]
39. ATP13A2 Gene Silencing in Drosophila Affects Autophagic Degradation of A53T Mutant α-Synuclein.
Dhanushkodi NR; Abul Khair SB; Ardah MT; Haque ME
Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36675288
[TBL] [Abstract][Full Text] [Related]
40. Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
Chu Y; Dodiya H; Aebischer P; Olanow CW; Kordower JH
Neurobiol Dis; 2009 Sep; 35(3):385-98. PubMed ID: 19505575
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
