These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 21907808)

  • 1. Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
    Venskutonytė R; Frydenvang K; Gajhede M; Bunch L; Pickering DS; Kastrup JS
    J Struct Biol; 2011 Dec; 176(3):307-14. PubMed ID: 21907808
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kainate induces various domain closures in AMPA and kainate receptors.
    Venskutonytė R; Frydenvang K; Hald H; Rabassa AC; Gajhede M; Ahring PK; Kastrup JS
    Neurochem Int; 2012 Sep; 61(4):536-45. PubMed ID: 22425692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
    Møllerud S; Pinto A; Marconi L; Frydenvang K; Thorsen TS; Laulumaa S; Venskutonytė R; Winther S; Moral AMC; Tamborini L; Conti P; Pickering DS; Kastrup JS
    ACS Chem Neurosci; 2017 Sep; 8(9):2056-2064. PubMed ID: 28691798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors.
    Venskutonytė R; Frydenvang K; Valadés EA; Szymańska E; Johansen TN; Kastrup JS; Pickering DS
    ChemMedChem; 2012 Oct; 7(10):1793-8. PubMed ID: 22407805
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
    Assaf Z; Larsen AP; Venskutonytė R; Han L; Abrahamsen B; Nielsen B; Gajhede M; Kastrup JS; Jensen AA; Pickering DS; Frydenvang K; Gefflaut T; Bunch L
    J Med Chem; 2013 Feb; 56(4):1614-28. PubMed ID: 23414088
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors.
    Juknaitė L; Venskutonytė R; Assaf Z; Faure S; Gefflaut T; Aitken DJ; Nielsen B; Gajhede M; Kastrup JS; Bunch L; Frydenvang K; Pickering DS
    J Struct Biol; 2012 Oct; 180(1):39-46. PubMed ID: 22789682
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domain.
    Venskutonytė R; Larsen AP; Frydenvang K; Gajhede M; Sagot E; Assaf Z; Gefflaut T; Pickering DS; Bunch L; Kastrup JS
    ChemMedChem; 2014 Oct; 9(10):2254-9. PubMed ID: 25044437
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Assembly and Trafficking of Homomeric and Heteromeric Kainate Receptors with Impaired Ligand Binding Sites.
    Scholefield CL; Atlason PT; Jane DE; Molnár E
    Neurochem Res; 2019 Mar; 44(3):585-599. PubMed ID: 30302614
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lessons from crystal structures of kainate receptors.
    Møllerud S; Frydenvang K; Pickering DS; Kastrup JS
    Neuropharmacology; 2017 Jan; 112(Pt A):16-28. PubMed ID: 27236079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK binding sites.
    Sköld N; Nielsen B; Olsen J; Han L; Olsen L; Madsen U; Kristensen JL; Pickering DS; Johansen TN
    Bioorg Med Chem; 2014 Oct; 22(19):5368-77. PubMed ID: 25172149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains.
    Kumar J; Mayer ML
    J Mol Biol; 2010 Dec; 404(4):680-96. PubMed ID: 20951142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate.
    Kristensen O; Kristensen LB; Møllerud S; Frydenvang K; Pickering DS; Kastrup JS
    Structure; 2016 Sep; 24(9):1582-9. PubMed ID: 27524200
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.
    Mayer ML
    Neuron; 2005 Feb; 45(4):539-52. PubMed ID: 15721240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology.
    Pallesen J; Møllerud S; Frydenvang K; Pickering DS; Bornholdt J; Nielsen B; Pasini D; Han L; Marconi L; Kastrup JS; Johansen TN
    ACS Chem Neurosci; 2019 Mar; 10(3):1841-1853. PubMed ID: 30620174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding and selectivity of the marine toxin neodysiherbaine A and its synthetic analogues to GluK1 and GluK2 kainate receptors.
    Unno M; Shinohara M; Takayama K; Tanaka H; Teruya K; Doh-ura K; Sakai R; Sasaki M; Ikeda-Saito M
    J Mol Biol; 2011 Oct; 413(3):667-83. PubMed ID: 21893069
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of a glutamate-receptor ligand-binding core in complex with kainate.
    Armstrong N; Sun Y; Chen GQ; Gouaux E
    Nature; 1998 Oct; 395(6705):913-7. PubMed ID: 9804426
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate.
    Naur P; Vestergaard B; Skov LK; Egebjerg J; Gajhede M; Kastrup JS
    FEBS Lett; 2005 Feb; 579(5):1154-60. PubMed ID: 15710405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.
    Venskutonyte R; Butini S; Coccone SS; Gemma S; Brindisi M; Kumar V; Guarino E; Maramai S; Valenti S; Amir A; Valadés EA; Frydenvang K; Kastrup JS; Novellino E; Campiani G; Pickering DS
    J Med Chem; 2011 Jul; 54(13):4793-805. PubMed ID: 21619066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands.
    Szymańska E; Chałupnik P; Szczepańska K; Cuñado Moral AM; Pickering DS; Nielsen B; Johansen TN; Kieć-Kononowicz K
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5568-5572. PubMed ID: 27765511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.
    Bay Y; Venskutonytė R; Frantsen SM; Thorsen TS; Musgaard M; Frydenvang K; Francotte P; Pirotte B; Biggin PC; Kristensen AS; Boesen T; Pickering DS; Gajhede M; Kastrup JS
    FEBS J; 2024 Apr; 291(7):1506-1529. PubMed ID: 38145505
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.