These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 21907911)

  • 21. Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b.
    Jung JK; Johnson BR; Duong T; Decaire M; Uy J; Gharbaoui T; Boatman PD; Sage CR; Chen R; Richman JG; Connolly DT; Semple G
    J Med Chem; 2007 Apr; 50(7):1445-8. PubMed ID: 17358052
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A.
    Zhang Y; Schmidt RJ; Foxworthy P; Emkey R; Oler JK; Large TH; Wang H; Su EW; Mosior MK; Eacho PI; Cao G
    Biochem Biophys Res Commun; 2005 Aug; 334(2):729-32. PubMed ID: 16018973
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Langerhans cells release prostaglandin D2 in response to nicotinic acid.
    Maciejewski-Lenoir D; Richman JG; Hakak Y; Gaidarov I; Behan DP; Connolly DT
    J Invest Dermatol; 2006 Dec; 126(12):2637-46. PubMed ID: 17008871
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid.
    Pike NB
    J Clin Invest; 2005 Dec; 115(12):3400-3. PubMed ID: 16322787
    [TBL] [Abstract][Full Text] [Related]  

  • 25. 5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b.
    Skinner PJ; Webb PJ; Sage CR; Dang TH; Pride CC; Chen R; Tamura SY; Richman JG; Connolly DT; Semple G
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4207-9. PubMed ID: 19524438
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors.
    Hudson BD; Smith NJ; Milligan G
    Adv Pharmacol; 2011; 62():175-218. PubMed ID: 21907910
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing.
    Sakurai T; Davenport R; Stafford S; Grosse J; Ogawa K; Cameron J; Parton L; Sykes A; Mack S; Bousba S; Parmar A; Harrison D; Dickson L; Leveridge M; Matsui J; Barnes M
    Eur J Pharmacol; 2014 Mar; 727():1-7. PubMed ID: 24486398
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.
    Skinner PJ; Cherrier MC; Webb PJ; Shin YJ; Gharbaoui T; Lindstrom A; Hong V; Tamura SY; Dang HT; Pride CC; Chen R; Richman JG; Connolly DT; Semple G
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5620-3. PubMed ID: 17804224
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function.
    Kristiansen K
    Pharmacol Ther; 2004 Jul; 103(1):21-80. PubMed ID: 15251227
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Niacin in cardiovascular prevention: mechanisms, efficacy, and safety.
    Guyton JR
    Curr Opin Lipidol; 2007 Aug; 18(4):415-20. PubMed ID: 17620858
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.
    Tunaru S; Kero J; Schaub A; Wufka C; Blaukat A; Pfeffer K; Offermanns S
    Nat Med; 2003 Mar; 9(3):352-5. PubMed ID: 12563315
    [TBL] [Abstract][Full Text] [Related]  

  • 32. GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a.
    Imbriglio JE; Chang S; Liang R; Raghavan S; Schmidt D; Smenton A; Tria S; Schrader TO; Jung JK; Esser C; Holt TG; Wolff MS; Taggart AK; Cheng K; Carballo-Jane E; Waters MG; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4472-4. PubMed ID: 20615702
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology.
    DeWire SM; Violin JD
    Circ Res; 2011 Jul; 109(2):205-16. PubMed ID: 21737816
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Evidence for constitutive dimerization of niacin receptor subtypes.
    Mandrika I; Petrovska R; Klovins J
    Biochem Biophys Res Commun; 2010 Apr; 395(2):281-7. PubMed ID: 20380810
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.
    Shen HC; Ding FX; Deng Q; Wilsie LC; Krsmanovic ML; Taggart AK; Carballo-Jane E; Ren N; Cai TQ; Wu TJ; Wu KK; Cheng K; Chen Q; Wolff MS; Tong X; Holt TG; Waters MG; Hammond ML; Tata JR; Colletti SL
    J Med Chem; 2009 Apr; 52(8):2587-602. PubMed ID: 19309152
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2.
    Graff EC; Fang H; Wanders D; Judd RL
    Metabolism; 2016 Feb; 65(2):102-13. PubMed ID: 26773933
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Molecular modeling aided design of nicotinic acid receptor GPR109A agonists.
    Deng Q; Frie JL; Marley DM; Beresis RT; Ren N; Cai TQ; Taggart AK; Cheng K; Carballo-Jane E; Wang J; Tong X; Waters MG; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2008 Sep; 18(18):4963-7. PubMed ID: 18760600
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Nicotinic acid: recent developments.
    Kamanna VS; Vo A; Kashyap ML
    Curr Opin Cardiol; 2008 Jul; 23(4):393-8. PubMed ID: 18520725
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.
    Tang H; Lu JY; Zheng X; Yang Y; Reagan JD
    Biochem Biophys Res Commun; 2008 Oct; 375(4):562-5. PubMed ID: 18722346
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.
    Liu C; Wu J; Zhu J; Kuei C; Yu J; Shelton J; Sutton SW; Li X; Yun SJ; Mirzadegan T; Mazur C; Kamme F; Lovenberg TW
    J Biol Chem; 2009 Jan; 284(5):2811-2822. PubMed ID: 19047060
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.