141 related articles for article (PubMed ID: 21908190)
21. Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases.
Pan W; Liu H; Xu YJ; Chen X; Kim KH; Milligan DL; Columbus J; Hadari YR; Kussie P; Wong WC; Labelle M
Bioorg Med Chem Lett; 2005 Dec; 15(24):5474-7. PubMed ID: 16198560
[TBL] [Abstract][Full Text] [Related]
22. Triazolo compounds useful as diacylglycerol acyltransferase1 inhibitor - WO2009126624.
Matsuda D; Tomoda H
Expert Opin Ther Pat; 2010 Aug; 20(8):1097-102. PubMed ID: 20509774
[TBL] [Abstract][Full Text] [Related]
23. Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitors.
Liu Y; Fang J; Cai H; Xiao F; Ding K; Hu Y
Bioorg Med Chem; 2012 Sep; 20(18):5473-82. PubMed ID: 22898255
[TBL] [Abstract][Full Text] [Related]
24. Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1.
Mougenot P; Namane C; Fett E; Camy F; Dadji-Faïhun R; Langot G; Monseau C; Onofri B; Pacquet F; Pascal C; Crespin O; Ben-Hassine M; Ragot JL; Van-Pham T; Philippo C; Chatelain-Egger F; Péron P; Le Bail JC; Guillot E; Chamiot-Clerc P; Chabanaud MA; Pruniaux MP; Schmidt F; Venier O; Nicolaï E; Viviani F
Bioorg Med Chem Lett; 2012 Apr; 22(7):2497-502. PubMed ID: 22405833
[TBL] [Abstract][Full Text] [Related]
25. Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-Raf(V600E) kinase with favorable physicochemical and pharmacokinetic properties.
Ren L; Laird ER; Buckmelter AJ; Dinkel V; Gloor SL; Grina J; Newhouse B; Rasor K; Hastings G; Gradl SN; Rudolph J
Bioorg Med Chem Lett; 2012 Jan; 22(2):1165-8. PubMed ID: 22196124
[TBL] [Abstract][Full Text] [Related]
26. Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans.
Maciejewski BS; LaPerle JL; Chen D; Ghosh A; Zavadoski WJ; McDonald TS; Manion TB; Mather D; Patterson TA; Hanna M; Watkins S; Gibbs EM; Calle RA; Steppan CM
Am J Physiol Gastrointest Liver Physiol; 2013 Jun; 304(11):G958-69. PubMed ID: 23558010
[TBL] [Abstract][Full Text] [Related]
27. Novel acyl coenzyme A: diacylglycerol acyltransferase 1 inhibitors-synthesis and biological activities of N-(substituted heteroaryl)-4-(substituted phenyl)-4-oxobutanamides.
Nakada Y; Ogino M; Asano K; Aoki K; Miki H; Yamamoto T; Kato K; Masago M; Tamura N; Shimada M
Chem Pharm Bull (Tokyo); 2010 May; 58(5):673-9. PubMed ID: 20460795
[TBL] [Abstract][Full Text] [Related]
28. Discovery of a low-systemic-exposure DGAT-1 inhibitor with a picolinoylpyrrolidine-2-carboxylic acid moiety.
Yan J; Wang G; Dang X; Guo B; Chen W; Wang T; Zeng L; Wang H; Hu Y
Bioorg Med Chem; 2017 Sep; 25(17):4701-4714. PubMed ID: 28739155
[TBL] [Abstract][Full Text] [Related]
29. Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2.
Choi HS; Wang Z; Richmond W; He X; Yang K; Jiang T; Karanewsky D; Gu XJ; Zhou V; Liu Y; Che J; Lee CC; Caldwell J; Kanazawa T; Umemura I; Matsuura N; Ohmori O; Honda T; Gray N; He Y
Bioorg Med Chem Lett; 2006 May; 16(10):2689-92. PubMed ID: 16524731
[TBL] [Abstract][Full Text] [Related]
30. Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors.
Imbriglio JE; Shen DM; Liang R; Marby K; You M; Youm HW; Feng Z; London C; Xiong Y; Tata J; Verras A; Garcia-Calvo M; Song X; Addona GH; McLaren DG; He T; Murphy B; Metzger DE; Salituro G; Deckman D; Chen Q; Jin X; Stout SJ; Wang SP; Wilsie L; Palyha O; Han S; Hubbard BK; Previs SF; Pinto S; Taggart A
J Med Chem; 2015 Dec; 58(23):9345-53. PubMed ID: 26561979
[TBL] [Abstract][Full Text] [Related]
31. Aphadilactones A-D, four diterpenoid dimers with DGAT inhibitory and antimalarial activities from a Meliaceae plant.
Liu J; He XF; Wang GH; Merino EF; Yang SP; Zhu RX; Gan LS; Zhang H; Cassera MB; Wang HY; Kingston DG; Yue JM
J Org Chem; 2014 Jan; 79(2):599-607. PubMed ID: 24344740
[TBL] [Abstract][Full Text] [Related]
32. Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.
Yun W; Ahmad M; Chen Y; Gillespie P; Conde-Knape K; Kazmer S; Li S; Qian Y; Taub R; Wertheimer SJ; Whittard T; Bolin D
Bioorg Med Chem Lett; 2011 Dec; 21(23):7205-9. PubMed ID: 22001092
[TBL] [Abstract][Full Text] [Related]
33. Novel acyl coenzyme A (CoA): diacylglycerol acyltransferase-1 inhibitors: synthesis and biological activities of diacylethylenediamine derivatives.
Nakada Y; Aicher TD; Le Huerou Y; Turner T; Pratt SA; Gonzales SS; Boyd SA; Miki H; Yamamoto T; Yamaguchi H; Kato K; Kitamura S
Bioorg Med Chem; 2010 Apr; 18(7):2785-95. PubMed ID: 20207151
[TBL] [Abstract][Full Text] [Related]
34. Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors.
Lou J; Yang X; Rao Z; Qi W; Li J; Wang H; Li Y; Li J; Wang Z; Hu X; Liu P; Hong X
Eur J Med Chem; 2014 Aug; 83():466-73. PubMed ID: 24992074
[TBL] [Abstract][Full Text] [Related]
35. 3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: design and development to a highly selective lead.
Soth M; Abbot S; Abubakari A; Arora N; Arzeno H; Billedeau R; Dewdney N; Durkin K; Frauchiger S; Ghate M; Goldstein DM; Hill RJ; Kuglstatter A; Li F; Loe B; McCaleb K; McIntosh J; Papp E; Park J; Stahl M; Sung ML; Suttman R; Swinney DC; Weller P; Wong B; Zecic H; Gabriel T
Bioorg Med Chem Lett; 2011 Jun; 21(11):3452-6. PubMed ID: 21515047
[TBL] [Abstract][Full Text] [Related]
36. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.
Traxler P; Bold G; Frei J; Lang M; Lydon N; Mett H; Buchdunger E; Meyer T; Mueller M; Furet P
J Med Chem; 1997 Oct; 40(22):3601-16. PubMed ID: 9357527
[TBL] [Abstract][Full Text] [Related]
37. Sesquiterpenoids isolated from the flower buds of Tussilago farfara L. inhibit diacylglycerol acyltransferase.
Park HR; Yoo MY; Seo JH; Kim IS; Kim NY; Kang JY; Cui L; Lee CS; Lee CH; Lee HS
J Agric Food Chem; 2008 Nov; 56(22):10493-7. PubMed ID: 18937486
[TBL] [Abstract][Full Text] [Related]
38. Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors.
Perner RJ; Lee CH; Jiang M; Gu YG; Didomenico S; Bayburt EK; Alexander KM; Kohlhaas KL; Jarvis MF; Kowaluk EL; Bhagwat SS
Bioorg Med Chem Lett; 2005 Jun; 15(11):2803-7. PubMed ID: 15911258
[TBL] [Abstract][Full Text] [Related]
39. Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC).
Yu Y; Wu Z; Shi ZC; He S; Lai Z; Cernak TA; Vachal P; Liu M; Liu J; Hong Q; Jian T; Guiadeen D; Krikorian A; Sperbeck DM; Verras A; Sonatore LM; Murphy BA; Wiltsie J; Chung CC; Gorski JN; Liu J; Xiao J; Wolff M; Tong SX; Madeira M; Karanam BV; Shen DM; Balkovec JM; De Vita RJ; Pinto S; Nargund RP
Bioorg Med Chem Lett; 2019 Jun; 29(11):1380-1385. PubMed ID: 30952592
[TBL] [Abstract][Full Text] [Related]
40. Regulation of triglyceride metabolism. I. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT".
Turkish A; Sturley SL
Am J Physiol Gastrointest Liver Physiol; 2007 Apr; 292(4):G953-7. PubMed ID: 17095752
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
