BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 21908190)

  • 41. Diacylglycerol acyltransferase-inhibitory compounds from Erythrina senegalensis.
    Oh WK; Lee C; Seo JH; Chung MY; Cui L; Fomum ZT; Kang JS; Lee HS
    Arch Pharm Res; 2009 Jan; 32(1):43-7. PubMed ID: 19183875
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors.
    Schirok H; Kast R; Figueroa-Pérez S; Bennabi S; Gnoth MJ; Feurer A; Heckroth H; Thutewohl M; Paulsen H; Knorr A; Hütter J; Lobell M; Münter K; Geiss V; Ehmke H; Lang D; Radtke M; Mittendorf J; Stasch JP
    ChemMedChem; 2008 Dec; 3(12):1893-904. PubMed ID: 18973168
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Convergent synthesis and cruzain inhibitory activity of novel 2-(N'-benzylidenehydrazino)-4-trifluoromethyl-pyrimidines.
    Zanatta N; Amaral SS; Dos Santos JM; de Mello DL; Fernandes Lda S; Bonacorso HG; Martins MA; Andricopulo AD; Borchhardt DM
    Bioorg Med Chem; 2008 Dec; 16(24):10236-43. PubMed ID: 18996017
    [TBL] [Abstract][Full Text] [Related]  

  • 44. 7-Phenyl-pyrido[2,3-d]pyrimidine-2,4-diamines: novel and highly selective protein tyrosine phosphatase 1B inhibitors.
    Cheung AW; Banner B; Bose J; Kim K; Li S; Marcopulos N; Orzechowski L; Sergi JA; Thakkar KC; Wang BB; Yun W; Zwingelstein C; Berthel S; Olivier AR
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7518-22. PubMed ID: 23122867
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Synthesis and biological activity of 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine CDK inhibitors.
    Wang S; Wood G; Meades C; Griffiths G; Midgley C; McNae I; McInnes C; Anderson S; Jackson W; Mezna M; Yuill R; Walkinshaw M; Fischer PM
    Bioorg Med Chem Lett; 2004 Aug; 14(16):4237-40. PubMed ID: 15261277
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Inhibitory activity of diacylglycerol acyltransferase by glabrol isolated from the roots of licorice.
    Choi JH; Choi JN; Lee SY; Lee SJ; Kim K; Kim YK
    Arch Pharm Res; 2010 Feb; 33(2):237-42. PubMed ID: 20195824
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Design, synthesis and biological study of novel pyrido[2,3-d]pyrimidine as anti-proliferative CDK2 inhibitors.
    Ibrahim DA; Ismail NS
    Eur J Med Chem; 2011 Dec; 46(12):5825-32. PubMed ID: 22000924
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines: identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors.
    Boschelli DH; Wu Z; Klutchko SR; Showalter HD; Hamby JM; Lu GH; Major TC; Dahring TK; Batley B; Panek RL; Keiser J; Hartl BG; Kraker AJ; Klohs WD; Roberts BJ; Patmore S; Elliott WL; Steinkampf R; Bradford LA; Hallak H; Doherty AM
    J Med Chem; 1998 Oct; 41(22):4365-77. PubMed ID: 9784112
    [TBL] [Abstract][Full Text] [Related]  

  • 49. 4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.
    Maeda Y; Nakano M; Sato H; Miyazaki Y; Schweiker SL; Smith JL; Truesdale AT
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3907-11. PubMed ID: 15225695
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Discovery of pyrrolopyridazines as novel DGAT1 inhibitors.
    Fox BM; Iio K; Li K; Choi R; Inaba T; Jackson S; Sagawa S; Shan B; Tanaka M; Yoshida A; Kayser F
    Bioorg Med Chem Lett; 2010 Oct; 20(20):6030-3. PubMed ID: 20833038
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Current status of the research and development of diacylglycerol O-acyltransferase 1 (DGAT1) inhibitors.
    DeVita RJ; Pinto S
    J Med Chem; 2013 Dec; 56(24):9820-5. PubMed ID: 23919406
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents.
    Fox BM; Sugimoto K; Iio K; Yoshida A; Zhang JK; Li K; Hao X; Labelle M; Smith ML; Rubenstein SM; Ye G; McMinn D; Jackson S; Choi R; Shan B; Ma J; Miao S; Matsui T; Ogawa N; Suzuki M; Kobayashi A; Ozeki H; Okuma C; Ishii Y; Tomimoto D; Furakawa N; Tanaka M; Matsushita M; Takahashi M; Inaba T; Sagawa S; Kayser F
    J Med Chem; 2014 Apr; 57(8):3464-83. PubMed ID: 24670009
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.
    Pagire SH; Pagire HS; Lee GB; Han SJ; Kwak HJ; Kim JY; Kim KY; Rhee SD; Ryu JI; Song JS; Bae MA; Park MJ; Kim D; Lee DH; Ahn JH
    Eur J Med Chem; 2015 Aug; 101():716-35. PubMed ID: 26218650
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Model-based pharmacokinetic and pharmacodynamic analysis for acute effects of a small molecule inhibitor of diacylglycerol acyltransferase-1 in the TallyHo/JngJ polygenic mouse.
    Chae YJ; Song JS; Ahn JH; Bae MA; Lee KR
    Xenobiotica; 2019 Jul; 49(7):823-832. PubMed ID: 29972081
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Patent landscape for discovery of promising acyltransferase DGAT and MGAT inhibitors.
    Zambre VP; Khamkar SM; Gavhane DD; Khedkar SC; Chavan MR; Pandey MM; Sanap SB; Patil RB; Sawant SD
    Expert Opin Ther Pat; 2020 Nov; 30(11):873-896. PubMed ID: 32878484
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Synthesis and evaluation of a new series of substituted acyl(thio)urea and thiadiazolo [2,3-a] pyrimidine derivatives as potent inhibitors of influenza virus neuraminidase.
    Sun C; Zhang X; Huang H; Zhou P
    Bioorg Med Chem; 2006 Dec; 14(24):8574-81. PubMed ID: 16979342
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Novel pyrimidines as acid pump antagonists (APAs).
    Yoon YA; Park CS; Cha MH; Choi H; Sim JY; Kim JG
    Bioorg Med Chem Lett; 2010 Oct; 20(19):5735-8. PubMed ID: 20810280
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Expression of two human acyl-CoA:diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes.
    Inokoshi J; Kawamoto K; Takagi Y; Matsuhama M; Omura S; Tomoda H
    J Antibiot (Tokyo); 2009 Jan; 62(1):51-4. PubMed ID: 19132064
    [TBL] [Abstract][Full Text] [Related]  

  • 59. A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity.
    Yamamoto T; Yamaguchi H; Miki H; Kitamura S; Nakada Y; Aicher TD; Pratt SA; Kato K
    Eur J Pharmacol; 2011 Jan; 650(2-3):663-72. PubMed ID: 21034741
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Synthesis and structure-activity relationship of tricyclic carboxylic acids as novel anti-histamines.
    Kubota K; Kurebayashi H; Miyachi H; Tobe M; Onishi M; Isobe Y
    Bioorg Med Chem; 2011 May; 19(9):3005-21. PubMed ID: 21470866
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.