BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 21910480)

  • 1. Identification, tissue distribution, and molecular modeling of novel human isoforms of the key enzyme in sialic acid synthesis, UDP-GlcNAc 2-epimerase/ManNAc kinase.
    Yardeni T; Choekyi T; Jacobs K; Ciccone C; Patzel K; Anikster Y; Gahl WA; Kurochkina N; Huizing M
    Biochemistry; 2011 Oct; 50(41):8914-25. PubMed ID: 21910480
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Murine isoforms of UDP-GlcNAc 2-epimerase/ManNAc kinase: Secondary structures, expression profiles, and response to ManNAc therapy.
    Yardeni T; Jacobs K; Niethamer TK; Ciccone C; Anikster Y; Kurochkina N; Gahl WA; Huizing M
    Glycoconj J; 2013 Aug; 30(6):609-18. PubMed ID: 23266873
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lec3 Chinese hamster ovary mutants lack UDP-N-acetylglucosamine 2-epimerase activity because of mutations in the epimerase domain of the Gne gene.
    Hong Y; Stanley P
    J Biol Chem; 2003 Dec; 278(52):53045-54. PubMed ID: 14561743
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular modeling of the bifunctional enzyme UDP-GlcNAc 2-epimerase/ManNAc kinase and predictions of structural effects of mutations associated with HIBM and sialuria.
    Kurochkina N; Yardeni T; Huizing M
    Glycobiology; 2010 Mar; 20(3):322-37. PubMed ID: 19917666
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Molecular cloning and functional expression of UDP-N-acetyl-glucosamine 2-epimerase/N-acetylmannosamine kinase.
    Stäsche R; Hinderlich S; Weise C; Effertz K; Lucka L; Moormann P; Reutter W
    J Biol Chem; 1997 Sep; 272(39):24319-24. PubMed ID: 9305888
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.
    Reinke SO; Lehmer G; Hinderlich S; Reutter W
    Biol Chem; 2009 Jul; 390(7):591-9. PubMed ID: 19426133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase from
    Ko TP; Lai SJ; Hsieh TJ; Yang CS; Chen Y
    J Biol Chem; 2018 Jun; 293(26):10119-10127. PubMed ID: 29764940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis.
    Chen SC; Huang CH; Lai SJ; Yang CS; Hsiao TH; Lin CH; Fu PK; Ko TP; Chen Y
    Sci Rep; 2016 Mar; 6():23274. PubMed ID: 26980148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Purification and characterization of GlcNAc-6-P 2-epimerase from Escherichia coli K92.
    Ferrero MA; Martínez-Blanco H; Lopez-Velasco FF; Ezquerro-Sáenz C; Navasa N; Lozano S; Rodríguez-Aparicio LB
    Acta Biochim Pol; 2007; 54(2):387-99. PubMed ID: 17565386
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases.
    Campbell RE; Mosimann SC; Tanner ME; Strynadka NC
    Biochemistry; 2000 Dec; 39(49):14993-5001. PubMed ID: 11106477
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni.
    Bernatchez S; Szymanski CM; Ishiyama N; Li J; Jarrell HC; Lau PC; Berghuis AM; Young NM; Wakarchuk WW
    J Biol Chem; 2005 Feb; 280(6):4792-802. PubMed ID: 15509570
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biochemical characterization of UDP-GlcNAc/Glc 4-epimerase from Escherichia coli O86:B7.
    Guo H; Li L; Wang PG
    Biochemistry; 2006 Nov; 45(46):13760-8. PubMed ID: 17105195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles for UDP-GlcNAc 2-epimerase/ManNAc 6-kinase outside of sialic acid biosynthesis: modulation of sialyltransferase and BiP expression, GM3 and GD3 biosynthesis, proliferation, and apoptosis, and ERK1/2 phosphorylation.
    Wang Z; Sun Z; Li AV; Yarema KJ
    J Biol Chem; 2006 Sep; 281(37):27016-28. PubMed ID: 16847058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenetically mediated loss of UDP-GlcNAc 2-epimerase/ManNAc kinase expression in hyposialylated cell lines.
    Oetke C; Hinderlich S; Reutter W; Pawlita M
    Biochem Biophys Res Commun; 2003 Sep; 308(4):892-8. PubMed ID: 12927803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Purification and characterization of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.
    Hinderlich S; Stäsche R; Zeitler R; Reutter W
    J Biol Chem; 1997 Sep; 272(39):24313-8. PubMed ID: 9305887
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective loss of either the epimerase or kinase activity of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase due to site-directed mutagenesis based on sequence alignments.
    Effertz K; Hinderlich S; Reutter W
    J Biol Chem; 1999 Oct; 274(40):28771-8. PubMed ID: 10497249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical characterization of human and murine isoforms of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE).
    Reinke SO; Eidenschink C; Jay CM; Hinderlich S
    Glycoconj J; 2009 May; 26(4):415-22. PubMed ID: 18815882
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism.
    Luchansky SJ; Yarema KJ; Takahashi S; Bertozzi CR
    J Biol Chem; 2003 Mar; 278(10):8035-42. PubMed ID: 12499362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterizing non-hydrolyzing Neisseria meningitidis serogroup A UDP-N-acetylglucosamine (UDP-GlcNAc) 2-epimerase using UDP-N-acetylmannosamine (UDP-ManNAc) and derivatives.
    Zhang L; Muthana MM; Yu H; McArthur JB; Qu J; Chen X
    Carbohydr Res; 2016 Jan; 419():18-28. PubMed ID: 26598987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Influence of UDP-GlcNAc 2-epimerase/ManNAc kinase mutant proteins on hereditary inclusion body myopathy.
    Penner J; Mantey LR; Elgavish S; Ghaderi D; Cirak S; Berger M; Krause S; Lucka L; Voit T; Mitrani-Rosenbaum S; Hinderlich S
    Biochemistry; 2006 Mar; 45(9):2968-77. PubMed ID: 16503651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.