BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 21911456)

  • 1. 2-deoxyglucose induces Noxa-dependent apoptosis in alveolar rhabdomyosarcoma.
    Ramírez-Peinado S; Alcázar-Limones F; Lagares-Tena L; El Mjiyad N; Caro-Maldonado A; Tirado OM; Muñoz-Pinedo C
    Cancer Res; 2011 Nov; 71(21):6796-806. PubMed ID: 21911456
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATF4 mediates necrosis induced by glucose deprivation and apoptosis induced by 2-deoxyglucose in the same cells.
    León-Annicchiarico CL; Ramírez-Peinado S; Domínguez-Villanueva D; Gonsberg A; Lampidis TJ; Muñoz-Pinedo C
    FEBS J; 2015 Sep; 282(18):3647-58. PubMed ID: 26172539
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.
    Coloff JL; Macintyre AN; Nichols AG; Liu T; Gallo CA; Plas DR; Rathmell JC
    Cancer Res; 2011 Aug; 71(15):5204-13. PubMed ID: 21670080
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P; Wuillème-Toumi S; Ménoret E; Trichet V; Robillard N; Philippe M; Bataille R; Amiot M
    Cancer Res; 2007 Jun; 67(11):5418-24. PubMed ID: 17545623
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcoma.
    Jothi M; Mal M; Keller C; Mal AK
    Mol Cancer Ther; 2013 Dec; 12(12):2663-74. PubMed ID: 24107448
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.
    Gómez-Benito M; Marzo I; Anel A; Naval J
    Mol Pharmacol; 2005 Jun; 67(6):1991-8. PubMed ID: 15738311
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress.
    Liu H; Kurtoglu M; León-Annicchiarico CL; Munoz-Pinedo C; Barredo J; Leclerc G; Merchan J; Liu X; Lampidis TJ
    Oncotarget; 2016 Jun; 7(24):36461-36473. PubMed ID: 27183907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PAX3-FOXO1 induces up-regulation of Noxa sensitizing alveolar rhabdomyosarcoma cells to apoptosis.
    Marshall AD; Picchione F; Geltink RI; Grosveld GC
    Neoplasia; 2013 Jul; 15(7):738-48. PubMed ID: 23814486
    [TBL] [Abstract][Full Text] [Related]  

  • 10. By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737.
    Tailler M; Lindqvist LM; Gibson L; Adams JM
    Cell Death Differ; 2019 Sep; 26(9):1766-1781. PubMed ID: 30538285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma.
    Hugle M; Fulda S
    Cancer Lett; 2015 Apr; 360(1):1-9. PubMed ID: 25637161
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.
    Bois PR; Izeradjene K; Houghton PJ; Cleveland JL; Houghton JA; Grosveld GC
    J Cell Biol; 2005 Sep; 170(6):903-12. PubMed ID: 16157701
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.
    Nakajima W; Tanaka N
    J Nippon Med Sch; 2007 Apr; 74(2):148-57. PubMed ID: 17507791
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Akt potentiates 2-DG-induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia.
    DeSalvo J; Kuznetsov JN; Du J; Leclerc GM; Leclerc GJ; Lampidis TJ; Barredo JC
    Mol Cancer Res; 2012 Jul; 10(7):969-78. PubMed ID: 22692960
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couple ER stress to mitochondrial apoptosis.
    Gomez-Bougie P; Halliez M; Moreau P; Pellat-Deceunynck C; Amiot M
    Cancer Lett; 2016 Dec; 383(2):204-211. PubMed ID: 27697610
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells.
    Inoue S; Walewska R; Dyer MJ; Cohen GM
    Leukemia; 2008 Apr; 22(4):819-25. PubMed ID: 18239621
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional linkage between NOXA and Bim in mitochondrial apoptotic events.
    Han J; Goldstein LA; Hou W; Rabinowich H
    J Biol Chem; 2007 Jun; 282(22):16223-31. PubMed ID: 17374615
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.
    Taniai M; Grambihler A; Higuchi H; Werneburg N; Bronk SF; Farrugia DJ; Kaufmann SH; Gores GJ
    Cancer Res; 2004 May; 64(10):3517-24. PubMed ID: 15150106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.
    Descamps G; Gomez-Bougie P; Tamburini J; Green A; Bouscary D; Maïga S; Moreau P; Le Gouill S; Pellat-Deceunynck C; Amiot M
    Br J Cancer; 2012 May; 106(10):1660-7. PubMed ID: 22510748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.