86 related articles for article (PubMed ID: 21912861)
1. Effect of double mutations K214/A-E215/Q of FRATide on GSK3β: insights from molecular dynamics simulation and normal mode analysis.
Lu SY; Jiang YJ; Zou JW; Wu TX
Amino Acids; 2012 Jul; 43(1):267-77. PubMed ID: 21912861
[TBL] [Abstract][Full Text] [Related]
2. Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis.
Lu S; Jiang Y; Lv J; Zou J; Wu T
Biopolymers; 2011 Oct; 95(10):669-81. PubMed ID: 21442609
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex.
Dajani R; Fraser E; Roe SM; Yeo M; Good VM; Thompson V; Dale TC; Pearl LH
EMBO J; 2003 Feb; 22(3):494-501. PubMed ID: 12554650
[TBL] [Abstract][Full Text] [Related]
4. Structural basis for the complete loss of GSK3beta catalytic activity due to R96 mutation investigated by molecular dynamics study.
Zhang N; Jiang Y; Zou J; Yu Q; Zhao W
Proteins; 2009 May; 75(3):671-81. PubMed ID: 19003984
[TBL] [Abstract][Full Text] [Related]
5. Molecular modeling and molecular dynamics simulation studies of the GSK3β/ATP/substrate complex: understanding the unique P+4 primed phosphorylation specificity for GSK3β substrates.
Lu SY; Jiang YJ; Zou JW; Wu TX
J Chem Inf Model; 2011 May; 51(5):1025-36. PubMed ID: 21495724
[TBL] [Abstract][Full Text] [Related]
6. Unraveling the role of Arg4 and Arg6 in the auto-inhibition mechanism of GSK3β from molecular dynamics simulation.
Mou L; Li M; Lu SY; Li S; Shen Q; Zhang J; Li C; Lu X
Chem Biol Drug Des; 2014 Jun; 83(6):721-30. PubMed ID: 24444018
[TBL] [Abstract][Full Text] [Related]
7. Insights into unbinding mechanisms upon two mutations investigated by molecular dynamics study of GSK3beta-axin complex: role of packing hydrophobic residues.
Zhang N; Jiang Y; Zou J; Zhuang S; Jin H; Yu Q
Proteins; 2007 Jun; 67(4):941-9. PubMed ID: 17380482
[TBL] [Abstract][Full Text] [Related]
8. Prediction of the binding mode between GSK3β and a peptide derived from GSKIP using molecular dynamics simulation.
Tang XN; Lo CW; Chuang YC; Chen CT; Sun YC; Hong YR; Yang CN
Biopolymers; 2011 Jul; 95(7):461-71. PubMed ID: 21328310
[TBL] [Abstract][Full Text] [Related]
9. How calcium inhibits the magnesium-dependent kinase gsk3β: a molecular simulation study.
Lu SY; Huang ZM; Huang WK; Liu XY; Chen YY; Shi T; Zhang J
Proteins; 2013 May; 81(5):740-53. PubMed ID: 23184735
[TBL] [Abstract][Full Text] [Related]
10. Microsecond molecular dynamics simulations and dynamic network analysis provide understanding of the allosteric inactivation of GSK3β induced by the L343R mutation.
Li J; Fu Q; Liang Y; Cheng B; Li X
J Mol Model; 2019 Apr; 25(5):111. PubMed ID: 30949773
[TBL] [Abstract][Full Text] [Related]
11. Regulation of protein kinases in insulin, growth factor and Wnt signalling.
Pearl LH; Barford D
Curr Opin Struct Biol; 2002 Dec; 12(6):761-7. PubMed ID: 12504681
[TBL] [Abstract][Full Text] [Related]
12. GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta.
Chou HY; Howng SL; Cheng TS; Hsiao YL; Lieu AS; Loh JK; Hwang SL; Lin CC; Hsu CM; Wang C; Lee CI; Lu PJ; Chou CK; Huang CY; Hong YR
Biochemistry; 2006 Sep; 45(38):11379-89. PubMed ID: 16981698
[TBL] [Abstract][Full Text] [Related]
13. Homology modeling and molecular dynamics study of GSK3/SHAGGY-like kinase.
Xiao JF; Li ZS; Sun M; Zhang Y; Sun CC
Comput Biol Chem; 2004 Jul; 28(3):179-88. PubMed ID: 15261148
[TBL] [Abstract][Full Text] [Related]
14. Semaphorin3A-induced axonal transport mediated through phosphorylation of Axin-1 by GSK3β.
Hida T; Nakamura F; Usui H; Takeuchi K; Yamashita N; Goshima Y
Brain Res; 2015 Feb; 1598():46-56. PubMed ID: 25528666
[TBL] [Abstract][Full Text] [Related]
15. The structural basis of the autoinhibition mechanism of glycogen synthase kinase 3β (GSK3β): molecular modeling and molecular dynamics simulation studies.
Mou L; Dou W; Meng G; Sun K; Chen X
J Biomol Struct Dyn; 2020 Apr; 38(6):1741-1750. PubMed ID: 31057052
[TBL] [Abstract][Full Text] [Related]
16. Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells.
Ghosh JC; Altieri DC
Clin Cancer Res; 2005 Jun; 11(12):4580-8. PubMed ID: 15958644
[TBL] [Abstract][Full Text] [Related]
17. A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression.
Jho Eh; Lomvardas S; Costantini F
Biochem Biophys Res Commun; 1999 Dec; 266(1):28-35. PubMed ID: 10581160
[TBL] [Abstract][Full Text] [Related]
18. Structure of GSK3beta reveals a primed phosphorylation mechanism.
ter Haar E; Coll JT; Austen DA; Hsiao HM; Swenson L; Jain J
Nat Struct Biol; 2001 Jul; 8(7):593-6. PubMed ID: 11427888
[TBL] [Abstract][Full Text] [Related]
19. Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.
Sinha D; Wang Z; Ruchalski KL; Levine JS; Krishnan S; Lieberthal W; Schwartz JH; Borkan SC
Am J Physiol Renal Physiol; 2005 Apr; 288(4):F703-13. PubMed ID: 15572521
[TBL] [Abstract][Full Text] [Related]
20. Dissection of the difference between the group I metal ions in inhibiting GSK3β: a computational study.
Lu SY; Jiang YJ; Zou JW; Wu TX
Phys Chem Chem Phys; 2011 Apr; 13(15):7014-23. PubMed ID: 21409189
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
