396 related articles for article (PubMed ID: 21914785)
1. PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis.
Bhalla K; Hwang BJ; Dewi RE; Ou L; Twaddel W; Fang HB; Vafai SB; Vazquez F; Puigserver P; Boros L; Girnun GD
Cancer Res; 2011 Nov; 71(21):6888-98. PubMed ID: 21914785
[TBL] [Abstract][Full Text] [Related]
2. CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways.
Li J; Huang Q; Long X; Zhang J; Huang X; Aa J; Yang H; Chen Z; Xing J
J Hepatol; 2015 Dec; 63(6):1378-89. PubMed ID: 26282231
[TBL] [Abstract][Full Text] [Related]
3. PPARγ Coactivator-1α Suppresses Metastasis of Hepatocellular Carcinoma by Inhibiting Warburg Effect by PPARγ-Dependent WNT/β-Catenin/Pyruvate Dehydrogenase Kinase Isozyme 1 Axis.
Zuo Q; He J; Zhang S; Wang H; Jin G; Jin H; Cheng Z; Tao X; Yu C; Li B; Yang C; Wang S; Lv Y; Zhao F; Yao M; Cong W; Wang C; Qin W
Hepatology; 2021 Feb; 73(2):644-660. PubMed ID: 32298475
[TBL] [Abstract][Full Text] [Related]
4. USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma.
Ning Z; Guo X; Liu X; Lu C; Wang A; Wang X; Wang W; Chen H; Qin W; Liu X; Zhou L; Ma C; Du J; Lin Z; Luo H; Otkur W; Qi H; Chen D; Xia T; Liu J; Tan G; Xu G; Piao HL
Nat Commun; 2022 Apr; 13(1):2187. PubMed ID: 35449157
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nelson ME; Lahiri S; Chow JD; Byrne FL; Hargett SR; Breen DS; Olzomer EM; Wu LE; Cooney GJ; Turner N; James DE; Slack-Davis JK; Lackner C; Caldwell SH; Hoehn KL
Nat Commun; 2017 Mar; 8():14689. PubMed ID: 28290443
[TBL] [Abstract][Full Text] [Related]
6. Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
Wang MD; Wu H; Fu GB; Zhang HL; Zhou X; Tang L; Dong LW; Qin CJ; Huang S; Zhao LH; Zeng M; Wu MC; Yan HX; Wang HY
Hepatology; 2016 Apr; 63(4):1272-86. PubMed ID: 26698170
[TBL] [Abstract][Full Text] [Related]
7. ATP-Citrate Lyase Epigenetically Potentiates Oxidative Phosphorylation to Promote Melanoma Growth and Adaptive Resistance to MAPK Inhibition.
Guo W; Ma J; Yang Y; Guo S; Zhang W; Zhao T; Yi X; Wang H; Wang S; Liu Y; Dai W; Chen X; Shi Q; Wang G; Gao T; Li C
Clin Cancer Res; 2020 Jun; 26(11):2725-2739. PubMed ID: 32034077
[TBL] [Abstract][Full Text] [Related]
8. Hepatic peroxisome proliferator-activated receptor γ coactivator 1β drives mitochondrial and anabolic signatures that contribute to hepatocellular carcinoma progression in mice.
Piccinin E; Peres C; Bellafante E; Ducheix S; Pinto C; Villani G; Moschetta A
Hepatology; 2018 Mar; 67(3):884-898. PubMed ID: 28857232
[TBL] [Abstract][Full Text] [Related]
9. P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice.
Dusabimana T; Park EJ; Je J; Jeong K; Yun SP; Kim HJ; Kim H; Park SW
Int J Mol Sci; 2021 May; 22(11):. PubMed ID: 34073834
[TBL] [Abstract][Full Text] [Related]
10. Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.
Abu-Elheiga L; Wu H; Gu Z; Bressler R; Wakil SJ
J Biol Chem; 2012 Apr; 287(15):12578-88. PubMed ID: 22362781
[TBL] [Abstract][Full Text] [Related]
11. Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.
Calvisi DF; Wang C; Ho C; Ladu S; Lee SA; Mattu S; Destefanis G; Delogu S; Zimmermann A; Ericsson J; Brozzetti S; Staniscia T; Chen X; Dombrowski F; Evert M
Gastroenterology; 2011 Mar; 140(3):1071-83. PubMed ID: 21147110
[TBL] [Abstract][Full Text] [Related]
12. SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer.
Vellinga TT; Borovski T; de Boer VC; Fatrai S; van Schelven S; Trumpi K; Verheem A; Snoeren N; Emmink BL; Koster J; Rinkes IH; Kranenburg O
Clin Cancer Res; 2015 Jun; 21(12):2870-9. PubMed ID: 25779952
[TBL] [Abstract][Full Text] [Related]
13. Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Che L; Pilo MG; Cigliano A; Latte G; Simile MM; Ribback S; Dombrowski F; Evert M; Chen X; Calvisi DF
Cell Cycle; 2017 Mar; 16(6):499-507. PubMed ID: 28118080
[TBL] [Abstract][Full Text] [Related]
14. Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.
Li L; Che L; Tharp KM; Park HM; Pilo MG; Cao D; Cigliano A; Latte G; Xu Z; Ribback S; Dombrowski F; Evert M; Gores GJ; Stahl A; Calvisi DF; Chen X
Hepatology; 2016 Jun; 63(6):1900-13. PubMed ID: 26910791
[TBL] [Abstract][Full Text] [Related]
15. Fructose-1,6-Bisphosphate Aldolase B Depletion Promotes Hepatocellular Carcinogenesis Through Activating Insulin Receptor Signaling and Lipogenesis.
Liu G; Wang N; Zhang C; Li M; He X; Yin C; Tu Q; Shen X; Zhang L; Lv J; Wang Y; Jiang H; Chen S; Li N; Tao Y; Yin H
Hepatology; 2021 Dec; 74(6):3037-3055. PubMed ID: 34292642
[TBL] [Abstract][Full Text] [Related]
16. Regulating cardiac energy metabolism and bioenergetics by targeting the DNA damage repair protein BRCA1.
Singh KK; Shukla PC; Yanagawa B; Quan A; Lovren F; Pan Y; Wagg CS; Teoh H; Lopaschuk GD; Verma S
J Thorac Cardiovasc Surg; 2013 Sep; 146(3):702-9. PubMed ID: 23317938
[TBL] [Abstract][Full Text] [Related]
17. Deletion of the transcriptional coactivator PGC1α in skeletal muscles is associated with reduced expression of genes related to oxidative muscle function.
Hatazawa Y; Minami K; Yoshimura R; Onishi T; Manio MC; Inoue K; Sawada N; Suzuki O; Miura S; Kamei Y
Biochem Biophys Res Commun; 2016 Dec; 481(3-4):251-258. PubMed ID: 27816452
[TBL] [Abstract][Full Text] [Related]
18. Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity.
Crowe S; Turpin SM; Ke F; Kemp BE; Watt MJ
Endocrinology; 2008 May; 149(5):2546-56. PubMed ID: 18276754
[TBL] [Abstract][Full Text] [Related]
19. Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice.
Aharoni-Simon M; Hann-Obercyger M; Pen S; Madar Z; Tirosh O
Lab Invest; 2011 Jul; 91(7):1018-28. PubMed ID: 21464822
[TBL] [Abstract][Full Text] [Related]
20. HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress.
Wang MD; Wu H; Huang S; Zhang HL; Qin CJ; Zhao LH; Fu GB; Zhou X; Wang XM; Tang L; Wen W; Yang W; Tang SH; Cao D; Guo LN; Zeng M; Wu MC; Yan HX; Wang HY
Oncotarget; 2016 Feb; 7(6):6711-26. PubMed ID: 26744319
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
