300 related articles for article (PubMed ID: 21914810)
1. The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signaling.
Rapley J; Oshiro N; Ortiz-Vega S; Avruch J
J Biol Chem; 2011 Nov; 286(44):38043-38053. PubMed ID: 21914810
[TBL] [Abstract][Full Text] [Related]
2. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
[TBL] [Abstract][Full Text] [Related]
3. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex.
Fonseca BD; Smith EM; Lee VH; MacKintosh C; Proud CG
J Biol Chem; 2007 Aug; 282(34):24514-24. PubMed ID: 17604271
[TBL] [Abstract][Full Text] [Related]
4. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
Zhang L; Kimball SR; Jefferson LS; Shenberger JS
Free Radic Biol Med; 2009 Jun; 46(11):1500-9. PubMed ID: 19281842
[TBL] [Abstract][Full Text] [Related]
5. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
Mi W; Ye Q; Liu S; She QB
Oncotarget; 2015 Jun; 6(16):13962-77. PubMed ID: 25961827
[TBL] [Abstract][Full Text] [Related]
6. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
[TBL] [Abstract][Full Text] [Related]
7. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L; Harris TE; Roth RA; Lawrence JC
J Biol Chem; 2007 Jul; 282(27):20036-44. PubMed ID: 17510057
[TBL] [Abstract][Full Text] [Related]
8. Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
Wang L; Harris TE; Lawrence JC
J Biol Chem; 2008 Jun; 283(23):15619-27. PubMed ID: 18372248
[TBL] [Abstract][Full Text] [Related]
9. PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis.
Thedieck K; Polak P; Kim ML; Molle KD; Cohen A; Jenö P; Arrieumerlou C; Hall MN
PLoS One; 2007 Nov; 2(11):e1217. PubMed ID: 18030348
[TBL] [Abstract][Full Text] [Related]
10. Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.
Sato T; Nakashima A; Guo L; Tamanoi F
J Biol Chem; 2009 May; 284(19):12783-91. PubMed ID: 19299511
[TBL] [Abstract][Full Text] [Related]
11. Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction.
Hong-Brown LQ; Brown CR; Kazi AA; Huber DS; Pruznak AM; Lang CH
J Cell Biochem; 2010 Apr; 109(6):1172-84. PubMed ID: 20127721
[TBL] [Abstract][Full Text] [Related]
12. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
[TBL] [Abstract][Full Text] [Related]
13. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
Misra UK; Pizzo SV
PLoS One; 2012; 7(12):e51735. PubMed ID: 23272152
[TBL] [Abstract][Full Text] [Related]
14. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
[TBL] [Abstract][Full Text] [Related]
15. Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.
Chen L; Xu B; Liu L; Liu C; Luo Y; Chen X; Barzegar M; Chung J; Huang S
Oncotarget; 2015 Mar; 6(9):7136-50. PubMed ID: 25762619
[TBL] [Abstract][Full Text] [Related]
16. PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Sancak Y; Thoreen CC; Peterson TR; Lindquist RA; Kang SA; Spooner E; Carr SA; Sabatini DM
Mol Cell; 2007 Mar; 25(6):903-15. PubMed ID: 17386266
[TBL] [Abstract][Full Text] [Related]
17. Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
Liu L; Luo Y; Chen L; Shen T; Xu B; Chen W; Zhou H; Han X; Huang S
J Biol Chem; 2010 Dec; 285(49):38362-73. PubMed ID: 20937815
[TBL] [Abstract][Full Text] [Related]
18. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
[TBL] [Abstract][Full Text] [Related]
19. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
[TBL] [Abstract][Full Text] [Related]
20. Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition.
Dunlop EA; Dodd KM; Seymour LA; Tee AR
Cell Signal; 2009 Jul; 21(7):1073-84. PubMed ID: 19272448
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
