These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 21915392)

  • 1. Modifiers of mutant huntingtin aggregation: functional conservation of C. elegans-modifiers of polyglutamine aggregation.
    Teuling E; Bourgonje A; Veenje S; Thijssen K; de Boer J; van der Velde J; Swertz M; Nollen E
    PLoS Curr; 2011 Aug; 3():RRN1255. PubMed ID: 21915392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington's Disease Model.
    Titus SA; Southall N; Marugan J; Austin CP; Zheng W
    Curr Chem Genomics; 2012; 6():79-86. PubMed ID: 23346268
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analyzing modifiers of protein aggregation in C. elegans by native agarose gel electrophoresis.
    Holmberg M; Nollen EA
    Methods Mol Biol; 2013; 1017():193-9. PubMed ID: 23719917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?
    Schipper-Krom S; Juenemann K; Reits EA
    Biochem Res Int; 2012; 2012():837015. PubMed ID: 23050151
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation.
    Peters TW; Nelson CS; Gerencser AA; Dumas KJ; Tavshanjian B; Chang KC; Lithgow GJ; Hughes RE
    G3 (Bethesda); 2018 Nov; 8(11):3421-3431. PubMed ID: 30194090
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation.
    Doumanis J; Wada K; Kino Y; Moore AW; Nukina N
    PLoS One; 2009 Sep; 4(9):e7275. PubMed ID: 19789644
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation.
    Howard RA; Sharma P; Hajjar C; Caldwell KA; Caldwell GA; du Breuil R; Moore R; Boyd L
    BMC Cell Biol; 2007 Jul; 8():32. PubMed ID: 17663792
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model.
    Weiss KR; Kimura Y; Lee WC; Littleton JT
    Genetics; 2012 Feb; 190(2):581-600. PubMed ID: 22095086
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Poly(trehalose) Nanoparticles Prevent Amyloid Aggregation and Suppress Polyglutamine Aggregation in a Huntington's Disease Model Mouse.
    Debnath K; Pradhan N; Singh BK; Jana NR; Jana NR
    ACS Appl Mater Interfaces; 2017 Jul; 9(28):24126-24139. PubMed ID: 28632387
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biodegradable delivery system containing a peptide inhibitor of polyglutamine aggregation: a step toward therapeutic development in Huntington's disease.
    Joshi AS; Thakur AK
    J Pept Sci; 2014 Aug; 20(8):630-9. PubMed ID: 24788406
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila.
    Zhang S; Binari R; Zhou R; Perrimon N
    Genetics; 2010 Apr; 184(4):1165-79. PubMed ID: 20100940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.
    Lejeune FX; Mesrob L; Parmentier F; Bicep C; Vazquez-Manrique RP; Parker JA; Vert JP; Tourette C; Neri C
    BMC Genomics; 2012 Mar; 13():91. PubMed ID: 22413862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation.
    Wang J; Gines S; MacDonald ME; Gusella JF
    BMC Neurosci; 2005 Jan; 6():1. PubMed ID: 15649316
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.
    Bates EA; Victor M; Jones AK; Shi Y; Hart AC
    J Neurosci; 2006 Mar; 26(10):2830-8. PubMed ID: 16525063
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease model.
    Schulte J; Sepp KJ; Wu C; Hong P; Littleton JT
    PLoS One; 2011; 6(8):e23841. PubMed ID: 21909362
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies.
    Wright GEB; Black HF; Collins JA; Gall-Duncan T; Caron NS; Pearson CE; Hayden MR
    Lancet Neurol; 2020 Nov; 19(11):930-939. PubMed ID: 33098802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.
    Goswami A; Dikshit P; Mishra A; Mulherkar S; Nukina N; Jana NR
    Biochem Biophys Res Commun; 2006 Mar; 342(1):184-90. PubMed ID: 16472774
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease.
    Lecerf JM; Shirley TL; Zhu Q; Kazantsev A; Amersdorfer P; Housman DE; Messer A; Huston JS
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4764-9. PubMed ID: 11296304
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation.
    Zhou H; Li SH; Li XJ
    J Biol Chem; 2001 Dec; 276(51):48417-24. PubMed ID: 11606565
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Huntingtin aggregation and toxicity in Huntington's disease.
    Bates G
    Lancet; 2003 May; 361(9369):1642-4. PubMed ID: 12747895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.