These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 21916458)

  • 21. The molecular tweezer CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy.
    Herrera-Vaquero M; Bouquio D; Kallab M; Biggs K; Nair G; Ochoa J; Heras-Garvin A; Heid C; Hadrovic I; Poewe W; Wenning GK; Klärner FG; Schrader T; Bitan G; Stefanova N
    Biochim Biophys Acta Mol Basis Dis; 2019 Nov; 1865(11):165513. PubMed ID: 31319154
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications.
    Shahpasand-Kroner H; Siddique I; Malik R; Linares GR; Ivanova MI; Ichida J; Weil T; Münch J; Sanchez-Garcia E; Klärner FG; Schrader T; Bitan G
    Pharmacol Rev; 2023 Mar; 75(2):263-308. PubMed ID: 36549866
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator.
    Nshanian M; Lantz C; Wongkongkathep P; Schrader T; Klärner FG; Blümke A; Despres C; Ehrmann M; Smet-Nocca C; Bitan G; Loo JA
    J Am Soc Mass Spectrom; 2019 Jan; 30(1):16-23. PubMed ID: 30062477
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Aβ(39-42) modulates Aβ oligomerization but not fibril formation.
    Gessel MM; Wu C; Li H; Bitan G; Shea JE; Bowers MT
    Biochemistry; 2012 Jan; 51(1):108-17. PubMed ID: 22129303
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Understanding amyloid fibril nucleation and aβ oligomer/drug interactions from computer simulations.
    Nguyen P; Derreumaux P
    Acc Chem Res; 2014 Feb; 47(2):603-11. PubMed ID: 24368046
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A molecular tweezer antagonizes seminal amyloids and HIV infection.
    Lump E; Castellano LM; Meier C; Seeliger J; Erwin N; Sperlich B; Stürzel CM; Usmani S; Hammond RM; von Einem J; Gerold G; Kreppel F; Bravo-Rodriguez K; Pietschmann T; Holmes VM; Palesch D; Zirafi O; Weissman D; Sowislok A; Wettig B; Heid C; Kirchhoff F; Weil T; Klärner FG; Schrader T; Bitan G; Sanchez-Garcia E; Winter R; Shorter J; Münch J
    Elife; 2015 Aug; 4():. PubMed ID: 26284498
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species.
    Ferrão-Gonzales AD; Robbs BK; Moreau VH; Ferreira A; Juliano L; Valente AP; Almeida FC; Silva JL; Foguel D
    J Biol Chem; 2005 Oct; 280(41):34747-54. PubMed ID: 16041062
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Impact of K16A and K28A mutation on the structure and dynamics of amyloid-β
    Shuaib S; Saini RK; Goyal D; Goyal B
    J Biomol Struct Dyn; 2020 Feb; 38(3):708-721. PubMed ID: 30821624
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Supramolecular inhibition of amyloid fibrillation by cucurbit[7]uril.
    Lee HH; Choi TS; Lee SJ; Lee JW; Park J; Ko YH; Kim WJ; Kim K; Kim HI
    Angew Chem Int Ed Engl; 2014 Jul; 53(29):7461-5. PubMed ID: 24841324
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease.
    Monaco A; Maffia V; Sorrentino NC; Sambri I; Ezhova Y; Giuliano T; Cacace V; Nusco E; De Risi M; De Leonibus E; Schrader T; Klärner FG; Bitan G; Fraldi A
    Mol Ther; 2020 Apr; 28(4):1167-1176. PubMed ID: 32087148
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.
    Hughes E; Burke RM; Doig AJ
    J Biol Chem; 2000 Aug; 275(33):25109-15. PubMed ID: 10825171
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Modulation of Amyloid β-Protein (Aβ) Assembly by Homologous C-Terminal Fragments as a Strategy for Inhibiting Aβ Toxicity.
    Li H; Rahimi F; Bitan G
    ACS Chem Neurosci; 2016 Jul; 7(7):845-56. PubMed ID: 27322435
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The role of G protein activation in the toxicity of amyloidogenic Abeta-(1-40), Abeta-(25-35), and bovine calcitonin.
    Rymer DL; Good TA
    J Biol Chem; 2001 Jan; 276(4):2523-30. PubMed ID: 11060290
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Specific keratinase derived designer peptides potently inhibit A
    Rajput R; G L B; Srivastava A; Wahi D; Shrivastava N; Kundu B; Grover A
    Biochem J; 2019 Jun; 476(12):1817-1841. PubMed ID: 31138770
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Aromatic interactions by molecular tweezers and clips in chemical and biological systems.
    Klärner FG; Schrader T
    Acc Chem Res; 2013 Apr; 46(4):967-78. PubMed ID: 22725723
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The ongoing search for small molecules to study metal-associated amyloid-β species in Alzheimer's disease.
    Savelieff MG; DeToma AS; Derrick JS; Lim MH
    Acc Chem Res; 2014 Aug; 47(8):2475-82. PubMed ID: 25080056
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid beta-protein assembly and toxicity.
    Ono K; Condron MM; Teplow DB
    J Biol Chem; 2010 Jul; 285(30):23186-97. PubMed ID: 20452980
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Computational investigations on the dynamic binding effect of molecular tweezer CLR01 toward intrinsically disordered HIV-1 Nef.
    Bhattarai A; Emerson IA
    Biotechnol Appl Biochem; 2021 Jun; 68(3):513-530. PubMed ID: 32447788
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF.
    Lowe TL; Strzelec A; Kiessling LL; Murphy RM
    Biochemistry; 2001 Jul; 40(26):7882-9. PubMed ID: 11425316
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibitors of amyloid beta-protein aggregation mediated by GM1-containing raft-like membranes.
    Matsuzaki K; Noguch T; Wakabayashi M; Ikeda K; Okada T; Ohashi Y; Hoshino M; Naiki H
    Biochim Biophys Acta; 2007 Jan; 1768(1):122-30. PubMed ID: 17069749
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.