These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 21916509)

  • 1. Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays.
    Semenova MN; Kiselyov AS; Tsyganov DV; Konyushkin LD; Firgang SI; Semenov RV; Malyshev OR; Raihstat MM; Fuchs F; Stielow A; Lantow M; Philchenkov AA; Zavelevich MP; Zefirov NS; Kuznetsov SA; Semenov VV
    J Med Chem; 2011 Oct; 54(20):7138-49. PubMed ID: 21916509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and comparative evaluation of 4-oxa- and 4-aza-podophyllotoxins as antiproliferative microtubule destabilizing agents.
    Chernysheva NB; Tsyganov DV; Philchenkov AA; Zavelevich MP; Kiselyov AS; Semenov RV; Semenova MN; Semenov VV
    Bioorg Med Chem Lett; 2012 Apr; 22(7):2590-3. PubMed ID: 22370267
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays.
    Kiselyov AS; Semenova MN; Chernyshova NB; Leitao A; Samet AV; Kislyi KA; Raihstat MM; Oprea T; Lemcke H; Lantow M; Weiss DG; Ikizalp NN; Kuznetsov SA; Semenov VV
    Eur J Med Chem; 2010 May; 45(5):1683-97. PubMed ID: 20110137
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.
    Abad A; López-Pérez JL; del Olmo E; García-Fernández LF; Francesch A; Trigili C; Barasoain I; Andreu JM; Díaz JF; San Feliciano A
    J Med Chem; 2012 Aug; 55(15):6724-37. PubMed ID: 22607205
    [TBL] [Abstract][Full Text] [Related]  

  • 5. cis-Restricted 3-aminopyrazole analogues of combretastatins: synthesis from plant polyalkoxybenzenes and biological evaluation in the cytotoxicity and phenotypic sea urchin embryo assays.
    Tsyganov DV; Konyushkin LD; Karmanova IB; Firgang SI; Strelenko YA; Semenova MN; Kiselyov AS; Semenov VV
    J Nat Prod; 2013 Aug; 76(8):1485-91. PubMed ID: 23924236
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents.
    Kamal A; Suresh P; Mallareddy A; Kumar BA; Reddy PV; Raju P; Tamboli JR; Shaik TB; Jain N; Kalivendi SV
    Bioorg Med Chem; 2011 Apr; 19(7):2349-58. PubMed ID: 21402478
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity.
    Semenov VV; Tsyganov DV; Semenova MN; Chuprov-Netochin RN; Raihstat MM; Konyushkin LD; Volynchuk PB; Marusich EI; Nazarenko VV; Leonov SV; Kiselyov AS
    J Nat Prod; 2016 May; 79(5):1429-38. PubMed ID: 27100701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative in vivo evaluation of polyalkoxy substituted 4H-chromenes and oxa-podophyllotoxins as microtubule destabilizing agents in the phenotypic sea urchin embryo assay.
    Semenova MN; Tsyganov DV; Malyshev OR; Ershov OV; Bardasov IN; Semenov RV; Kiselyov AS; Semenov VV
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3914-8. PubMed ID: 24997684
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.
    Semenova MN; Demchuk DV; Tsyganov DV; Chernysheva NB; Samet AV; Silyanova EA; Kislyi VP; Maksimenko AS; Varakutin AE; Konyushkin LD; Raihstat MM; Kiselyov AS; Semenov VV
    ACS Comb Sci; 2018 Dec; 20(12):700-721. PubMed ID: 30452225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3-(5-)-Amino-o-diarylisoxazoles: regioselective synthesis and antitubulin activity.
    Tsyganov DV; Khrustalev VN; Konyushkin LD; Raihstat MM; Firgang SI; Semenov RV; Kiselyov AS; Semenova MN; Semenov VV
    Eur J Med Chem; 2014 Feb; 73():112-25. PubMed ID: 24388833
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A; Tamboli JR; Nayak VL; Adil SF; Vishnuvardhan MV; Ramakrishna S
    Bioorg Med Chem; 2014 May; 22(9):2714-23. PubMed ID: 24721832
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of chalcone-amidobenzothiazole conjugates as antimitotic and apoptotic inducing agents.
    Kamal A; Mallareddy A; Suresh P; Shaik TB; Lakshma Nayak V; Kishor C; Shetti RV; Sankara Rao N; Tamboli JR; Ramakrishna S; Addlagatta A
    Bioorg Med Chem; 2012 Jun; 20(11):3480-92. PubMed ID: 22543234
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
    J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.
    Demchuk DV; Samet AV; Chernysheva NB; Ushkarov VI; Stashina GA; Konyushkin LD; Raihstat MM; Firgang SI; Philchenkov AA; Zavelevich MP; Kuiava LM; Chekhun VF; Blokhin DY; Kiselyov AS; Semenova MN; Semenov VV
    Bioorg Med Chem; 2014 Jan; 22(2):738-55. PubMed ID: 24387982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents.
    Reddy MA; Jain N; Yada D; Kishore C; Vangala JR; P Surendra R; Addlagatta A; Kalivendi SV; Sreedhar B
    J Med Chem; 2011 Oct; 54(19):6751-60. PubMed ID: 21851083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies.
    Semenov VV; Lichitsky BV; Komogortsev AN; Dudinov AA; Krayushkin MM; Konyushkin LD; Atamanenko OP; Karmanova IB; Strelenko YA; Shor B; Semenova MN; Kiselyov AS
    Eur J Med Chem; 2017 Jan; 125():573-585. PubMed ID: 27718473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phenylcinnamides as novel antimitotic agents.
    Leslie BJ; Holaday CR; Nguyen T; Hergenrother PJ
    J Med Chem; 2010 May; 53(10):3964-72. PubMed ID: 20411988
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y; Wei D; Zhao Y; Cheng W; Lu Y; Ma Y; Li X; Han C; Wei Y; Cao H; Zhao C
    Bioorg Med Chem; 2012 Nov; 20(21):6285-95. PubMed ID: 23022053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines as a new class of potent antitubulin agents.
    Lo YH; Lin CC; Lin CF; Lin YT; Duh TH; Hong YR; Yang SH; Lin SR; Yang SC; Chang LS; Wu MJ
    J Med Chem; 2008 May; 51(9):2682-8. PubMed ID: 18386884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z; Zhou Z; Tian W; Fan X; Xue D; Yu L; Yu Q; Long YQ
    ChemMedChem; 2012 Apr; 7(4):680-93. PubMed ID: 22311585
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.