These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 21920000)

  • 1. QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells.
    Chen MC; Pan SL; Shi Q; Xiao Z; Lee KH; Li TK; Teng CM
    Cancer Sci; 2012 Jan; 103(1):80-7. PubMed ID: 21920000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
    Qin Y; Meng L; Hu C; Duan W; Zuo Z; Lin L; Zhang X; Ding J
    Mol Cancer Ther; 2007 Sep; 6(9):2429-40. PubMed ID: 17876042
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA topoisomerase II inhibition potentiates osimertinib's therapeutic efficacy in EGFR-mutant non-small cell lung cancer models.
    Chen Z; Vallega KA; Wang D; Quan Z; Fan S; Wang Q; Leal T; Ramalingam SS; Sun SY
    J Clin Invest; 2024 Mar; 134(10):. PubMed ID: 38451729
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells.
    Wu SY; Pan SL; Xiao ZY; Hsu JL; Chen MC; Lee KH; Teng CM
    PLoS One; 2014; 9(11):e112220. PubMed ID: 25372714
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II.
    Xue X; Qu XJ; Gao ZH; Sun CC; Liu HP; Zhao CR; Cheng YN; Lou HX
    Invest New Drugs; 2012 Feb; 30(1):212-22. PubMed ID: 20924640
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tirapazamine: a hypoxia-activated topoisomerase II poison.
    Peters KB; Brown JM
    Cancer Res; 2002 Sep; 62(18):5248-53. PubMed ID: 12234992
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells.
    Deng S; Yan T; Nikolova T; Fuhrmann D; Nemecek A; Gödtel-Armbrust U; Kaina B; Wojnowski L
    Br J Pharmacol; 2015 May; 172(9):2246-57. PubMed ID: 25521189
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CS1 is a novel topoisomerase IIα inhibitor with favorable drug resistance profiles.
    Shen Y; Chen W; Zhao B; Hao H; Li Z; Lu C; Shen Y
    Biochem Biophys Res Commun; 2014 Oct; 453(3):302-8. PubMed ID: 25242524
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma.
    Tabata M; Tabata R; Grabowski DR; Bukowski RM; Ganapathi MK; Ganapathi R
    J Biol Chem; 2001 Mar; 276(11):8029-36. PubMed ID: 11115510
    [TBL] [Abstract][Full Text] [Related]  

  • 10. B1, a novel topoisomerase II inhibitor, induces apoptosis and cell cycle G1 arrest in lung adenocarcinoma A549 cells.
    Cheng MH; Yang YC; Wong YH; Chen TR; Lee CY; Yang CC; Chen SH; Yang IN; Yang YS; Huang HS; Yang CY; Huang MS; Chiu HF
    Anticancer Drugs; 2012 Feb; 23(2):191-9. PubMed ID: 22008852
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Investigation of the mechanism and apoptotic pathway induced by 4β cinnamido linked podophyllotoxins against human lung cancer cells A549.
    Kamal A; Nayak VL; Bagul C; Vishnuvardhan MV; Mallareddy A
    Apoptosis; 2015 Nov; 20(11):1518-29. PubMed ID: 26386574
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer.
    Chien CM; Yang JC; Wu PH; Wu CY; Chen GY; Wu YC; Chou CK; Tseng CH; Chen YL; Wang LF; Chiu CC
    Phytomedicine; 2019 Feb; 54():109-119. PubMed ID: 30668360
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human multiple myeloma cells are sensitized to topoisomerase II inhibitors by CRM1 inhibition.
    Turner JG; Marchion DC; Dawson JL; Emmons MF; Hazlehurst LA; Washausen P; Sullivan DM
    Cancer Res; 2009 Sep; 69(17):6899-905. PubMed ID: 19690141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A cysteine-reactive alkyl hydroquinone modifies topoisomerase IIα, enhances DNA breakage, and induces apoptosis in cancer cells.
    Lin TY; Huang CP; Au LC; Chang YW; Hu CY; Lin SB
    Chem Res Toxicol; 2012 Nov; 25(11):2340-51. PubMed ID: 23088786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents.
    Kamal A; Suresh P; Ramaiah MJ; Mallareddy A; Imthiajali S; Pushpavalli SN; Lavanya A; Pal-Bhadra M
    Bioorg Med Chem; 2012 Mar; 20(6):2054-66. PubMed ID: 22364746
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting Topoisomerase II Activity in NSCLC with 9-Aminoacridine Derivatives.
    Ferguson DM; Jacobson BA; Jay-Dixon J; Patel MR; Kratzke RA; Raza A
    Anticancer Res; 2015 Oct; 35(10):5211-7. PubMed ID: 26408679
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CIP-36, a novel topoisomerase II-targeting agent, induces the apoptosis of multidrug-resistant cancer cells in vitro.
    Cao B; Chen H; Gao Y; Niu C; Zhang Y; Li L
    Int J Mol Med; 2015 Mar; 35(3):771-6. PubMed ID: 25592869
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide.
    Melo-Hanchuk TD; Slepicka PF; Pelegrini AL; Menck CFM; Kobarg J
    J Cell Biochem; 2019 Oct; 120(10):16853-16866. PubMed ID: 31090963
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HU-331 is a catalytic inhibitor of topoisomerase IIα.
    Regal KM; Mercer SL; Deweese JE
    Chem Res Toxicol; 2014 Dec; 27(12):2044-51. PubMed ID: 25409338
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors.
    Park S; Hong E; Kwak SY; Jun KY; Lee ES; Kwon Y; Na Y
    Eur J Med Chem; 2016 Nov; 123():211-225. PubMed ID: 27484510
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.