BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 21920762)

  • 1. Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway.
    Krishnegowda G; Prakasha Gowda AS; Tagaram HR; Carroll KF; Irby RB; Sharma AK; Amin S
    Bioorg Med Chem; 2011 Oct; 19(20):6006-14. PubMed ID: 21920762
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities.
    Yang M; Liu H; Zhang Y; Wang X; Xu Z
    Curr Top Med Chem; 2020; 20(16):1461-1467. PubMed ID: 31994464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway.
    Kamal A; Rao AV; Nayak VL; Reddy NV; Swapna K; Ramakrishna G; Alvala M
    Org Biomol Chem; 2014 Dec; 12(48):9864-80. PubMed ID: 25354805
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
    Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Triazole linked mono carbonyl curcumin-isatin bifunctional hybrids as novel anti tubulin agents: Design, synthesis, biological evaluation and molecular modeling studies.
    Sharma S; Gupta MK; Saxena AK; Bedi PM
    Bioorg Med Chem; 2015 Nov; 23(22):7165-80. PubMed ID: 26515041
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of benzo[b]furans as inhibitors of tubulin polymerization and inducers of apoptosis.
    Kamal A; Reddy NV; Nayak VL; Reddy VS; Prasad B; Nimbarte VD; Srinivasulu V; Vishnuvardhan MV; Reddy CS
    ChemMedChem; 2014 Jan; 9(1):117-28. PubMed ID: 24203459
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A; Tamboli JR; Nayak VL; Adil SF; Vishnuvardhan MV; Ramakrishna S
    Bioorg Med Chem; 2014 May; 22(9):2714-23. PubMed ID: 24721832
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A; Khodarahmi G; Forootanfar H; Hassanzadeh F; Hakimelahi GH
    Chem Biodivers; 2018 Mar; 15(3):e1700518. PubMed ID: 29292595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C; Sathish M; Anchi P; Tokala R; Lakshmi UJ; Reddy VG; Shankaraiah N; Godugu C; Kamal A
    ChemMedChem; 2019 Dec; 14(24):2052-2060. PubMed ID: 31674147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R
    Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S; Tokala R; Bajaj DM; Nagesh N; Bokara KK; Kiranmai G; Lakshmi UJ; Vadlamani S; Talla V; Shankaraiah N
    Bioorg Chem; 2019 Dec; 93():103317. PubMed ID: 31586714
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors.
    Kamal A; Srinivasa Reddy T; Polepalli S; Paidakula S; Srinivasulu V; Ganga Reddy V; Jain N; Shankaraiah N
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3356-60. PubMed ID: 24953821
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, Synthesis and Molecular Docking Studies of Novel Indole-Pyrimidine Hybrids as Tubulin Polymerization Inhibitors.
    Hu MJ; Zhang B; Yang HK; Liu Y; Chen YR; Ma TZ; Lu L; You WW; Zhao PL
    Chem Biol Drug Des; 2015 Dec; 86(6):1491-500. PubMed ID: 26177395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y; Lin H; Ou C; Cao Y; An B; Yan J; Li X
    Eur J Med Chem; 2019 Nov; 182():111670. PubMed ID: 31499359
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of N-alkyl-N-(4-methoxyphenyl)pyridin-2-amines as a new class of tubulin polymerization inhibitors.
    Wang XF; Ohkoshi E; Wang SB; Hamel E; Bastow KF; Morris-Natschke SL; Lee KH; Xie L
    Bioorg Med Chem; 2013 Feb; 21(3):632-42. PubMed ID: 23274123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT; Shi TQ; Zhu HL; Liu CH
    Bioorg Med Chem; 2019 Feb; 27(3):502-515. PubMed ID: 30606674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S; An B; Li Y; Luo X; Li X; Jia X
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1769-1775. PubMed ID: 29673981
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity.
    Moise IM; Bîcu E; Farce A; Dubois J; Ghinet A
    Bioorg Chem; 2020 Oct; 103():104184. PubMed ID: 32891861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-Anilino-3-Aroylquinolines as Potent Tubulin Polymerization Inhibitors.
    Srikanth PS; Nayak VL; Suresh Babu K; Kumar GB; Ravikumar A; Kamal A
    ChemMedChem; 2016 Sep; 11(18):2050-62. PubMed ID: 27465681
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.