BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

640 related articles for article (PubMed ID: 21922131)

  • 1. Activation of PI3 kinase/Akt/HIF-1α pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma.
    Jiao M; Nan KJ
    Int J Oncol; 2012 Feb; 40(2):461-8. PubMed ID: 21922131
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway.
    Wang H; Zhang C; Xu L; Zang K; Ning Z; Jiang F; Chi H; Zhu X; Meng Z
    Oncotarget; 2016 Apr; 7(15):20193-208. PubMed ID: 26958938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PI3 kinase/Akt/HIF-1α pathway is associated with hypoxia-induced epithelial-mesenchymal transition in fibroblast-like synoviocytes of rheumatoid arthritis.
    Li GQ; Zhang Y; Liu D; Qian YY; Zhang H; Guo SY; Sunagawa M; Hisamitsu T; Liu YQ
    Mol Cell Biochem; 2013 Jan; 372(1-2):221-31. PubMed ID: 23001847
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sanguinarine inhibits epithelial-mesenchymal transition via targeting HIF-1α/TGF-β feed-forward loop in hepatocellular carcinoma.
    Su Q; Fan M; Wang J; Ullah A; Ghauri MA; Dai B; Zhan Y; Zhang D; Zhang Y
    Cell Death Dis; 2019 Dec; 10(12):939. PubMed ID: 31819036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells.
    Lau CK; Yang ZF; Ho DW; Ng MN; Yeoh GC; Poon RT; Fan ST
    Clin Cancer Res; 2009 May; 15(10):3462-71. PubMed ID: 19447872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2.
    Ma L; Li G; Zhu H; Dong X; Zhao D; Jiang X; Li J; Qiao H; Ni S; Sun X
    Cancer Lett; 2014 Dec; 355(1):96-105. PubMed ID: 25218350
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Canagliflozin Modulates Hypoxia-Induced Metastasis, Angiogenesis and Glycolysis by Decreasing HIF-1α Protein Synthesis via AKT/mTOR Pathway.
    Luo J; Sun P; Zhang X; Lin G; Xin Q; Niu Y; Chen Y; Xu N; Zhang Y; Xie W
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948132
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combining combretastatin A4 phosphate with ginsenoside Rd synergistically inhibited hepatocellular carcinoma by reducing HIF-1α via PI3K/AKT/mTOR signalling pathway.
    Yang X; Gao M; Miao M; Jiang C; Zhang D; Yin Z; Ni Y; Chen J; Zhang J
    J Pharm Pharmacol; 2021 Mar; 73(2):263-271. PubMed ID: 33793802
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia Accelerates Aggressiveness of Hepatocellular Carcinoma Cells Involving Oxidative Stress, Epithelial-Mesenchymal Transition and Non-Canonical Hedgehog Signaling.
    Liu Z; Tu K; Wang Y; Yao B; Li Q; Wang L; Dou C; Liu Q; Zheng X
    Cell Physiol Biochem; 2017; 44(5):1856-1868. PubMed ID: 29237157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling.
    Zhang Q; Bai X; Chen W; Ma T; Hu Q; Liang C; Xie S; Chen C; Hu L; Xu S; Liang T
    Carcinogenesis; 2013 May; 34(5):962-73. PubMed ID: 23358852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of phosphatidylinositol 3-kinase/AKT/snail signaling pathway contributes to epithelial-mesenchymal transition-induced multi-drug resistance to sorafenib in hepatocellular carcinoma cells.
    Dong J; Zhai B; Sun W; Hu F; Cheng H; Xu J
    PLoS One; 2017; 12(9):e0185088. PubMed ID: 28934275
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of COX-2 expression and epithelial-to-mesenchymal transition by hypoxia-inducible factor-1α is associated with poor prognosis in hepatocellular carcinoma patients post TACE surgery.
    Huang M; Wang L; Chen J; Bai M; Zhou C; Liu S; Lin Q
    Int J Oncol; 2016 May; 48(5):2144-54. PubMed ID: 26984380
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PI3 kinase/Akt signaling mediates epithelial-mesenchymal transition in hypoxic hepatocellular carcinoma cells.
    Yan W; Fu Y; Tian D; Liao J; Liu M; Wang B; Xia L; Zhu Q; Luo M
    Biochem Biophys Res Commun; 2009 May; 382(3):631-6. PubMed ID: 19303863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plantamajoside inhibits the proliferation and epithelial-to-mesenchymal transition in hepatocellular carcinoma cells via modulating hypoxia-inducible factor-1α-dependent gene expression.
    Yin W; Xu J; Li C; Dai X; Wu T; Wen J
    Cell Biol Int; 2020 Aug; 44(8):1616-1627. PubMed ID: 32239594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zinc Attenuates Tubulointerstitial Fibrosis in Diabetic Nephropathy Via Inhibition of HIF Through PI-3K Signaling.
    Zhang X; Liang D; Fan J; Lian X; Zhao Y; Wang X; Chi ZH; Zhang P
    Biol Trace Elem Res; 2016 Oct; 173(2):372-83. PubMed ID: 26956696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma.
    Liang Y; Zheng T; Song R; Wang J; Yin D; Wang L; Liu H; Tian L; Fang X; Meng X; Jiang H; Liu J; Liu L
    Hepatology; 2013 May; 57(5):1847-57. PubMed ID: 23299930
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway.
    Gong T; Cui L; Wang H; Wang H; Han N
    J Transl Med; 2018 Jun; 16(1):164. PubMed ID: 29898734
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway.
    Wang XJ; Feng CW; Li M
    Mol Cell Biochem; 2013 Aug; 380(1-2):57-66. PubMed ID: 23625205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway.
    Yeh YH; Hsiao HF; Yeh YC; Chen TW; Li TK
    J Exp Clin Cancer Res; 2018 Mar; 37(1):70. PubMed ID: 29587825
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.