237 related articles for article (PubMed ID: 21922321)
1. A common variant upstream of the PAX6 gene influences islet function in man.
Ahlqvist E; Turrini F; Lang ST; Taneera J; Zhou Y; Almgren P; Hansson O; Isomaa B; Tuomi T; Eriksson K; Eriksson JG; Lyssenko V; Groop L
Diabetologia; 2012 Jan; 55(1):94-104. PubMed ID: 21922321
[TBL] [Abstract][Full Text] [Related]
2. High-fat diet induces early-onset diabetes in heterozygous Pax6 mutant mice.
Chen Y; Feng R; Wang H; Wei R; Yang J; Wang L; Wang H; Zhang L; Hong TP; Wen J
Diabetes Metab Res Rev; 2014 Sep; 30(6):467-75. PubMed ID: 24925705
[TBL] [Abstract][Full Text] [Related]
3. Pax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing.
Liu T; Zhao Y; Tang N; Feng R; Yang X; Lu N; Wen J; Li L
PLoS One; 2012; 7(10):e46934. PubMed ID: 23056534
[TBL] [Abstract][Full Text] [Related]
4. Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3).
Wen JH; Chen YY; Song SJ; Ding J; Gao Y; Hu QK; Feng RP; Liu YZ; Ren GC; Zhang CY; Hong TP; Gao X; Li LS
Diabetologia; 2009 Mar; 52(3):504-13. PubMed ID: 19034419
[TBL] [Abstract][Full Text] [Related]
5. Adult pancreatic islets require differential pax6 gene dosage.
Hamasaki A; Yamada Y; Kurose T; Ban N; Nagashima K; Takahashi A; Fujimoto S; Shimono D; Fujiwara M; Toyokuni S; Seino Y; Inagaki N
Biochem Biophys Res Commun; 2007 Feb; 353(1):40-6. PubMed ID: 17178107
[TBL] [Abstract][Full Text] [Related]
6. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell.
Kulzer JR; Stitzel ML; Morken MA; Huyghe JR; Fuchsberger C; Kuusisto J; Laakso M; Boehnke M; Collins FS; Mohlke KL
Am J Hum Genet; 2014 Feb; 94(2):186-97. PubMed ID: 24439111
[TBL] [Abstract][Full Text] [Related]
7. Mutant PAX6 downregulates prohormone convertase 2 expression in mouse islets.
Chen Y; Cao W; Zhou S; Shen L; Wen J
Exp Biol Med (Maywood); 2013 Nov; 238(11):1259-64. PubMed ID: 24047795
[TBL] [Abstract][Full Text] [Related]
8. High-fat diet induced insulin resistance in pregnant rats through pancreatic pax6 signaling pathway.
Wu H; Liu Y; Wang H; Xu X
Int J Clin Exp Pathol; 2015; 8(5):5196-202. PubMed ID: 26191217
[TBL] [Abstract][Full Text] [Related]
9. CTCF mediates effect of insulin on glucagon expression.
Tsui S; Gao J; Wang C; Lu L
Exp Cell Res; 2012 May; 318(8):887-95. PubMed ID: 22426149
[TBL] [Abstract][Full Text] [Related]
10. The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas.
Hart AW; Mella S; Mendrychowski J; van Heyningen V; Kleinjan DA
PLoS One; 2013; 8(1):e54173. PubMed ID: 23326594
[TBL] [Abstract][Full Text] [Related]
11. Chronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (α-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cells.
Piro S; Mascali LG; Urbano F; Filippello A; Malaguarnera R; Calanna S; Rabuazzo AM; Purrello F
PLoS One; 2014; 9(2):e90093. PubMed ID: 24587221
[TBL] [Abstract][Full Text] [Related]
12. Pax6 is a key component of regulated glucagon secretion.
Gosmain Y; Cheyssac C; Masson MH; Guérardel A; Poisson C; Philippe J
Endocrinology; 2012 Sep; 153(9):4204-15. PubMed ID: 22778220
[TBL] [Abstract][Full Text] [Related]
13. In vitro effects of mycophenolic acid on survival, function, and gene expression of pancreatic beta-cells.
Gallo R; Natale M; Vendrame F; Boggi U; Filipponi F; Marchetti P; Laghi Pasini F; Dotta F
Acta Diabetol; 2012 Dec; 49 Suppl 1():S123-31. PubMed ID: 22249339
[TBL] [Abstract][Full Text] [Related]
14. Microphthalmia transcription factor regulates pancreatic β-cell function.
Mazur MA; Winkler M; Ganic E; Colberg JK; Johansson JK; Bennet H; Fex M; Nuber UA; Artner I
Diabetes; 2013 Aug; 62(8):2834-42. PubMed ID: 23610061
[TBL] [Abstract][Full Text] [Related]
15. The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6.
Wolf G; Hessabi B; Karkour A; Henrion U; Dahlhaus M; Ostmann A; Giese B; Fraunholz M; Grabarczyk P; Jack R; Walther R
Mol Endocrinol; 2010 Dec; 24(12):2331-42. PubMed ID: 20943817
[TBL] [Abstract][Full Text] [Related]
16. Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion.
Gosmain Y; Katz LS; Masson MH; Cheyssac C; Poisson C; Philippe J
Mol Endocrinol; 2012 Apr; 26(4):696-709. PubMed ID: 22403172
[TBL] [Abstract][Full Text] [Related]
17. Pax6 haploinsufficiency causes abnormal metabolic homeostasis by down-regulating glucagon-like peptide 1 in mice.
Ding J; Gao Y; Zhao J; Yan H; Guo SY; Zhang QX; Li LS; Gao X
Endocrinology; 2009 May; 150(5):2136-44. PubMed ID: 19116343
[TBL] [Abstract][Full Text] [Related]
18. Glucose modulates Pax6 expression through the JNK/p38 MAP kinase pathway in pancreatic beta-cells.
Balakrishnan S; Sadasivam M; Kannan A; Panneerselvam A; Prahalathan C
Life Sci; 2014 Jul; 109(1):1-7. PubMed ID: 24953606
[TBL] [Abstract][Full Text] [Related]
19. Mutation of the Pax6 gene causes impaired glucose-stimulated insulin secretion.
Kuroda A; Kaneto H; Fujitani Y; Watada H; Nakatani Y; Kajimoto Y; Matsuhisa M; Yamasakai Y; Fujiwara M
Diabetologia; 2004 Nov; 47(11):2039-41. PubMed ID: 15565366
[No Abstract] [Full Text] [Related]
20. A peroxisome proliferator-activated receptor gamma-retinoid X receptor heterodimer physically interacts with the transcriptional activator PAX6 to inhibit glucagon gene transcription.
Krätzner R; Fröhlich F; Lepler K; Schröder M; Röher K; Dickel C; Tzvetkov MV; Quentin T; Oetjen E; Knepel W
Mol Pharmacol; 2008 Feb; 73(2):509-17. PubMed ID: 17962386
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]