191 related articles for article (PubMed ID: 21925487)
1. Enhanced glutathione depletion, protein adduct formation, and cytotoxicity following exposure to 4-hydroxy-2-nonenal (HNE) in cells expressing human multidrug resistance protein-1 (MRP1) together with human glutathione S-transferase-M1 (GSTM1).
Rudd LP; Kabler SL; Morrow CS; Townsend AJ
Chem Biol Interact; 2011 Nov; 194(2-3):113-9. PubMed ID: 21925487
[TBL] [Abstract][Full Text] [Related]
2. Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1.
Diah SK; Smitherman PK; Townsend AJ; Morrow CS
Toxicol Appl Pharmacol; 1999 Jun; 157(2):85-93. PubMed ID: 10366541
[TBL] [Abstract][Full Text] [Related]
3. Differential roles of 3H-1,2-dithiole-3-thione-induced glutathione, glutathione S-transferase and aldose reductase in protecting against 4-hydroxy-2-nonenal toxicity in cultured cardiomyocytes.
Li Y; Cao Z; Zhu H; Trush MA
Arch Biochem Biophys; 2005 Jul; 439(1):80-90. PubMed ID: 15946642
[TBL] [Abstract][Full Text] [Related]
4. Multidrug resistance associated protein 1 together with glutathione plays a protective role against 4-hydroxy-2-nonenal-induced oxidative stress in bovine aortic endothelial cells.
Takahashi K; Tatsunami R; Sato K; Tampo Y
Biol Pharm Bull; 2012; 35(8):1269-74. PubMed ID: 22863924
[TBL] [Abstract][Full Text] [Related]
5. Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver.
Reichard JF; Vasiliou V; Petersen DR
Biochim Biophys Acta; 2000 Sep; 1487(2-3):222-32. PubMed ID: 11018474
[TBL] [Abstract][Full Text] [Related]
6. Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases.
Sundberg K; Dreij K; Seidel A; Jernström B
Chem Res Toxicol; 2002 Feb; 15(2):170-9. PubMed ID: 11849043
[TBL] [Abstract][Full Text] [Related]
7. Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes.
Lok HC; Rahmanto YS; Hawkins CL; Kalinowski DS; Morrow CS; Townsend AJ; Ponka P; Richardson DR
J Biol Chem; 2012 Jan; 287(1):607-618. PubMed ID: 22084240
[TBL] [Abstract][Full Text] [Related]
8. Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1.
Watts RN; Hawkins C; Ponka P; Richardson DR
Proc Natl Acad Sci U S A; 2006 May; 103(20):7670-5. PubMed ID: 16679408
[TBL] [Abstract][Full Text] [Related]
9. Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate.
Knoll N; Ruhe C; Veeriah S; Sauer J; Glei M; Gallagher EP; Pool-Zobel BL
Toxicol Sci; 2005 Jul; 86(1):27-35. PubMed ID: 15829614
[TBL] [Abstract][Full Text] [Related]
10. Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1.
Peklak-Scott C; Townsend AJ; Morrow CS
Biochemistry; 2005 Mar; 44(11):4426-33. PubMed ID: 15766272
[TBL] [Abstract][Full Text] [Related]
11. The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal.
Jungsuwadee P; Zhao T; Stolarczyk EI; Paumi CM; Butterfield DA; St Clair DK; Vore M
Pharmacogenet Genomics; 2012 Apr; 22(4):273-84. PubMed ID: 22293538
[TBL] [Abstract][Full Text] [Related]
12. Endogenous glutathione adducts.
Blair IA
Curr Drug Metab; 2006 Dec; 7(8):853-72. PubMed ID: 17168687
[TBL] [Abstract][Full Text] [Related]
13. Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-E-nonenal (4-HNE) in hepatoma cells.
Tjalkens RB; Cook LW; Petersen DR
Arch Biochem Biophys; 1999 Jan; 361(1):113-9. PubMed ID: 9882435
[TBL] [Abstract][Full Text] [Related]
14. The role of chemically induced glutathione and glutathione S-transferase in protecting against 4-hydroxy-2-nonenal-mediated cytotoxicity in vascular smooth muscle cells.
Cao Z; Hardej D; Trombetta LD; Li Y
Cardiovasc Toxicol; 2003; 3(2):165-77. PubMed ID: 14501034
[TBL] [Abstract][Full Text] [Related]
15. Multidrug resistance protein MRP1, glutathione, and related enzymes. Their importance in acute myeloid leukemia.
van der Kolk DM; Vellenga E; Müller M; de Vries EG
Adv Exp Med Biol; 1999; 457():187-98. PubMed ID: 10500793
[TBL] [Abstract][Full Text] [Related]
16. The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase.
Hartley DP; Ruth JA; Petersen DR
Arch Biochem Biophys; 1995 Jan; 316(1):197-205. PubMed ID: 7840616
[TBL] [Abstract][Full Text] [Related]
17. Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required.
Leslie EM; Haimeur A; Waalkes MP
J Biol Chem; 2004 Jul; 279(31):32700-8. PubMed ID: 15161912
[TBL] [Abstract][Full Text] [Related]
18. Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicity.
Paumi CM; Ledford BG; Smitherman PK; Townsend AJ; Morrow CS
J Biol Chem; 2001 Mar; 276(11):7952-6. PubMed ID: 11115505
[TBL] [Abstract][Full Text] [Related]
19. Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells.
Morrow CS; Smitherman PK; Diah SK; Schneider E; Townsend AJ
J Biol Chem; 1998 Aug; 273(32):20114-20. PubMed ID: 9685354
[TBL] [Abstract][Full Text] [Related]
20. The balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas.
Uno K; Kato K; Kusaka G; Asano N; Iijima K; Shimosegawa T
Mol Carcinog; 2011 Oct; 50(10):781-90. PubMed ID: 21751261
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]