BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 21926168)

  • 1. Crystal structures of protein glutaminase and its pro forms converted into enzyme-substrate complex.
    Hashizume R; Maki Y; Mizutani K; Takahashi N; Matsubara H; Sugita A; Sato K; Yamaguchi S; Mikami B
    J Biol Chem; 2011 Nov; 286(44):38691-38702. PubMed ID: 21926168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.
    Smith AM; Brown WC; Harms E; Smith JL
    J Biol Chem; 2015 Feb; 290(9):5226-39. PubMed ID: 25568319
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of the catalytic activity of human factor XIIIa by site-directed mutagenesis.
    Hettasch JM; Greenberg CS
    J Biol Chem; 1994 Nov; 269(45):28309-13. PubMed ID: 7961769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 A crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase.
    Isupov MN; Obmolova G; Butterworth S; Badet-Denisot MA; Badet B; Polikarpov I; Littlechild JA; Teplyakov A
    Structure; 1996 Jul; 4(7):801-10. PubMed ID: 8805567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein-glutaminase from Chryseobacterium proteolyticum, an enzyme that deamidates glutaminyl residues in proteins. Purification, characterization and gene cloning.
    Yamaguchi S; Jeenes DJ; Archer DB
    Eur J Biochem; 2001 Mar; 268(5):1410-21. PubMed ID: 11231294
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.
    Brown G; Singer A; Proudfoot M; Skarina T; Kim Y; Chang C; Dementieva I; Kuznetsova E; Gonzalez CF; Joachimiak A; Savchenko A; Yakunin AF
    Biochemistry; 2008 May; 47(21):5724-35. PubMed ID: 18459799
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Fold-Independent Interface Residue Is Crucial for Complex Formation and Allosteric Signaling in Class I Glutamine Amidotransferases.
    Semmelmann F; Hupfeld E; Heizinger L; Merkl R; Sterner R
    Biochemistry; 2019 Jun; 58(22):2584-2588. PubMed ID: 31117390
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
    Sivaraman J; Nägler DK; Zhang R; Ménard R; Cygler M
    J Mol Biol; 2000 Jan; 295(4):939-51. PubMed ID: 10656802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. "Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage.
    McCluskey GD; Bearne SL
    Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2714-2727. PubMed ID: 30251661
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris.
    Yoshimune K; Shirakihara Y; Wakayama M; Yumoto I
    FEBS J; 2010 Feb; 277(3):738-48. PubMed ID: 20050917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA).
    Thangavelu K; Chong QY; Low BC; Sivaraman J
    Sci Rep; 2014 Jan; 4():3827. PubMed ID: 24451979
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense.
    Kashiwagi T; Yokoyama K; Ishikawa K; Ono K; Ejima D; Matsui H; Suzuki E
    J Biol Chem; 2002 Nov; 277(46):44252-60. PubMed ID: 12221081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (beta/alpha)8 barrel joins two active sites.
    Chaudhuri BN; Lange SC; Myers RS; Chittur SV; Davisson VJ; Smith JL
    Structure; 2001 Oct; 9(10):987-97. PubMed ID: 11591353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
    Waksman G; Krishna TS; Williams CH; Kuriyan J
    J Mol Biol; 1994 Feb; 236(3):800-16. PubMed ID: 8114095
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase.
    Guo B; Lin J; Ye K
    J Biol Chem; 2011 Jun; 286(24):21937-43. PubMed ID: 21543324
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
    Nguyen HA; Durden DL; Lavie A
    Sci Rep; 2017 Jan; 7():41643. PubMed ID: 28139703
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into cleavage specificity from the crystal structure of foot-and-mouth disease virus 3C protease complexed with a peptide substrate.
    Zunszain PA; Knox SR; Sweeney TR; Yang J; Roqué-Rosell N; Belsham GJ; Leatherbarrow RJ; Curry S
    J Mol Biol; 2010 Jan; 395(2):375-89. PubMed ID: 19883658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
    Kanitz M; Blanck S; Heine A; Gulyaeva AA; Gorbalenya AE; Ziebuhr J; Diederich WE
    Virology; 2019 Jul; 533():21-33. PubMed ID: 31078932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis.
    Liu H; Zheng G; Treber M; Dai J; Woldegiorgis G
    J Biol Chem; 2005 Feb; 280(6):4524-31. PubMed ID: 15579906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ordering of C-terminal loop and glutaminase domains of glucosamine-6-phosphate synthase promotes sugar ring opening and formation of the ammonia channel.
    Mouilleron S; Badet-Denisot MA; Golinelli-Pimpaneau B
    J Mol Biol; 2008 Apr; 377(4):1174-85. PubMed ID: 18295797
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.