BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 21927014)

  • 1. Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21(waf1/cip1)-independent pathway in human colorectal cancer cells.
    Kalimutho M; Minutolo A; Grelli S; Federici G; Bernardini S
    Acta Pharmacol Sin; 2011 Nov; 32(11):1387-96. PubMed ID: 21927014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
    Shin DY; Sung Kang H; Kim GY; Kim WJ; Yoo YH; Choi YH
    Biomed Pharmacother; 2013 May; 67(4):305-11. PubMed ID: 23582784
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of G2/M Cell Cycle Arrest via p38/p21
    Pai JT; Hsu MW; Leu YL; Chang KT; Weng MS
    Molecules; 2021 Aug; 26(17):. PubMed ID: 34500594
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk.
    Qi LW; Zhang Z; Zhang CF; Anderson S; Liu Q; Yuan CS; Wang CZ
    Am J Chin Med; 2015; 43(4):743-56. PubMed ID: 26119958
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance.
    Kalimutho M; Minutolo A; Grelli S; Formosa A; Sancesario G; Valentini A; Federici G; Bernardini S
    Cancer Chemother Pharmacol; 2011 Jun; 67(6):1299-312. PubMed ID: 20734047
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxaliplatin-induced gamma-H2AX activation via both p53-dependent and -independent pathways but is not associated with cell cycle arrest in human colorectal cancer cells.
    Chiu SJ; Lee YJ; Hsu TS; Chen WS
    Chem Biol Interact; 2009 Dec; 182(2-3):173-82. PubMed ID: 19735649
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of cisplatin, 5-fluorouracil, and radiation on cell cycle regulation and apoptosis in the hypopharyngeal carcinoma cell line.
    Lee BJ; Chon KM; Kim YS; An WG; Roh HJ; Goh EK; Wang SG
    Chemotherapy; 2005 May; 51(2-3):103-10. PubMed ID: 15886465
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
    Hayward RL; Schornagel QC; Tente R; Macpherson JS; Aird RE; Guichard S; Habtemariam A; Sadler P; Jodrell DI
    Cancer Chemother Pharmacol; 2005 Jun; 55(6):577-83. PubMed ID: 15726367
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells.
    Hata T; Yamamoto H; Ngan CY; Koi M; Takagi A; Damdinsuren B; Yasui M; Fujie Y; Matsuzaki T; Hemmi H; Xu X; Kitani K; Seki Y; Takemasa I; Ikeda M; Sekimoto M; Matsuura N; Monden M
    Mol Cancer Ther; 2005 Oct; 4(10):1585-94. PubMed ID: 16227409
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The small molecule AU14022 promotes colorectal cancer cell death via p53-mediated G2/M-phase arrest and mitochondria-mediated apoptosis.
    Ryu H; Nam KY; Kim JS; Hwang SG; Song JY; Ahn J
    J Cell Physiol; 2018 Jun; 233(6):4666-4676. PubMed ID: 29030986
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.
    Li Y; Shao J; Shen K; Xu Y; Liu J; Qian X
    J Cell Biochem; 2012 Oct; 113(10):3165-77. PubMed ID: 22593008
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents.
    Mujoo K; Watanabe M; Nakamura J; Khokhar AR; Siddik ZH
    J Cancer Res Clin Oncol; 2003 Dec; 129(12):709-18. PubMed ID: 14513366
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
    Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cepharanthine exhibits a potent anticancer activity in p53-mutated colorectal cancer cells through upregulation of p21Waf1/Cip1.
    Rattanawong A; Payon V; Limpanasittikul W; Boonkrai C; Mutirangura A; Wonganan P
    Oncol Rep; 2018 Jan; 39(1):227-238. PubMed ID: 29138869
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
    Liu W; Dai Q; Lu N; Wei L; Ha J; Rong J; Mu R; You Q; Li Z; Guo Q
    Biochem Cell Biol; 2011 Jun; 89(3):287-98. PubMed ID: 21491996
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells.
    Wu Q; Kirschmeier P; Hockenberry T; Yang TY; Brassard DL; Wang L; McClanahan T; Black S; Rizzi G; Musco ML; Mirza A; Liu S
    J Biol Chem; 2002 Sep; 277(39):36329-37. PubMed ID: 12138103
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of p21(Waf1/Cip1) by garcinol via downregulation of p38-MAPK signaling in p53-independent H1299 lung cancer.
    Yu SY; Liao CH; Chien MH; Tsai TY; Lin JK; Weng MS
    J Agric Food Chem; 2014 Mar; 62(9):2085-95. PubMed ID: 24533688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin.
    Wiegering A; Matthes N; Mühling B; Koospal M; Quenzer A; Peter S; Germer CT; Linnebacher M; Otto C
    Neoplasia; 2017 Apr; 19(4):301-309. PubMed ID: 28284059
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neural precursor cell expressed, developmentally downregulated 8‑activating enzyme inhibitor MLN4924 sensitizes colorectal cancer cells to oxaliplatin by inducing DNA damage, G2 cell cycle arrest and apoptosis.
    Zheng W; Luo Z; Zhang J; Min P; Li W; Xu D; Zhang Z; Xiong P; Liang H; Liu J
    Mol Med Rep; 2017 May; 15(5):2795-2801. PubMed ID: 28447739
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
    Chen H; Shan J; Chen D; Wang R; Qi W; Wang H; Ke Y; Liu W; Zeng X
    J Cell Physiol; 2019 Jul; 234(7):11871-11881. PubMed ID: 30478995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.